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D(+)-Malic acid

CAS No.
636-61-3
Chemical Name:
D(+)-Malic acid
Synonyms
D-MALIC ACID;(R)-MALIC ACID;D-(+)-MALIC ACID;(2R)-2-Hydroxybutanedioic acid;D-(+)-MaL;D(+)-Malic;D-APPLE ACID;(R)-malicaci;l(+)-malicaci;D-Aepfelsaeure
CBNumber:
CB9373789
Molecular Formula:
C4H6O5
Molecular Weight:
134.09
MDL Number:
MFCD00004245
MOL File:
636-61-3.mol
MSDS File:
SDS
Last updated:2024-03-28 13:39:29

D(+)-Malic acid Properties

Melting point 98-102 °C (lit.)
Boiling point 167.16°C (rough estimate)
alpha 2.2 º (c=3, H2O)
Density 1.60
refractive index 6.5 ° (C=10, Acetone)
storage temp. Store below +30°C.
solubility Soluble in methanol, ethanol, acetone, ether.
pka 3.61±0.23(Predicted)
form Crystalline Powder
color White
PH 2.2 (10g/l, H2O, 20℃)
optical activity [α]20/D +28.0±2°, c = 5.5% in pyridine
Water Solubility soluble
Merck 14,5707
BRN 1723540
LogP -1.370 (est)
CAS DataBase Reference 636-61-3(CAS DataBase Reference)
FDA UNII P750Y95K96
NIST Chemistry Reference (r)-Hydroxybutanedioic acid(636-61-3)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS05,GHS07
Signal word  Danger
Hazard statements  H315-H318-H335
Precautionary statements  P261-P280-P305+P351+P338
Hazard Codes  Xi
Risk Statements  37/38-41-36/37/38
Safety Statements  26-36-37/39
WGK Germany  3
RTECS  ON7260000
HS Code  29181980
NFPA 704
0
2 0

D(+)-Malic acid price More Price(45)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 02300 D-(+)-Malic acid unnatural form, ≥97.0% (T) 636-61-3 1g $34.02 2024-03-01 Buy
Sigma-Aldrich 8.00763 D-(+)-Malic acid for the resolution of racemates for synthesis 636-61-3 5G $120 2024-03-01 Buy
Sigma-Aldrich 46940-U D-Malic acid analytical standard 636-61-3 1kit $37 2024-03-01 Buy
Sigma-Aldrich 02300 D-(+)-Malic acid unnatural form, ≥97.0% (T) 636-61-3 5g $83.3 2024-03-01 Buy
TCI Chemical M0021 D-(+)-Malic Acid >98.0%(GC)(T) 636-61-3 5g $21 2024-03-01 Buy
Product number Packaging Price Buy
02300 1g $34.02 Buy
8.00763 5G $120 Buy
46940-U 1kit $37 Buy
02300 5g $83.3 Buy
M0021 5g $21 Buy

D(+)-Malic acid Chemical Properties,Uses,Production

Chemical Properties

white to light yellow crystal powde

Uses

D-(+)-Malic acid can be used:

  • As a starting material for the enantioselective total synthesis of (?)-erinapyrone B.
  • As a chiral organocatalyst in the synthesis of α-aminophosphonates from various aldehydes, aniline, and diethyl phosphite.

Uses

The naturally occuring isomer is the L-form which has been found in apples and many other fruits and plants. Selective α-amino protecting reagent for amino acid derivatives. Versatile synthon for the preparation of chiral compounds including κ-opioid rece

Uses

D-(+)-Malic acid used as an acidulant and flavoring agent, food additive. And it is also used in the place of the less sour citric acid in sour sweets.

Definition

ChEBI: An optically active form of malic acid having (R)-configuration.

Biological Activity

D-(+)-Malic acid, an active isomer of Malic acid, is a competitive inhibitor of L(--)malic acid transport.

Synthesis

Malic acid is isolated from immature apples; industrially prepared is obtained by catalytic oxidation of benzene, then reacting with water at high temperature and high pressure to generate maleic anhydride.

in vitro

Some bacteria belonging to Arthrobacter, Brevibacterium, Corynebacterium, Pseudomonas, Bacillus, and Acinetobacter produced D-(+)-Malic acid (D-Malic acid) from Maleic acid when the cells grown in a medium containing citraconic acid are reacted aerobically with Maleic acid in the pH 7.0 phosphate buffer containing 0.1% sodium chloride.

56-84-8
636-61-3
4198-33-8
6915-18-0
Synthesis of D(+)-Malic acid from L-Aspartic acid
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View Lastest Price from D(+)-Malic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
D( )Malic acid pictures 2024-04-26 D( )Malic acid
636-61-3
US $0.00-0.00 / KG 5KG 99% 500kg Speranza Chemical Co., Ltd.
D(+)-Malic acid pictures 2024-03-29 D(+)-Malic acid
636-61-3
US $0.00 / kg 1kg 99% 20tons Shaanxi TNJONE Pharmaceutical Co., Ltd
D(+)-Malic acid pictures 2023-09-13 D(+)-Malic acid
636-61-3
US $60.00-35.00 / kg 1kg 0.99 10 tons Hebei Yanxi Chemical Co., Ltd.
  • D( )Malic acid pictures
  • D( )Malic acid
    636-61-3
  • US $0.00-0.00 / KG
  • 99%
  • Speranza Chemical Co., Ltd.
  • D(+)-Malic acid pictures
  • D(+)-Malic acid
    636-61-3
  • US $0.00 / kg
  • 99%
  • Shaanxi TNJONE Pharmaceutical Co., Ltd
  • D(+)-Malic acid pictures
  • D(+)-Malic acid
    636-61-3
  • US $60.00-35.00 / kg
  • 0.99
  • Hebei Yanxi Chemical Co., Ltd.

D(+)-Malic acid Spectrum

Butanedioic acid, hydroxy-, (R)- hydroxy-,(R)-Butanedioicacid l(+)-malicaci (R)-(+)-MALIC ACID (+)-D-MALIC ACID D-(+)-APPLE ACID D-APPLE ACID MALIC ACID, D-(+)- (r)-hydroxybutanedioic acid (R)-(+)-HYDROXYSUCCINIC ACID (R)-HYDROXYSUCCINIC ACID (R)-2-HYDROXY-SUCCINIC ACID R(+)-2-HYDROXYSUCCINIC ACID (R)-2-HYDROXYBUTANEDICARBOXYLIC ACID D-MALIC ACID 100MG NEAT D-(+)-MALIC ACID 99% D-(+)-Malic acid, 98+% D-Aepfelsaeure D(+)-Malic Butanedioic acid, hydroxy-, (2R)- MALIC ACID, D-(+)-(P) D-MALIC ACID / (R)-(+)-HYDROXYSUCCINIC ACID D-HYDROXYBUTANEDIOIC ACID D-HYDROXYSUCCINIC ACID D-(+)-Malic acid ,99% D-(+)-Malic acid,(R)-(+)-2-Hydroxysuccinic acid, D-Hydroxybutanedioic acid D-(+)-MALIC ACID FOR THE RESOLUTION OF R (R)-(+)-2-Hydroxysuccinic acid, D-(+)-Malic acid, D-Hydroxybutanedioic acid (R)-(+)-2-Hydroxysuccinic acid, D-Hydroxybutanedioic acid (2R)-Malic acid D-(+)-2-Hydroxysuccinic acid [R,(+)]-2-Hydroxybutanedioic acid D-(+)-Malic acid unnatural forM, >=97.0% (T) D-(+)-Malic Acid, 97+% Butanedioic acid, 2-hydroxy-, (2R)- Malic Acid Impurity 3 (2R)-2-hydroxybutanedioate D-(+)-MalicAcid> D-(+)-MaL (R)-malicaci dextro-malic acid (R)-MALIC ACID D-MALIC ACID (2R)-2-Hydroxybutanedioic acid D-(+)-MALIC ACID (+)-Malic acid 636-61-3 480-40-4 Asymmetric Synthesis Optical Resolution Chiral Building Blocks Carboxylic Acids (Chiral) for Resolution of Bases Chiral Resolution Reagents Chiral Resolving Reagents Chiral Compound Aliphatics Chiral Reagents