ChemicalBook CAS DataBase List Valeronitrile

Valeronitrile synthesis

13synthesis methods

Product Name:Valeronitrile
CAS Number:110-59-8
Molecular formula:C5H9N
Molecular Weight:83.13

Valeronitrile can be synthesized by dehydration of valeronamide. The nitrile is also found in nature and is a constituent of coal gasification and oil shale processing waste water, sewage wastewater and tobacco smoke.

13284-42-9 Synthesis

13284-42-9
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$88.00/5mL

110-59-8
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$9.00/1g

Yield:110-59-8 98.4%

Reaction Conditions:

with hydrogen in ethanol at 60;Inert atmosphere;Large scale;

Steps:

1 Example 1 (small test)

(1) Hydrogenation reduction reactionAdd 500g pentenonitrile, 1000g ethanol, 2.5g each of the new catalyst and amorphous Fe-Mo-Ni-Al catalyst into the hydrogenation reactor,Turn on the stirring, replace with nitrogen 3 times, and replace with hydrogen 3 times. The hydrogen pressure is controlled at 0.2Mpa, and the temperature is raised to 60°C.The reaction was finished after 2h reaction.(2) Post-treatment processAfter the reaction liquid was filtered, the filtrate was rectified. The front distillate is 999g of ethanol (95%), which is recovered and used;The middle distillate is 502g of valeronitrile (99.8%), which is reconstituted into a small amount of impurities.Based on the addition amount of pentenenitrile, the yield of the product was 98.4%, and the purity was 99.8%.

References:

CN113135839,2021,A Location in patent:Paragraph 0032-0036