ChemicalBook >> CAS DataBase List >>5-Aminofluorescein

5-Aminofluorescein

CAS No.
3326-34-9
Chemical Name:
5-Aminofluorescein
Synonyms
5-AF;FLUORESCEINAMINE;5-AFM;AMINOFLUORESCEIN;4-AMINOFLUORESCEIN;(isoMer I);5-AMINOFLUORESCEIN;1-AMINOFLUORESCEIN;1-FLUORESCEINAMINE;Fluoresceinamine I
CBNumber:
CB3254491
Molecular Formula:
C20H13NO5
Molecular Weight:
347.32
MDL Number:
MFCD00005052
MOL File:
3326-34-9.mol
Last updated:2024-04-24 17:21:45

5-Aminofluorescein Properties

Melting point 223 °C (dec.)(lit.)
Boiling point 481.89°C (rough estimate)
Density 1.3724 (rough estimate)
refractive index 1.5180 (estimate)
storage temp. room temp
solubility DMF: 5 mg/ml; DMSO: 5 mg/ml
form powder
pka 9.34±0.20(Predicted)
color red-brown
Water Solubility Soluble in water (partly), methanol (10 mg/ml), and acetone.
BRN 48395
Stability Light and Moisture Sensitive
InChIKey GZAJOEGTZDUSKS-UHFFFAOYSA-N
CAS DataBase Reference 3326-34-9(CAS DataBase Reference)
FDA UNII YY8M286SWU
EPA Substance Registry System Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 5-amino-3',6'-dihydroxy- (3326-34-9)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P264-P270-P301+P312-P302+P352-P305+P351+P338
Hazard Codes  Xn
Risk Statements  22-36/37/38
Safety Statements  26
WGK Germany  3
10
TSCA  Yes
HS Code  32049090
NFPA 704
0
2 0

5-Aminofluorescein price More Price(38)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 201626 Fluoresceinamine, isomer I 3326-34-9 1g $171 2024-03-01 Buy
Sigma-Aldrich 201626 Fluoresceinamine, isomer I 3326-34-9 5g $636 2024-03-01 Buy
TCI Chemical A0306 5-Aminofluorescein (isomer I) >95.0%(HPLC)(T) 3326-34-9 1g $164 2024-03-01 Buy
TCI Chemical A0306 5-Aminofluorescein (isomer I) >95.0%(HPLC)(T) 3326-34-9 5g $514 2024-03-01 Buy
Alfa Aesar J62175 Fluoresceinamine, isomer I, 96% 3326-34-9 1g $135 2024-03-01 Buy
Product number Packaging Price Buy
201626 1g $171 Buy
201626 5g $636 Buy
A0306 1g $164 Buy
A0306 5g $514 Buy
J62175 1g $135 Buy

5-Aminofluorescein Chemical Properties,Uses,Production

Chemical Properties

Dark Red Solid

Uses

5-aminofluorescein is also used to prepare FITC Isomer I (CDX-F0011, CDX-F0020). It is a chemical used as molecular probe and important as fluorescent dye and for derivatives. Fluorescent labeling reagent for proteins. Used in the fluorescent antibody technique for rapid identification of pathogens.

Uses

Glycosaminoglycuronans react with 5-aminofluorescein to yield fluorescent derivatives. 5-aminofluorescein is also used to prepare FITC Isomer I (F-011, F-020).

Definition

ChEBI: 5-aminofluorescein is a primary amino compound that is fluorescein carrying an amino substituent at C-5. Building block/intermediate for the synthesis of the fluorescent dye flourescein; also used to produce N-(fluorescein-5-yl)maleamic acid. It derives from a fluorescein (lactone form).

Preparation

The preparation of 5-aminofluorescein is carried out either by first saponification of 5-nitrofluorescein acetates with alcohol alkali, followed by reduction of the obtained 5-nitrofluorescein in a solution of alcohol alkali with hydrazine hydrate on a nickel catalyst to obtain 5-aminofluorescein , Or by boiling in an aqueous solution of sodium sulfide. The restoration of the nitro group and the saponification of acetates in the second case occurs in one stage.

General Description

Fluoresceinamine, isomer I belongs to the class of derivatized fluoresceins.

5434-21-9
108-46-3
3326-34-9
Synthesis of 5-Aminofluorescein from 4-Aminophthalic acid and Resorcinol

5-Aminofluorescein Preparation Products And Raw materials

Global( 212)Suppliers
Supplier Tel Email Country ProdList Advantage
Hongxiong
+undefined18915499068 Suzhouhongxiong@163.com China 120 58
Hebei Mojin Biotechnology Co., Ltd
+8613288715578 sales@hbmojin.com China 12456 58
Ouhuang Engineering Materials (Hubei) Co., Ltd
+8617702722807 admin@hbouhuang.com China 2259 58
Springchem New Material Technology Co.,Limited
+86-021-62885108 +8613917661608 info@spring-chem.com China 2068 57
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29797 60
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32480 60
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
Changzhou Ansciep Chemical Co., Ltd.
+86 519 86305871 sales@ansciepchem.com CHINA 4242 58
Accela ChemBio Inc.
(+1)-858-699-3322 info@accelachem.com United States 19965 58
Hebei Guanlang Biotechnology Co., Ltd.
+86-19930503282 alice@crovellbio.com China 8823 58

View Lastest Price from 5-Aminofluorescein manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
5-Aminofluorescein pictures 2024-04-24 5-Aminofluorescein
3326-34-9
US $1.00 / KG 1KG 99.91% 200000 Ouhuang Engineering Materials (Hubei) Co., Ltd
5-Aminofluorescein pictures 2023-06-30 5-Aminofluorescein
3326-34-9
US $0.00 / KG 1KG 99% 50000KG/month Hebei Mojin Biotechnology Co., Ltd
5-Aminofluorescein pictures 2023-03-01 5-Aminofluorescein
3326-34-9
US $20.00 / kg 1kg 99% 5000 Ton Hebei Duling International Trade Co. LTD
  • 5-Aminofluorescein pictures
  • 5-Aminofluorescein
    3326-34-9
  • US $1.00 / KG
  • 99.91%
  • Ouhuang Engineering Materials (Hubei) Co., Ltd
5-Amino-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-(9H)xanthen]-3-one Fluoresceinamine 5-amino-3',6'-dihydroxy-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one FLUORESCEINAMINE ISOMER I FLUORESCEINAMINE, ISOMER 1 5-amino-2-(3-hydroxy-6-oxoxanthen-9-yl)benzoic acid 5-AMINO-3',6'-DIHYDROXYSPIRO[ISOBENZOFURAN-1(3H),9'-(9H)XANTHEN]-3-ONE 5-AMINOFLUORESCEIN ISOMER I 5-AMINOFLUORESCEIN 4-AMINOFLUORESCEIN ISOMER I 1-FLUORESCEINAMINE 1-AMINOFLUORESCEIN 9’-[9h]xanthen]-3-one,5-amino-3’,6’-dihydroxy-spiro[isobenzofuran-1(3h Fluoresceinamine,isomerⅡ 5-AMINOFLUORESCEIN, FOR FLUORESCENCE FLUORESCEIN AMINE ISOMER I 99% 4-AMINOFLUORESCEIN (ISOMER 1) Fluoresceinamine isomer I, pure FLUORESCENAMINEISOMERI 6-Amino-3',6'-dihydroxyspiro[2-benzofuran-3,9'-xanthene]-1-one Fluoresceinamine I Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 5-amino-3',6'-dihydroxy- 3,6-Dihydroxy-5'-aminospiro[9H-xanthene-9,1'(3'H)-isobenzofuran]-3'-one (isoMer I) 5-AMinofluorescein  FluoresceinaMine isoMer I, pure 1GR FluoresceinaMine isoMer I, pure 5GR Fluoresceinamine, isomer I,5-Aminofluorescein 5-Fluoresceinamine isomer I 5-Aminofluorescein (isomer I)> 5-Aminofluorescein (5-AF) 5-amino-3',6'-dihydroxy-3H-spiro[2-benzofuran-1, 9'-xanthen]-3-one FLUORESCEINAMINE 4-AMINOFLUORESCEIN 5-AFM AMINOFLUORESCEIN 5-AF *Desflurane Impurity 6 (Desflurane EP Impurity F) 5-Amino-3',6'-dihydroxy-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one 3326-34-9 C20H13O5 C20H13NO5 Biochemicals and Reagents BioChemical Detection Fluorescein and Derivatives Fluorescent Labels Fluorescent Probes, Labels, Particles and Stains marker Fluorescent Labels and Indicators Fluorescent Labels & Indicators