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ChemicalBook CAS DataBase List Ethanone, 1-(1H-pyrrolo[2,3-c]pyridin-3-yl)- (9CI)

Ethanone, 1-(1H-pyrrolo[2,3-c]pyridin-3-yl)- (9CI) synthesis

1synthesis methods
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Yield:67058-71-3 74%

Reaction Conditions:

Stage #1: 6-azaindolewith aluminum (III) chloride in dichloromethane at 25; for 1 h;Inert atmosphere;
Stage #2: acetyl chloride in dichloromethane at 25; for 18 h;Inert atmosphere;

References:

Kettle, Jason G.;Ballard, Peter;Bardelle, Catherine;Cockerill, Mark;Colclough, Nicola;Critchlow, Susan E.;Debreczeni, Judit;Fairley, Gary;Fillery, Shaun;Graham, Mark A.;Goodwin, Louise;Guichard, Sylvie;Hudson, Kevin;Ward, Richard A.;Whittaker, David [Journal of Medicinal Chemistry,2015,vol. 58,# 6,p. 2834 - 2844]

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