ChemicalBook CAS DataBase List Methyl thioglycolate

Methyl thioglycolate synthesis

4synthesis methods

Product Name:Methyl thioglycolate
CAS Number:2365-48-2
Molecular formula:C3H6O2S
Molecular Weight:106.14

67-56-1 Synthesis

67-56-1
727 suppliers
$9.00/25ml

68-11-1 Synthesis

68-11-1
392 suppliers
$12.00/25g

2365-48-2
334 suppliers
$14.00/25g

Yield:2365-48-2 94%

Reaction Conditions:

with sulfuric acid for 4 h;Reflux;

Steps:

Synthesis of Methyl Thioglycolate (I)

A mixture of methanol (0.4mol) and mercapto acetic acid(1 mol) was refluxed while stirred and concentrated H2SO4 (0.8 g) was added to the solution. Then the mixture was refluxed for 4h. After, the mixture was extracted three times with Cyclohexane (80 mL) and toluene (40 mL), then the extractive solution was dried using CaCl2, the solvent was evaporated in a vacuum to yield the colorless liquid (34g, 94%).

References:

Tan, Chunbin;Liu, Xiaoling;Du, Hongfei [Revue Roumaine de Chimie,2019,vol. 64,# 3,p. 271 - 276]

1665-64-1 Synthesis