ChemicalBook CAS DataBase List N,N-Dimethylbenzamide

N,N-Dimethylbenzamide synthesis

10synthesis methods

Product Name:N,N-Dimethylbenzamide
CAS Number:611-74-5
Molecular formula:C9H11NO
Molecular Weight:149.19

124-40-3
501 suppliers
$18.00/100ml

65-85-0 Synthesis

65-85-0
1313 suppliers
$10.00/25 g

611-74-5
205 suppliers
$10.00/5g

Yield:611-74-5 75%

Reaction Conditions:

with tetrabutylammomium bromide;iodine;potassium hydroxide in water at 20; for 2.5 h;Irradiation;

Steps:

General procedure for the catalytic reactions
General procedure: A 10 mL quartz tube equipped was charged with aniline (0.70 mmol), benzoic acid (0.50 mmol), TBAB (0.5 mmol), KOH (1.0 mmol), I₂ (0.10 mmol), and water (2.5 mL). The reaction mixture was stirred under irradiation of sunlight at room temperature for 2.5 h. After the reaction was completed, the organic layer was collected by ethyl acetate extraction. The solution of the crude product was concentrated in vacuo, and the residue was purified by column chromatography on a silica gel (petroleum ether/ethyl acetate=5/1) to afford the target product as a white solid.

References:

Wang, Jin;Hou, Huiqing;Hu, Yongzhi;Lin, Jin;Wu, Min;Zheng, Zhiqiang;Xu, Xiuzhi [Tetrahedron Letters,2021,vol. 65,art. no. 152801] Location in patent:supporting information

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124-40-3
501 suppliers
$18.00/100ml

100-51-6 Synthesis