ChemicalBook CAS DataBase List 2-chloro-1-(1-chlorocyclopropyl)ethanone

2-chloro-1-(1-chlorocyclopropyl)ethanone synthesis

5synthesis methods

Product Name:2-chloro-1-(1-chlorocyclopropyl)ethanone
CAS Number:120983-72-4
Molecular formula:C5H6Cl2O
Molecular Weight:153.01

2-chloro-1-(1-chlorocyclopropyl)ethan-1-one was prepared by 1-(1-chlorocyclopropyl)ethanone stirred in DCM and methanol with chlorine gas at 0℃ for 3h.

63141-09-3 Synthesis

63141-09-3
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2-chloro-1-(1-chlorocyclopropyl)ethanone

120983-72-4
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Yield:120983-72-4 98.5%

Reaction Conditions:

with chlorine at 10 - 25; under 760.051 Torr; for 2 h;Temperature;Reagent/catalyst;

Steps:

1 Example 1

The temperature of the temperature control apparatus was adjusted to 10 ° C, the system pressure was 1 atm, Under the condition of no solvent, the substrate flow rate was adjusted to 10 mol / h, Chlorine flow 10.5 ~ 11mol / h, with the metering pump material into the reaction system for reaction, According to the reaction requirements, control reaction time is 30s. As the reaction progresses, The temperature at the outlet of the reactor was gradually increased to 25C Line 2 exit temperature increased to 20 ° C.The reaction was terminated at 2h and the sample was analyzed by GC. The purity of product GC was 99.2% and the yield was 98.5%.

References:

CN105384617,2016,A Location in patent:Paragraph 0019

765-43-5 Synthesis