N-(4-chlorophenyl)thiazol-2-amine synthesis
4synthesis methods
- Product Name:N-(4-chlorophenyl)thiazol-2-amine
- CAS Number:100585-58-8
- Molecular formula:C9H7ClN2S
- Molecular Weight:210.68
Yield:100585-58-8 92%
Reaction Conditions:
with tris-(dibenzylideneacetone)dipalladium(0);t-BuBrettPhos;potassium carbonate in tert-butyl alcohol at 90; for 16 h;Inert atmosphere;Molecular sieve;
References:
McGowan, Meredeth A.;Henderson, Jaclyn L.;Buchwald, Stephen L. [Organic Letters,2012,vol. 14,# 6,p. 1432 - 1435] Location in patent:supporting information; experimental part
