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Diethyl malate

Diethyl malate structure

CAS No.: 7554-12-3

Chemical Name:: Diethyl malate

Synonyms: FEMA 2374;DIETHYL MALATE;ETHYL-DL-MALATE;DIETHYL DL-MALATE;Malic acid diethyl;DiethylDL-Malate>Diethyl hydroxysuccinate;Diethyl 2-hydroxysuccinate;DL-APPLE ACID DIETHYL ESTER;DL-MALIC ACID DIETHYL ESTER

CBNumber:: CB9418215

Molecular Formula:: C8H14O5

Molecular Weight:: 190.19

MDL Number:: MFCD00048556

MOL File:: 7554-12-3.mol

MSDS File:: SDS

Last updated:2023-11-28 16:31:43

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Diethyl malate Properties

Boiling point	122-124 °C12 mm Hg(lit.)
Density	1.128 g/mL at 25 °C(lit.)
refractive index	1.4330 to 1.4360
FEMA	2374 \| DIETHYL MALATE
Flash point	185 °F
storage temp.	Sealed in dry,Room Temperature
solubility	Chloroform (Sparingly), Ethyl Acetate (Slightly)
form	clear liquid
pka	12.35±0.20(Predicted)
color	Colorless to Light yellow
Odor	at 100.00 %. brown sugar sweet wine fruity herbal
Odor Type	caramellic
JECFA Number	620
Dielectric constant	10.2（18℃）
LogP	0.23
Substances Added to Food (formerly EAFUS)	DIETHYL MALATE
FDA 21 CFR	172.515
EWG's Food Scores	1
FDA UNII	59W97T99HI
EPA Substance Registry System	Butanedioic acid, hydroxy-, diethyl ester (7554-12-3)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H227

Precautionary statements

P501-P210-P280-P370+P378-P403+P235

WGK Germany

HS Code

2918.19.9000

NFPA 704

	2
0		0

Diethyl malate price More Price(11)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	W237418	Diethyl malate ≥97%, FG	7554-12-3	sample	$54.6	2024-03-01	Buy
Sigma-Aldrich	W237418	Diethyl malate ≥97%, FG	7554-12-3	1kg	$349	2024-03-01	Buy
TCI Chemical	M0024	Diethyl DL-Malate >98.0%(GC)	7554-12-3	25g	$30	2024-03-01	Buy
TCI Chemical	M0024	Diethyl DL-Malate >98.0%(GC)	7554-12-3	500g	$284	2024-03-01	Buy
Sigma-Aldrich	W237418	Diethyl malate ≥97%, FG	7554-12-3	100g	$81.9	2024-03-01	Buy

Product number	Packaging	Price	Buy
W237418	sample	$54.6	Buy
W237418	1kg	$349	Buy
M0024	25g	$30	Buy
M0024	500g	$284	Buy
W237418	100g	$81.9	Buy

Diethyl malate Chemical Properties,Uses,Production

Chemical Properties

Diethyl malate has a fruity odor with a pleasant herbaceous undertone. It is an ester of dicarboxylic acid

Occurrence

It exhibits two optically active isomers in addition to the optically inactive form; the most common is the l-isomer; reported present in the cultures of certain fungi (Rhizopus). Reported found in raspberry, cognac, malt whiskey, cider, sherry, white, red, port, sparkling, rose, strawberry and bilberry wines

Uses

Diethyl DL-Malate is used as a reagent in the synthesis of dicarboxylic nitroxyalkylamides and nitroxyalkylimides as anti-ischemic agents.

Preparation

The l-isomer can be prepared by esterification of the l-isomer of the acid with alcohol in the presence of HCl.

Definition

ChEBI: Diethyl malate is a malate ester obtained by the formal condensation of the two carboxy groups of malic acid with two molecules of ethanol respectively. It has a role as a metabolite.

Synthesis Reference(s)

Synthesis, p. 138, 1982 DOI: 10.1055/s-1982-29718

Diethyl malate synthesis

Synthesis of Diethyl malate from Thionyl chloride and YSAVZVORKRDODB-UHFFFAOYSA-N

Diethyl malate Preparation Products And Raw materials

Raw materials

L-Malic acid YSAVZVORKRDODB-UHFFFAOYSA-N Diethyl fumarate Water Levulinic acid

Ethanol 2-Methyltetrahydrofuran DL-Malic acid Furfural

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Preparation Products

Diethyl malate Suppliers

Global( 83)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12456	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Shaanxi Dideu Medichem Co. Ltd	18192627656	1012@dideu.com	China	3371	58
Antai Fine Chemical Technology Co.,Limited	18503026267	info@antaichem.com	CHINA	9641	58
Hefei TNJ Chemical Industry Co.,Ltd.	0551-65418671	sales@tnjchem.com	China	34572	58
ANHUI WITOP BIOTECH CO., LTD	+8615255079626	eric@witopchemical.com	China	23556	58
Xi'an MC Biotech, Co., Ltd.	029-89275612 +8618991951683	mcbio_sales@163.com	China	2255	58
Dayang Chem (Hangzhou) Co.,Ltd.	571-88938639 +8617705817739	info@dycnchem.com	CHINA	52867	58
Changzhou Anxuan Chemical Co., Ltd	+86-0519-89882563 +86-18961279162	andy@anxuanchem.com	China	4226	58
Hebei Guanlang Biotechnology Co., Ltd.	+86-19930503259 +86-19930503259	cherry@crovellbio.com	China	18455	58

Supplier	Advantage
Hebei Mojin Biotechnology Co., Ltd	58
Hubei Jusheng Technology Co.,Ltd.	58
Shaanxi Dideu Medichem Co. Ltd	58
Antai Fine Chemical Technology Co.,Limited	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
ANHUI WITOP BIOTECH CO., LTD	58
Xi'an MC Biotech, Co., Ltd.	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Changzhou Anxuan Chemical Co., Ltd	58
Hebei Guanlang Biotechnology Co., Ltd.	58

View Lastest Price from Diethyl malate manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2023-09-23	Diethyl malate 7554-12-3	US $0.00 / KG	1KG	99%	50000KG/month	Hebei Mojin Biotechnology Co., Ltd
2023-09-06	Diethyl malate 7554-12-3	US $0.00-0.00 / KG	1KG	99%	500000kg	Hebei Guanlang Biotechnology Co., Ltd.
2020-03-16	Diethyl DL-Malate 7554-12-3	US $1.00-0.00 / KG	1KG	99%	50 tons	Shaanxi Dideu Medichem Co. Ltd

Diethyl malate
7554-12-3
US $0.00 / KG
99%
Hebei Mojin Biotechnology Co., Ltd

Diethyl malate
7554-12-3
US $0.00-0.00 / KG
99%
Hebei Guanlang Biotechnology Co., Ltd.

Diethyl DL-Malate
7554-12-3
US $1.00-0.00 / KG
99%
Shaanxi Dideu Medichem Co. Ltd

Diethyl malate Spectrum

Diethyl malate(7554-12-3)¹HNMR Diethyl malate(7554-12-3)FT-IR

7554-12-3(Diethyl malate)Related Search:

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Succimer Diethyl phthalate Diethyl sulfate Tris(trimethylsilyl)phosphate Malic acid

Diethyl oxalate DIETHYL PHOSPHATE Succinic acid

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2-hydroxy-butanedioicaciddiethylester Butanedioicacid,hydroxy-,diethylester hydroxy-butanedioicacidiethylester FEMA 2374 ETHYL-DL-MALATE DIETHYL MALATE DIETHYL DL-MALATE DL-MALIC ACID DIETHYL ESTER DL-APPLE ACID DIETHYL ESTER DL-MALIC ACID DIETHYL ESTER 98+% diethylmalate,hydroxy-butanedioicacid,diethylester Hydroxybutanedioic acid diethyl ester Diethyl hydroxysuccinate Hydroxysuccinic acid diethyl ester Malic acid diethyl Butanedioic acid, 2-hydroxy-, 1,4-diethyl ester DL-Apple Acid Diethyl Ester DL-Malic Acid Diethyl Ester Diethyl 2-hydroxysuccinate Diethyl DL-Malate DiethylDL-Malate> ethyl 4-ethoxy-2-hydroxy-4-oxobutanoate 7554-12-3 7554-12-03 C2H5OCOCH2CHOHCOOC2H5 C2H5OOCCHOHCH2COOC2H5