Cholesteryl hemisuccinate
- CAS No.
- 1510-21-0
- Chemical Name:
- Cholesteryl hemisuccinate
- Synonyms
- CHOLESTERYL HYDROGEN SUCCINATE;cholesterylsuccinate;Cholesterol Succinate;CHOLESTERYL HEMISUCCINATE;MONO-CHOLESTERYL-SUCCINATE;CHOLESTEROL HYDROGEN SUCCINATE;5-CHOLESTEN-3β-OL HEMISUCCINATE;Cholesterol Hydrogen Succinate >5-CHOLESTEN-3-BETA-OL HEMISUCCINATE;SUCCINIC ACID MONOCHOLESTEROL ESTER
- CBNumber:
- CB0336321
- Molecular Formula:
- C31H50O4
- Molecular Weight:
- 486.73
- MDL Number:
- MFCD00037705
- MOL File:
- 1510-21-0.mol
| Melting point | 178 °C |
|---|---|
| Boiling point | 586.0±43.0 °C(Predicted) |
| Density | 1.06±0.1 g/cm3(Predicted) |
| refractive index | -34 ° (C=2, CHCl3) |
| storage temp. | -20°C |
| solubility | Chloroform (Slightly), Methanol (Slightly, Heated, Sonicated) |
| form | Solid |
| pka | 4.40±0.17(Predicted) |
| color | White to Off-White |
| InChIKey | WLNARFZDISHUGS-BLYFUZNHSA-N |
| LogP | 10.708 (est) |
| CAS DataBase Reference | 1510-21-0(CAS DataBase Reference) |
| FDA UNII | T3J4KS4201 |
Cholesteryl hemisuccinate price More Price(21)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | C6512 | Cholesteryl hemisuccinate | 1510-21-0 | 5g | $271 | 2024-03-01 | Buy |
| Sigma-Aldrich | C6512 | Cholesteryl hemisuccinate | 1510-21-0 | 25g | $897 | 2024-03-01 | Buy |
| Cayman Chemical | 25698 | Cholesteryl Hemisuccinate ≥95% | 1510-21-0 | 1g | $44 | 2024-03-01 | Buy |
| Cayman Chemical | 25698 | Cholesteryl Hemisuccinate ≥95% | 1510-21-0 | 5g | $183 | 2024-03-01 | Buy |
| Cayman Chemical | 25698 | Cholesteryl Hemisuccinate ≥95% | 1510-21-0 | 10g | $341 | 2024-03-01 | Buy |
Cholesteryl hemisuccinate Chemical Properties,Uses,Production
Description
Cholesteryl hemisuccinate is a cholesterol ester with anticancer activity. It inhibits the growth of murine C1498 myeloid and L1210 lymphocytic leukemia cells when used at concentrations of 50 and 150 μM, respectively. Cholesteryl hemisuccinate acts as an ionizable anionic detergent and is commonly used to stabilize unilamellar vesicles and liposomes. It has also been used as an emulsifying agent in various vesicular drug delivery systems for anticancer drugs, antibiotics, and oligonucleotides and to solubilize various proteins including chemokine receptor 1 as well as erythrocyte ghosts.
Uses
Cholesteryl Hemisuccinate is an oxidation product of polyunsaturated fatty acid of cholesterol that alters lysosome structure and functions and induces proinflammatory cytokine production in macrophages.
Definition
ChEBI: Cholesteryl hemisuccinate is a dicarboxylic acid monoester resulting from the formal condensation of the hydroxy group of cholesterol with one of the carboxy groups of succinic acid. A detergent that is often used to replace cholesterol in protein crystallography, biochemical studies of proteins, and pharmacology. It has a role as a detergent. It is a cholestane ester, a dicarboxylic acid monoester and a hemisuccinate. It is functionally related to a cholesterol.
General Description
Cholesteryl hemisuccinate (CHEMS) is an acidic cholesterol ester.
Biochem/physiol Actions
CHEMS can help to maintain the stability of dioleoylphosphatidylethanolamine (DOPE). This amphipathic lipid is used in mixtures with dioleoylphosphatidylethanolamine (DOPE) to form ′pH sensitive′ fusogenic vesicles. It can control cell growth.
Cholesteryl hemisuccinate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15932 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | CHINA | 52867 | 58 |
| Henan Alfa Chemical Co., Ltd | +8618339805032 | alfa4@alfachem.cn | China | 12755 | 58 |
| Alfa Chemistry | +1-5166625404 | Info@alfa-chemistry.com | United States | 21317 | 58 |
| Nanjing Doge Biomedical Technology Co., Ltd | +86-25-58227606 +86-15305155328 | sales@dogechemical.com | China | 4128 | 58 |
View Lastest Price from Cholesteryl hemisuccinate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-02 | CHEMS
1510-21-0
|
US $0.00 / g | 100g | >95.00% | 100g | Xian confluore Biological Technology Co., Ltd. | |
 |
2022-10-10 | Cholesteryl hemisuccinate
1510-21-0
|
US $0.00-0.00 / KG | 1KG | 98% | 1ton | Henan Aochuang Chemical Co.,Ltd. | |
 |
2021-08-12 | Cholesteryl hemisuccinate
1510-21-0
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |
-
- CHEMS
1510-21-0
- US $0.00 / g
- >95.00%
- Xian confluore Biological Technology Co., Ltd.
-
- Cholesteryl hemisuccinate
1510-21-0
- US $0.00-0.00 / KG
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- Cholesteryl hemisuccinate
1510-21-0
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
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