Gallic acid synthesis
- Product Name:Gallic acid
- CAS Number:149-91-7
- Molecular formula:C7H6O5
- Molecular Weight:170.12
13677-79-7
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$18.00/100mg
149-91-7
659 suppliers
$5.00/25g
Yield:-
Reaction Conditions:
with silver nitrate;potassium hydroxide in water at 60;
Steps:
4.2. Preparation of Aryl Carboxylic Acids 2a-p [30]
General procedure: In a 100 mL round-bottom flask, 20 mmol of silver nitrate was suspended in 60 mL ofpotassium hydroxide aqueous solution (7%), which was stirred for 5 min before 10 mmol ofthe appropriate aldehydes 1a-p was added into the suspension. The mixture was stirred at60 C for 1 h, then cooled to room temperature, and filtered. The filtrate was acidified witha hydrochloric acid solution (10%) until the formation of a precipitate, which was cooled inan ice bath, filtered out, and dried under vacuum. The crude products were characterizedby comparing their melting points with literature values as well as by 1H NMR analysis.Yields have ranged from 70 to 90%, and all solid products were directly used in the nextstep without further purification.
References:
Silva, Laís Peres;Santos, Ivanilson Pimenta;Silva, Dahara Keyse Carvalho;dos Reis, Bruna Padilha Zurita Claro;Meira, Cássio Santana;Castro, Marcos Venícius Batista de Souza;dos Santos Filho, José Maurício;Araujo-Neto, Jo?o Honorato de;Ellena, Javier Alcides;Silveira, Rafael Gomes da;Soares, Milena Botelho Pereira [Molecules,2022,vol. 27,# 23,art. no. 8343]
99-50-3
555 suppliers
$10.00/5g
149-91-7
659 suppliers
$5.00/25g
118-41-2
537 suppliers
$14.00/5g
149-91-7
659 suppliers
$5.00/25g