L-Malic acid
- CAS No.
- 97-67-6
- Chemical Name:
- L-Malic acid
- Synonyms
- L-MALIC ACID;L-Malic;(2S)-2-hydroxybutanedioic acid;L-Mailcacid;HYDROXYBUTANEDIOIC ACID;L-Gydroxybutanedioicacid;apple acid;pinguosuan;(S)-(-)-MALIC ACID;-(-)-MaL
- CBNumber:
- CB0493594
- Molecular Formula:
- C4H6O5
- Molecular Weight:
- 134.09
- MDL Number:
- MFCD00064213
- MOL File:
- 97-67-6.mol
- MSDS File:
- SDS
Melting point | 101-103 °C (lit.) |
---|---|
Boiling point | 167.16°C (rough estimate) |
alpha | -2 º (c=8.5, H2O) |
Density | 1.60 |
vapor pressure | 0Pa at 25℃ |
FEMA | 2655 | L-MALIC ACID |
refractive index | -6.5 ° (C=10, Acetone) |
Flash point | 220 °C |
storage temp. | Store below +30°C. |
solubility | H2O: 0.5 M at 20 °C, clear, colorless |
form | Powder |
Specific Gravity | 1.595 (20/4℃) |
color | White |
PH | 2.2 (10g/l, H2O, 20℃) |
pka | (1) 3.46, (2) 5.10(at 25℃) |
Odor | odorless |
Odor Type | odorless |
optical activity | [α]20/D 30±2°, c = 5.5% in pyridine |
Water Solubility | soluble |
JECFA Number | 619 |
Merck | 14,5707 |
BRN | 1723541 |
InChIKey | BJEPYKJPYRNKOW-REOHCLBHSA-N |
LogP | -1.68 |
Substances Added to Food (formerly EAFUS) | L-MALIC ACID |
SCOGS (Select Committee on GRAS Substances) | L-Malic acid |
CAS DataBase Reference | 97-67-6(CAS DataBase Reference) |
FDA UNII | J3TZF807X5 |
NIST Chemistry Reference | Butanedioic acid, hydroxy-, (s)-(97-67-6) |
EPA Substance Registry System | Butanedioic acid, 2-hydroxy-, (2S)- (97-67-6) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H319 | |||||||||
Precautionary statements | P264-P280-P305+P351+P338-P337+P313 | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 36/37/38 | |||||||||
Safety Statements | 26-36-37/39 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | ON7175000 | |||||||||
TSCA | Yes | |||||||||
HS Code | 29181980 | |||||||||
NFPA 704 |
|
L-Malic acid price More Price(63)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 8.00384 | L-(-)-Malic acid for resolution of racemates for synthesis | 97-67-6 | 5G | $27.2 | 2024-03-01 | Buy |
Sigma-Aldrich | 8.00384 | L-(-)-Malic acid for resolution of racemates for synthesis | 97-67-6 | 10g | $39.7 | 2024-03-01 | Buy |
Sigma-Aldrich | 8.00384 | L-(-)-Malic acid for resolution of racemates for synthesis | 97-67-6 | 50g | $99.8 | 2024-03-01 | Buy |
Sigma-Aldrich | 8.00384 | L-(-)-Malic acid for resolution of racemates for synthesis | 97-67-6 | 500g | $411 | 2024-03-01 | Buy |
Sigma-Aldrich | 8.00384 | L-(-)-Malic acid for resolution of racemates for synthesis | 97-67-6 | 1kg | $801 | 2024-03-01 | Buy |
L-Malic acid Chemical Properties,Uses,Production
Description
L-Malic acid is nearly odorless (sometimes a faint, acrid odor) with a tart, acidic taste. It is nonpungent. May be prepared by hydration of maleic acid; by fermentation from sugars.
Chemical Properties
L-Malic acid is nearly odorless (sometimes a faint, acrid odor). This compound has a tart, acidic, nonpungent taste.
Chemical Properties
clear colourless solution
Occurrence
Occurs in maple sap, apple, melon, papaya, beer, grape wine, cocoa, sake, kiwifruit and chicory root.
Uses
The naturally occuring isomer is the L-form which has been found in apples and many other fruits and plants. Selective α-amino protecting reagent for amino acid derivatives. Versatile synthon for the preparation of chiral compounds including κ-opioid rece
Uses
L-Malic acid is used as a food additive, Selective α-amino protecting reagent for amino acid derivatives. Versatile synthon for the preparation of chiral compounds including κ-opioid receptor agonists, 1α,25-dihydroxyvitamin D3 analogue, and phoslactomycin B.
Uses
Intermediate in chemical synthesis. Chelating and buffering agent. Flavoring agent, flavor enhancer and acidulant in foods.
Preparation
L-Malic acid can be prepared by hydration of maleic acid; by fermentation from sugar.
Definition
ChEBI: An optically active form of malic acid having (S)-configuration.
General Description
L-Malic acid is an organic acid that is commonly found in wine. It plays an important role in wine microbiological stability.
Biochem/physiol Actions
L-Malic acid is a part of cellular metabolism. Its application is recognized in pharmaceutics. It is useful in the treatment of hepatic malfunctioning, effective against hyper-ammonemia. It is used as a part of amino acid infusion. L-Malic acid also serves as a nanomedicine in the treatment of brain neurological disorders. A TCA (Krebs cycle) intermediate and partner in the malic acid aspartate shuttle.
Purification Methods
Crystallise S-malic acid (charcoal) from ethyl acetate/pet ether (b 55-56o), keeping the temperature below 65o. Or dissolve it by refluxing in fifteen parts of anhydrous diethyl ether, decant, concentrate to one-third volume and crystallise it at 0o, repeatedly to constant melting point. [Beilstein 3 IV 1123.]
L-Malic acid Preparation Products And Raw materials
Raw materials
Preparation Products
1of3
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Jiangxi Alpha Hi-tech Pharmaceutical Co., Ltd | 510-85010237 | overseamarketing@alphahi-tech.com | CHINA | 41 | 58 |
Shanghai UCHEM Inc. | +862156762820 +86-13564624040 | sales@myuchem.com | China | 7121 | 58 |
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5866 | 58 |
Hebei Fengjia New Material Co., Ltd | +86-0311-87836622 +86-17333973358 | sales06@hbduling.cn | China | 8056 | 58 |
Anhui Ruihan Technology Co., Ltd | +8617756083858 | daisy@anhuiruihan.com | China | 994 | 58 |
Hebei Jingbo New Material Technology Co., Ltd | +8619931165850 | hbjbtech@163.com | China | 1000 | 58 |
Chongqing Zhihe Biopharmaceutical Co., Ltd. | +8618580541567 | sales@zhswyy.com | China | 303 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20293 | 58 |
airuikechemical co., ltd. | +undefined86-15315557071 | sales02@sdzhonghuimaterial.com | China | 983 | 58 |
Hebei Saisier Technology Co., LTD | +86-18400010335 +86-18034520335 | admin@hbsaisier.cn | China | 1009 | 58 |
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View Lastest Price from L-Malic acid manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-09-19 | L-Malic acid
97-67-6
|
US $30.00-10.00 / kg | 10kg | 99% | 100000kg | Hebei Chuanghai Biotechnology Co,.LTD | ||
2024-09-19 | L(-)-Malic acid
97-67-6
|
US $6.00 / kg | 1kg | 99% | 2000KG/Month | HebeiShuoshengImportandExportco.,Ltd | ||
2024-09-19 | L-Malic acid
97-67-6
|
US $0.00-0.00 / kg | 0.10000000149011612kg | 99% | 20tons | Chongqing Zhihe Biopharmaceutical Co., Ltd. |
- L-Malic acid
97-67-6
- US $30.00-10.00 / kg
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
- L(-)-Malic acid
97-67-6
- US $6.00 / kg
- 99%
- HebeiShuoshengImportandExportco.,Ltd
- L-Malic acid
97-67-6
- US $0.00-0.00 / kg
- 99%
- Chongqing Zhihe Biopharmaceutical Co., Ltd.