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Isopropyl palmitate

CAS No.
142-91-6
Chemical Name:
Isopropyl palmitate
Synonyms
ISOPROPYL HEXADECANOATE;Deltyl;plymouthipp;ISOPROPYLPALMITAT;kesscoisopropylpalmitate;Isopal;Isopalm;Emcol-IP;estol103;ja-faipp
CBNumber:
CB0451826
Molecular Formula:
C19H38O2
Molecular Weight:
298.5
MDL Number:
MFCD00008993
MOL File:
142-91-6.mol
MSDS File:
SDS
Last updated:2024-03-01 22:00:49

Isopropyl palmitate Properties

Melting point 11-13 °C (lit.)
Boiling point 160°C 2mm
Density 0.852 g/mL at 25 °C (lit.)
vapor pressure 0.007Pa at 25℃
refractive index n20/D 1.438(lit.)
Flash point >230 °F
storage temp. 2-8°C
solubility <0.001g/l
color Colourless
Odor very sl. odor
Water Solubility Not miscible or difficult to mix with water.
BRN 1786567
InChIKey XUGNVMKQXJXZCD-UHFFFAOYSA-N
LogP 8.16
CAS DataBase Reference 142-91-6(CAS DataBase Reference)
Substances Added to Food (formerly EAFUS) ISOPROPYL PALMITATE
FDA 21 CFR 310.545
EWG's Food Scores 1
FDA UNII 8CRQ2TH63M
NIST Chemistry Reference Isopropyl palmitate(142-91-6)
EPA Substance Registry System Isopropyl palmitate (142-91-6)
Cosmetics Info Isopropyl Palmitate

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280a-P305+P351+P338-P321-P332+P313-P337+P313
Hazard Codes  Xi
Risk Statements  36/38-36/37/38
Safety Statements  26-36
WGK Germany  -
RTECS  RT4900000
TSCA  Yes
HS Code  29157090
Toxicity mouse,LD50,intraperitoneal,100mg/kg (100mg/kg),National Technical Information Service. Vol. AD277-689,
NFPA 704
1
1 0

Isopropyl palmitate price More Price(29)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 291781 Isopropyl palmitate technical grade, 90% 142-91-6 1l $78.7 2024-03-01 Buy
Sigma-Aldrich 1350603 Isopropyl palmitate United States Pharmacopeia (USP) Reference Standard 142-91-6 500mg $474 2024-03-01 Buy
TCI Chemical P0005 Isopropyl Palmitate >97.0%(GC) 142-91-6 25mL $17 2024-03-01 Buy
TCI Chemical P0005 Isopropyl Palmitate >97.0%(GC) 142-91-6 500mL $32 2024-03-01 Buy
Alfa Aesar L04276 Isopropyl palmitate, tech. 85% 142-91-6 250ml $22.65 2024-03-01 Buy
Product number Packaging Price Buy
291781 1l $78.7 Buy
1350603 500mg $474 Buy
P0005 25mL $17 Buy
P0005 500mL $32 Buy
L04276 250ml $22.65 Buy

Isopropyl palmitate Chemical Properties,Uses,Production

Chemical Properties

Clear colorless liquid

Chemical Properties

Isopropyl palmitate is a clear, colorless to pale yellow-colored, practically odorless viscous liquid that solidifies at less than 16°C.

Uses

Pharmaceutic aid (vehicle, oleaginous).

Uses

Isopropyl palmitate is used to formulate and evaluate the suitability of pluronic lecithin organogels containing flurbiprofen for topical application and to characterize microemulsion systems of isopropyl palmitate, water and 2:1 Brij 97, and 1-butanol by different experimental techniques.

Uses

isopropyl palmitate is an emollient and moisturizer, it also acts as a binder and solvent. Similar to isopropyl myristate, it is produced from the combination of palmitic acid (coconut or palm oil) and isopropyl alcohol. enzymes are able to metabolize this ingredient and studies do not show allergic reactions or toxicity. Some sources indicate comedogenicity potential.

Definition

ChEBI: Isopropyl palmitate is a fatty acid ester obtained by the formal condensation of carboxy group of palmitic acid with propan-2-ol. Metabolite observed in cancer metabolism. It has a role as a human metabolite. It is a fatty acid ester and an isopropyl ester. It is functionally related to a hexadecanoic acid.

Production Methods

Isopropyl palmitate is prepared by the reaction of palmitic acid with propan-2-ol in the presence of an acid catalyst. A high-purity material is also commercially available, which is produced by enzymatic esterification at low temperatures.

General Description

Isopropyl palmitate is an analog of isopropyl myristate and an aliphatic ester used as a flavoring ingredient in food industry. It is one of the volatile compounds found in Psidium salutare fruits and boiled buckwheat flour.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Pharmaceutical Applications

Isopropyl palmitate is a nongreasy emollient with good spreading characteristics, used in topical pharmaceutical formulations and cosmetics such as: bath oils; creams; lotions; make-up; hair care products; deodorants; lip products; suntan preparations; and pressed powders.
Isopropyl palmitate is an established penetration enhancer for transdermal systems. It has also been used in controlled-release percutaneous films. Table I: Uses of isopropyl palmitate

Side effects

Side effects for the skin: If overused, isopropyl palmitate may cause acne, blackheads, whiteheads, and clogged pores. Depending on the content of the ingredients in the product, the skin may experience some irritation. If isopropyl palmitate is used without dilution, it may cause comedoles. People with oily skin should also avoid isopropyl palmitate.
Side effects for hair: Excessive use of products containing isopropyl palmitate on hair can make hair look untidy, oily, and untidy due to excessive moisture in the hair. When there is an open wound on the scalp, isopropyl palmitate should also be avoided.

Safety

Isopropyl palmitate is widely used in cosmetics and topical pharmaceutical formulations, and is generally regarded as a relatively nontoxic and nonirritant material.
LD50 (mouse, IP): 0.1 g/kg

storage

Isopropyl palmitate is resistant to oxidation and hydrolysis, and does not become rancid. It should be stored in a well-closed container, above 16°C, and protected from light.

Regulatory Status

Included in the FDA Inactive Ingredients Database (topical and transdermal preparations). Used in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.

57-10-3
67-63-0
142-91-6
Synthesis of Isopropyl palmitate from Palmitic acid and Isopropyl alcohol

Isopropyl palmitate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 422)Suppliers
Supplier Tel Email Country ProdList Advantage
Shandong Zhishang New Material Co., Ltd.
+8617653113209 sales002@sdzschem.com China 3050 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418671 sales@tnjchem.com China 34572 58
GIHI CHEMICALS CO.,LIMITED
+8618058761490 info@gihichemicals.com China 50002 58
Yancheng Green Chemicals Co.,Ltd
+undefined-86-25-86655873 info@royal-chem.com China 114 58
Gansu Jinyuantai New Material Co., Ltd.
+86-025-86618065 +86-13914714331 sales@jinyuantaichem.com China 73 58
Ningxia Jinhua Chemical Co.,Ltd
025-52279164 info@nxjhchem.com China 79 58
Henan Bao Enluo International TradeCo.,LTD
+86-17331933971 +86-17331933971 deasea125996@gmail.com China 2504 58
Henan Fengda Chemical Co., Ltd
+8613613820652 info@fdachem.com China 4685 58
Shandong Juchuang Chemical Co., LTD
+86-18885615001 +86-18885615001 admin@juchuangchem.com China 387 58
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29797 60

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  • Dec 25,2023

View Lastest Price from Isopropyl palmitate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Isopropyl palmitate pictures 2024-03-19 Isopropyl palmitate
142-91-6
US $5.00 / KG 100KG 99% 1000kg Hebei Yime New Material Technology Co., Ltd.
Isopropyl Palmitate pictures 2024-03-18 Isopropyl Palmitate
142-91-6
US $400.00 / KG 175KG 98% 10 tons Ningxia Jinhua Chemical Co.,Ltd
Isopropyl Palmitate pictures 2024-03-18 Isopropyl Palmitate
142-91-6
US $399.00 / kg 175kg 98.2% 10 tons Yancheng Green Chemicals Co.,Ltd
kesscoipp Lexol IPP Liponate IPP nikkolipp Palmitic acid esters Plymouth ipp Radia 7200 Sinnoester PIT sinnoesterpit Starfol ipp starfolipp ISOPROPYL PALMITATE 90+% ISOPROPYL PALMITATE, TECH., 90% PALMITIC ACID ISOPROPYL ESTER 95+% PALMITIC ACID ISOPROPYL ESTER 90% isopropylpalmitate,2-methylpropylhexadecanoate ISOPROPYLPALMITATE,NF HEXADECANOIC ACID 1-METHYLETHYL ESTER Palmitinsureisopropylester ISOPROPYL PALMITATE pure Propan-2-yl hexadecanoate Isopropyl PalMitate, NF, EP Isopropyl Palmitate (500 mg) Radia 7732 (IPP) Isopropyl palmitate technical grade, 90% 1-Methylethyl ester1-methylethyl hexandecanoate 1-methylethyl hexadecanoate 1-Methylethylhexadecanoate 2-propyl hexadecanoate Crodamol IPP crodamolipp Deltyl Prime deltylprime Emcol-IP Emerest 2316 emerest2316 Estol 103 estol103 Hexadecanoic acid, isopropyl ester Hexadecanoic acidisopropyl n-hexadecanoate hexadecanoicacid,isopropylester hexadecanoicacidisopropylester Isopal Isopalm Isopropyl ester of hexadecanoic acid Isopropyl n-hexadecanoate isopropyln-hexadecanoate Isopropylpalmilate Ja-fa ipp Ja-fa ippkessco ja-faipp Kessco IPP Kessco isopropyl palmitate PALMITIC ACID ISOPROPYL ESTER ISOPROPYL PALMITATE Stepan D-70 stepand-70 Tegester isopalm