ChemicalBook CAS DataBase List Methyl 3,5-dihydroxyphenylacetate

Methyl 3,5-dihydroxyphenylacetate synthesis

15synthesis methods

Product Name:Methyl 3,5-dihydroxyphenylacetate
CAS Number:4724-10-1
Molecular formula:C9H10O4
Molecular Weight:182.17

67-56-1 Synthesis

67-56-1
727 suppliers
$7.29/5ml-f

4670-09-1
63 suppliers
$60.00/100mg

4724-10-1
65 suppliers
$40.00/1 g

Yield: 100%

Reaction Conditions:

thionyl chloride at 20;

Steps:

10.A
Intermediate 10; (3-Cyclopropyl-5-hydroxy-phenyl)-acetic acid methyl ester; [0094] Step A; (3,5-Dihydroxy-phenyl)-acetic acid (5 g, 29.7 mmol) is dissolved in MeOH (30 mL). Catalytic amounts of thionyl chloride (-0.25 ml_) are added and the solution is stirred at rt overnight. The solvent is removed in vacuo to give (3,5-dihydroxy- phenyl)-acetic acid methyl ester 6 (5.44 g, quant.): MS calcd. for C₉Hi iθ₄ (M+H*) 183.1, found 183.0.

References:

IRM LLC WO2007/56366, 2007, A2 Location in patent:Page/Page column 28

6512-32-9 Synthesis