Welcome to chemicalbook!
Chinese English Japanese Germany Korea
010-86108875
logo
Inquriy
Try our best to find the right business for you.
Messages
Do not miss inquiry messages Please log in to view all inquiry messages.
My chemicalbook

Welcome back!

Structured search
18162-48-6872-50-4Methylene ChloridenaphthaleneTHFTitanium Dioxide
ChemicalBook CAS DataBase List Teflubenzuron
83121-18-0

Teflubenzuron synthesis

5synthesis methods
Teflubenzuron is synthesised through a multi-step organic process designed to construct its complex difluorinated and dichlorinated aromatic structure. The production typically begins with the preparation of two key intermediates: a substituted benzoyl chloride and a substituted phenylurea. One route involves reacting 2,6-difluorobenzoyl chloride with 3,5-dichloro-2,4-difluoroaniline to form the urea linkage central to teflubenzuron’s structure. This condensation reaction is carried out under controlled conditions, often using solvents like toluene and a base such as triethylamine to facilitate the coupling. The final compound is then purified.
60731-73-9 Synthesis
2,6-Difluorobenzoyl isocyanate

60731-73-9
54 suppliers
inquiry

83121-15-7 Synthesis
2,4-Difluoro-3,5-dichloroaniline

83121-15-7
172 suppliers
$10.00/1g

Teflubenzuron

83121-18-0
162 suppliers
$56.79/250mg-r

-

Yield:83121-18-0 96%

Reaction Conditions:

in chloroform;toluene for 2 h;Reflux;

Steps:

1-3
Put 465g of 2,4-difluoro-3,5-dichloroaniline, 300g of toluene, and 300g of chloroform into a 2000mL reaction flask, add 426g of 2,6-difluorobenzoyl isocyanate dropwise at room temperature, and then heat up to reflux for reaction. After 2 hours, after passing the test, the temperature was lowered, filtered with suction, and dried to obtain 842.8 g of Triflubenzuron with a content of 99.1% and a yield of 96%.

References:

Zhejiang Nanjiao Chemical Co., Ltd.;Yi Miao;Yin Kai;Yang Jiangyu;Wu Hao;Wu Wenliang;Yu Jiang;Gu Minmin;Chai Huaqiang CN111995538, 2020, A Location in patent:Paragraph 0056; 0062; 0064; 0070; 0072; 0078

FullText

1897-52-5 Synthesis
2,6-Difluorobenzonitrile

1897-52-5
557 suppliers
$7.00/10g

Teflubenzuron

83121-18-0
162 suppliers
$56.79/250mg-r

References
118-69-4 Synthesis
2,6-Dichlorotoluene

118-69-4
296 suppliers
$14.00/5g

Teflubenzuron

83121-18-0
162 suppliers
$56.79/250mg-r

References
2,6-Dichlorobenzal chloride

81-19-6
115 suppliers
$33.00/25G

Teflubenzuron

83121-18-0
162 suppliers
$56.79/250mg-r

References
2,6-Dichlorobenzonitrile

1194-65-6
503 suppliers
$10.60/1gm:

Teflubenzuron

83121-18-0
162 suppliers
$56.79/250mg-r

References

Teflubenzuron Related Search:

Transfluthrin Dichlorodiphenylsilane Florfenicol 3-Fluoroanisole 4-Fluorobenzaldehyde Dichloromethylphenylsilane Glycine 2'-Fluoroacetanilide 4-FLUOROPHENYLUREA 1-CHLORO-2,4-DIFLUOROBENZENE