Mitomycin C synthesis
- Product Name:Mitomycin C
- CAS Number:50-07-7
- Molecular formula:C15H18N4O5
- Molecular Weight:334.33
![1,2,5-Metheno-1H,5H-imidazo[2,1-i]indole-7,10-dione, 6-[[(aminocarbonyl)oxy]methyl]-2,3,6,6a-tetrahydro-5,8-dimethoxy-9-methyl-, (1S,2S,4S,5R,6S,6aR,10aS,11S)- (9CI)](/CAS/20200611/GIF/110934-24-2.gif)
110934-24-2
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50-07-7
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Yield:-
Steps:
Multi-step reaction with 2 steps
1: 1) H2, 2) air / 1) 10percent Pd on carbon / 1) acetonitrile, 1 atm, 25 deg C, 2 h, 2) 25 deg C, 2 h
2: 75 percent / 6 M methanol. NH3 / 5 h / 25 °C
References:
Kasai;Kono;Ikeda;Yoda;Hirayama [Journal of Organic Chemistry,1992,vol. 57,# 26,p. 7296 - 7299]
![2,7b-Diazabenzo[f]cycloprop[cd]indene-4,7-dione, 3-[[(aminocarbonyl)oxy]methyl]-1,2,2a,3,7c,7d-hexahydro-2a,5-dimethoxy-6-methyl-, (2aR,3S,7cS,7dS)- (9CI)](/CAS/20211123/GIF/91917-64-5.gif)
91917-64-5
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![Azirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione, 8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methyl-6-[(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)oxy]-, [1aS-(1aα,8β,8aα,8bα)]- (9CI)](/CAS/20210305/GIF/128583-70-0.gif)
128583-70-0
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50-07-7
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92056-69-4
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![Carbamic acid, [(dimethylamino)methylene]-, [6-[[(dimethylamino)methylene]amino]-1,1a,2,4,7,8,8a,8b-octahydro-8a-methoxy-5-methyl-4,7-dioxoazirino[2',3':3,4]pyrrolo[1,2-a]indol-8-yl]methyl ester, [1aS-(1aα,8β,8aα,8bα)]- (9CI)](/CAS/20210305/GIF/88948-91-8.gif)
88948-91-8
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91-00-9
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50-07-7
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88949-01-3
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![Azirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione, 8-[[(aminocarbonyl)oxy]methyl]-6-[(diphenylmethyl)amino]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methyl-, [1aS-(1aα,8β,8aα,8bα)]- (9CI)](/CAS/20210305/GIF/110971-78-3.gif)
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