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Isopropyl acetoacetate

CAS No.
542-08-5
Chemical Name:
Isopropyl acetoacetate
Synonyms
IPAA;Isopropylacetoactetate;ACIP;Isopropylacetoacetat;Isopropyl acetoaceta;ISOPROPYL ACETOACETATE;Isopropyl3-oxobutyrate;Isopropyl3-oxobutanoate;IsopropylAcetoacetate>Isopropylacetoacetate,98%
CBNumber:
CB1293982
Molecular Formula:
C7H12O3
Molecular Weight:
144.17
MDL Number:
MFCD00043933
MOL File:
542-08-5.mol
Last updated:2023-09-08 13:28:03

Isopropyl acetoacetate Properties

Melting point -27°C
Boiling point 95 °C52 hPa(lit.)
Density 0.989 g/mL at 20 °C(lit.)
refractive index n20/D 1.418
Flash point 73°C
solubility Chloroform, Ethyl Acetate, Methanol, Toluene,
form Colourless Liquid
pka 11.67±0.46(Predicted)
color Colorless to Almost colorless
Water Solubility Slightly miscible with water.
Merck 14,5206
BRN 1757046
InChIKey GVIIRWAJDFKJMJ-UHFFFAOYSA-N
LogP 1.060 (est)
CAS DataBase Reference 542-08-5(CAS DataBase Reference)
FDA UNII 38GTB2C6XC
EPA Substance Registry System Butanoic acid, 3-oxo-, 1-methylethyl ester (542-08-5)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H227-H319-H335
Precautionary statements  P210e-P261-P280a-P305+P351+P338-P405-P501a
Hazard Codes  Xi
Risk Statements  38
Safety Statements  26-36-24/25
WGK Germany  1
TSCA  Yes
HS Code  29183000
NFPA 704
2
2 0

Isopropyl acetoacetate price More Price(16)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 689092 Isopropyl acetoacetate Lonza quality, ≥99.0% (GC) 542-08-5 1kg $151 2024-03-01 Buy
Sigma-Aldrich 689092 Isopropyl acetoacetate Lonza quality, ≥99.0% (GC) 542-08-5 25kg $2510 2024-03-01 Buy
TCI Chemical I0826 Isopropyl Acetoacetate >97.0%(GC) 542-08-5 25g $38 2024-03-01 Buy
TCI Chemical I0826 Isopropyl Acetoacetate >97.0%(GC) 542-08-5 500g $469 2024-03-01 Buy
Alfa Aesar A11907 Isopropyl acetoacetate 98% 542-08-5 50g $37 2023-06-20 Buy
Product number Packaging Price Buy
689092 1kg $151 Buy
689092 25kg $2510 Buy
I0826 25g $38 Buy
I0826 500g $469 Buy
A11907 50g $37 Buy

Isopropyl acetoacetate Chemical Properties,Uses,Production

Chemical Properties

Colourless Liquid

Uses

Isopropyl acetoacetate is used as an intermediate for the manufacturing of agrochemicals and pharmaceutical products such as isradipine.

Uses

Isopropyl acetoacetate (IPAA) is used as intermediate for chemical synthesis. Product Data Sheet

Application

Isopropyl acetoacetate can be used as a reactant to synthesize:
Isopropyl 2-acetyl-3-phenyl-2-propenoate via Knoevenagel reaction in the presence of Ti(O-i-Pr)4.
Substituted 1,4-dihydropyridines by reacting with cinnamaldehydes and primary amines.
5-Isopropoxycarbonyl-6-methyl-4-phenyl-3,4-dihydropyrimidin-2(1H)-thione via Biginelli reaction with benzaldehyde and thiourea.

Synthesis Reference(s)

The Journal of Organic Chemistry, 26, p. 225, 1961 DOI: 10.1021/jo01060a055

674-82-8
67-63-0
542-08-5
Synthesis of Isopropyl acetoacetate from Acetyl ketene and Isopropyl alcohol

Isopropyl acetoacetate Preparation Products And Raw materials

Global( 290)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Mojin Biotechnology Co., Ltd
+86-13288715578 +86-13231137666 sales@hbmojin.com China 12409 58
Anhui Ruihan Technology Co., Ltd
+8617756083858 daisy@anhuiruihan.com China 994 58
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21703 55
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418679 +86-18949832763 info@tnjchem.com China 2989 55
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29919 58
Wuhan Boyuan Import & Export Co., LTD
+86-15175982296 15175982296; Mike@whby-chem.com China 983 58
Hebei Guanlang Biotechnology Co., Ltd.
+86-19930503282 alice@crovellbio.com China 8823 58
Xiamen AmoyChem Co., Ltd
+86-592-6051114 +8618959220845 sales@amoychem.com China 6387 58
Hubei xin bonus chemical co. LTD
86-13657291602 linda@hubeijusheng.com CHINA 22968 58

View Lastest Price from Isopropyl acetoacetate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
isopropyl acetoacetate pictures 2024-01-08 isopropyl acetoacetate
542-08-5
US $10.00-6.00 / L 1L 99.50% 30tons Wuhan Boyuan Import & Export Co., LTD
Isopropyl acetoacetate pictures 2023-09-08 Isopropyl acetoacetate
542-08-5
US $30.00 / kg 1kg 99% 1000t/year Anhui Ruihan Technology Co., Ltd
Isopropyl acetoacetate pictures 2023-08-29 Isopropyl acetoacetate
542-08-5
US $0.00 / KG 1KG 99% 50000KG/month Hebei Mojin Biotechnology Co., Ltd
3-oxo-butanoicaci1-methylethylester 3-Oxobutansαure-1-methylethylester 3-Oxo-butyricacidisopropylester Acetoaceticacid,isopropylester acetoaceticacidisopropylester Butanoicacid,3-oxo-,1-methylethylester Isopropyl3-oxobutanoate Isopropyl3-oxobutyrate ISOPROPYL ACETOACETATE ACIP Isopropyl acetoacetate(IPAA) ISOPROPYL ACETOACETATE, WACKER QUALITY Isopropylacetoacetate,98% Isopropylacetoacetat 3-oxo-butanoic acid 1-methylethyl ester 1-methyl-3-oxo-butanoic acid ethyl ester 3-Oxobutanoic acid isopropyl ester 3-ketobutyric acid isopropyl ester Isopropyl acetoaceta Acetoacetic Acid Isopropyl Ester Isopropyl 3-Oxobutyrate 3-Oxobutyric Acid Isopropyl Ester 3-oxobutanoic acid propan-2-yl ester IsopropylAcetoacetate> TIANFU-CHEM - Isopropyl acetoacetate IPAA Isopropylacetoactetate 542-08-5 524-08-5 CH3COCH2COOCHCH32 Esters Building Blocks C6 to C7 Carbonyl Compounds Organic Building Blocks Miscellaneous Reagents C6 to C7 Carbonyl Compounds Esters bc0001