ChemicalBook CAS DataBase List Triethyl phosphate

Triethyl phosphate synthesis

14synthesis methods

Product Name:Triethyl phosphate
CAS Number:78-40-0
Molecular formula:C6H15O4P
Molecular Weight:182.15

Triethyl phosphate is manufactured from diethyl ether and phosphorus pentoxide via a metaphosphate intermediate.
Prepared by the reaction of tetraethyl hypophosphate with ethanol in the presence of aluminum ethoxide or by treating triethyl phosphate with diethyl hydrogen phosphate.

64-17-5 Synthesis

64-17-5
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78-40-0
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Yield:78-40-0 97.7%

Reaction Conditions:

with trichlorophosphate in acetone at 10 - 30; under 10 Torr; for 4 h;

Steps:

8

In a 2L to of the three-port flask 368.56g, 8mol ethanol, then adding acetone 92.9g, 1 . 6mol, after stirring and mixing cooling to 10 °C the following, stirring next adds by drops 245.33g, 1 . 6mol phosphorus oxychloride, control the mixture temperature is not higher than 10 °C.50 minutes after the dropping. Stirring 10 minutes, under the condition of vacuum heating to 30 degrees, the vacuum degree 10mmHg, reaction 3h, the end of the reaction, adding containing 12.5g ethanol the sodium is mellow solution, stirring for one hour, water after cooling, dissolve, produce sodium chloride, separating, collecting the organic phase, the organic phase washed to neutral, moisture is removed by reduced pressure distillation and low-boiling ethanol and acetone, the purity is not less than 96% triethyl phosphate product the ester is thick 292.4g, the fractionating column, pressure reducing fractionated 285.6g triethyl phosphate, yield 97.7%, purity ≥ 99.5%.

References:

CN105859770,2016,A Location in patent:Paragraph 0044; 0045

64-17-5 Synthesis

64-17-5
692 suppliers
$10.00/50g