Terpineol Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R38:Reizt die Haut.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S37:Geeignete Schutzhandschuhe tragen.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Beschreibung
Terpineol is a monoterpene alcohol that has been found in a variety of plants, including
Cannabis, and has diverse biological activities. Terpineol contains the four isomers α-, β-, and γ-terpineol and terpinen-4-ol. α-Terpineol has antibacterial and antinociceptive properties. It is active against a variety of periodontopathic and cariogenic bacteria, including strains of
P. gingivalis,
F. nucleatum, and
A. actinomycetemcomitans (MICs = 0.1-0.8 mg/ml), however, it is toxic to KB cells when used at a concentration of 0.8 mg/ml. It also reduces mechanical hyperalgesia, as well as spontaneous and palpation-induced nociception, in a mouse model of cancer-induced pain beginning on day 5 when administered at a dose of 50 mg/kg per day. Terpinen-4-ol has anticonvulsant properties, inhibiting pentylenetetrazol-induced seizures in mice when used at doses ranging from 50 to 200 mg/kg. α-Terpineol and terpinen-4-ol also have anti-inflammatory properties, reducing LPS-induced production of IL-1β, IL-6, and IL-10, but not TNF-α, in U937 cells. This product is a mixture of α-, β-, and γ-terpineol.
Chemische Eigenschaften
It appears as colorless liquid or low-melting transparent crystal with a clove flavor. 1 part of terpineol can be dissolved in 2 parts (volume) of 70% ethanol solution, being slightly soluble in water and glycerol.
Occurrence
Reported to be found in more than 200 derivatives from leaves, herbs and flowers [Fenaroli 's Handbook of Flavor Ingredients, 1971 ; Gildemeister & Hoffman, 1962).
Verwenden
Terpineol is a monoterpene alcohol with potential antifungal, antioxidant and antiproliferative activities. This product is a mixture of isomers.
synthetische
From terpin hydrate by the splitting off of the elements of water by chemical means (Bedoukian, 1967).
Allgemeine Beschreibung
α-Terpineol is a cyclic monoterpene. It is one of the major monoterpenol component of the cultivar Gewürztraminer and other aroma-rich grape varieties. α-Terpineol, a monoterpenoid alcohol, has been investigated for its anticonvulsant activity. It was one of the insecticidal constituent of the essential oils of
Dahlia pinnata.FCC includes the following isomers in the listed purity: alpha-, (E)-beta, (Z)-beta, gamma-, terpinen-4-ol, and terpinen-1-ol.
Terpineol Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
