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Lipid soluble surface anaesthetic Uses Methods of production Chemical property

CAS No.94-09-7
Chemical Name:Benzocaine
Synonyms:Solu H;Norcain;Ora-jel;ORTHESIN;Ethoform;Norcaine;Topcaine;Euphagin;NSC 4688;AETHOFORM
Molecular Formula:C9H11NO2
Formula Weight:165.19
MOL File:94-09-7.mol
Benzocaine Property
Melting point : 88-90 °C
Boiling point : 172 °C (12.7517 mmHg)
density : 1.17
Fp : 172°C/13mm
storage temp. : 0-6°C
Water Solubility : Soluble in ethanol, chloroform, ethyl ether and dilute acids. Sparingly soluble in water
Merck : 14,1086
BRN : 638434
Stability:: Stable. Combustible. Incompatible with strong oxidizing agents.
CAS DataBase Reference: 94-09-7(CAS DataBase Reference)
NIST Chemistry Reference: Benzoic acid, 4-amino-, ethyl ester(94-09-7)
EPA Substance Registry System: Benzoic acid, 4-amino-, ethyl ester(94-09-7)
Hazard Codes : Xi,T,F
Risk Statements : 43-36/37/38-39/23/24/25-23/24/25-11
Safety Statements : 22-24/25-37/39-26-24-45-36/37-16-7
WGK Germany : 2
RTECS : DG2450000
TSCA : Yes
PackingGroup : III
HS Code : 29224995
Hazardous Substances Data: 94-09-7(Hazardous Substances Data)

Benzocaine Chemical Properties,Usage,Production

Lipid soluble surface anaesthetic
Benzocaine is a fat soluble surface anaesthetic. Compared with several other local anesthetics such as lidocaine, tetracaine, etc., the strength of effect is small. Owing to its playing role in mucosal, people feel comfort. It is a fat soluble and strong drug, therefore it is easy to combine with the lipid layer of the mucosa or skin, but not easily go through the human body to produce toxic.
Benzocaine is the precursor materials of Ousso imitation, Orthocaine, procaine. At the same time, it is used as a local anesthetic in medicine, and has analgesic, antipruritic effect, mainly used for wounds, ulcers, mucosal surfaces and hemorrhoids narcotic pain and itch. The ointment can also be used for relieving pain and lubrication to nasopharyngeal catheter and the process of PEEP mirror. Temporary relieve pain and itching skin in the wounds of mild burns, sunburn, trauma and insect bites. Ears are used to reduce the pain and itching of acute congestive, concentrated otitis, swimming, and external use. Also it is effective to toothache, sore throat, oral ulcers, hemorrhoids, anal fissure, vulva Sao. As Male Genital Desensitizer make ejaculation slow. Or used as a lubricant for the anesthesia of the catheter and the endoscope.
1.The goods are used to relieve pain for the local anesthetic, wounds, ulcers and hemorrhoids facial, also are cough suppressants retreat intermediates.
2.Used in cosmetic ultraviolet absorption, local anesthetics and used to relieve pain in the wound, ulcer surface and Hemorrhoids.
Methods of production
The goods are got in the way that p-Nitro-ethylbenzoate is reduced by iron [99-77-4].
Chemical property
It is Colorless oblique square crystal. Melting point is 92℃ (88-90℃), boiling point is 183-184 (1.87kPa). 1g of the product is soluble in water, 5ml ethanol, 2ml, 4ml, 2500ml, 30-50ML, or almond oil and olive oil, also soluble in dilute acid. Stable in the air, no smell, taste bitter.
Chemical Properties
white odourless crystals
A commonly used topical pain reliever. Main active ingredient in anesthetic ointments.
Anesthetic;Na+ channel blocker
Benzocaine is used as an anesthetic (local).
Benzocaine Preparation Products And Raw materials
Raw materials
4-Aminobenzoic acid Ethyl p-nitrobenzoate 4-Aminophthalic acid
Preparation Products
Benzonatate 4-Fluorobenzoic acid Ethyl 4-(butylamino)benzoate
Benzocaine Suppliers      Global( 341)Suppliers     
Changzhou Sunlight Pharmaceutical Co., Ltd +86-519-83131668 ; 83137042;83139028;83138042+86-519-83138041info@sunlightchem.comChina 99 69
Chengdu XiYa Chemical Technology Co., Ltd. 4008-626-111028-84752058sale@xiyashiji.comChina 9747 57
Shanghai Everchem Co., Ltd 86-29-81325371+86-29-81325373info@everchem.cnChina 88 62
Changzhou Sunchem Pharmaceutical Chemical Material Co.,Ltd. 0519-85269522;13660798926013660798926850311@sunkechem.comChina 100 60
iFar Chemical Technology +86-510-83488850; 78 50
Changzhou Sunlight Farmacéutica.S.L. 0519-83138357,137061217220519-83138041810308@sunlightchem.comChina 48 60
Changzhou Yonghe Fine Chemical Co., Ltd. 0519-88552298;1392108697886-519-88552298xuxiaosong1972@163.comChina 47 65
WuHan YuanCheng Gongchuang Technology Co.Ltd 027-88211053/290027-88608190-969gy08@yccreate.comChina 2881 55
J & K SCIENTIFIC LTD. 400-666-7788;market6@jkchemical.comChina 96832 76
Changzhou Sunchem Pharmaceutical Chemical Material Co., Ltd +86-519-85195575; 85195565; 15861192208+86-519-85195585info@sunkechem.comChina 111 69
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