Welcome to chemicalbook!
Chinese English Japanese Germany Korea
010-86108875
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook CAS DataBase List Ethyl pyrazole-3-carboxylate
5932-27-4

Ethyl pyrazole-3-carboxylate synthesis

10synthesis methods
Ethanol

64-17-5

5-Pyrazolecarboxylic acid

1621-91-6

Ethyl pyrazole-3-carboxylate

5932-27-4

Pyrazole-3-carboxylic acid (1.112 g, 10 mmol) was dissolved in ethanol (50 mL) at 80 °C, followed by slow addition of concentrated sulfuric acid (2 mL). The reaction mixture was kept under stirring for 2 hours. Upon completion of the reaction, ethyl 1H-pyrazole-3-carboxylate (1.350 g, 9.6 mmol, 96% yield) was obtained.

-

Yield:5932-27-4 96%

Reaction Conditions:

with sulfuric acid at 80; for 2 h;

Steps:

Synthesis of Eopzc
To solution of ethanol (50 mL) and 3-pyrazolecarboxylicacid (1.112 g 10 mmol) at 80 °C was added concentratedsulfuric acid (2 mL), and after 2 h of stirring theethyl 1H-pyrazole-3-carboxylate was obtained (1.350 g,9.6 mmol, 96 %).

References:

Feng, Chao;Li, Xue-Jing;Zhang, Duo;Qu, Zhi-Rong;Zhao, Hong [Journal of the Iranian Chemical Society,2016,vol. 13,# 5,p. 823 - 830]

FullText

Ethyl pyrazole-3-carboxylate Related Search: