METHANESULFONIC ACID ANILINE synthesis
- Product Name:METHANESULFONIC ACID ANILINE
- CAS Number:103-06-0
- Molecular formula:C7H9NO3S
- Molecular Weight:187.22
Yield:-
Reaction Conditions:
with sodium hydrogensulfite in water at 50; for 3 h;
Steps:
1
In 100 parts of water, 31.2 parts of sodium hydrogen sulfite was dissolved. To this solution, 30.0 parts of a 30% formalin solution was added, and then, 27.9 parts of aniline was added dropwise. After the dropwise addition, the temperature of the solution was increased to 50°C and the solution was stirred for 3 hours at the same temperature and thereafter cooled to 5°C. The precipitated crystal was filtered and dried to obtain a compound represented by the formula (8). Subsequently, 52.5 parts of the compound of the formula (8) was dissolved in 300 parts of water while adjusting pH with sodium carbonate to 7.0 to 8.0. To the resultant solution, a suspension of the diazotized compound obtained in the aforementioned reaction was added dropwise at room temperature while maintaining pH at 7.0 to 8.0 with addition of sodium carbonate. The resultant mixture was stirred at room temperature for 5 hours while maintaining the same pH to obtain a solution containing the compound represented by the formula (9).
References:
NIPPON KAYAKU KABUSHIKI KAISHA EP1669413, 2006, A1 Location in patent:Page/Page column 12
