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Amlodipine besilate

CAS No.111470-99-6
Chemical Name:Amlodipine besilate
Synonyms:Amlor;Amcard;Lowrac;Norvas;Vazkor;NORVASC;Amdepin;Amdipin;Amlodin;Amlopin
CBNumber:CB4127875
Molecular Formula:C26H31ClN2O8S
Formula Weight:567.05
MOL File:111470-99-6.mol
Amlodipine besilate Property
mp : 199-201°C
storage temp. : Store at RT
solubility : DMSO: 20 mg/mL
form : solid
color : white
CAS DataBase Reference: 111470-99-6(CAS DataBase Reference)
Safety
Hazard Codes : Xn
Risk Statements : 22-36/37/38-20/21/22
Safety Statements : 26-36
WGK Germany : 3
RTECS : US7967700
Hazardous Substances Data: 111470-99-6(Hazardous Substances Data)

Amlodipine besilate Chemical Properties,Usage,Production

Chemical Properties
White Crystalline Solid
Usage
A dihydropyridine calcium channel blocker. Used as an antianginal and antihypertensive
Usage
Angiotensin II inhibitor prodrug, antihypertensive
Biological Activity
L-type calcium channel blocker that displays antihypertensive properties. Inhibits Ca 2+ -induced contractions in depolarized rat aorta (IC 50 = 1.9 nM) and displays vasoprotective effects in cardiovascular disease. Inhibits proliferation of human vascular smooth muscle cells and epidermoid carcinoma A431 cells (IC 50 = 25 μ M).
Amlodipine besilate Preparation Products And Raw materials
Raw materials
Preparation Products
Amlodipine besilate Suppliers      Global( 179)Suppliers     
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Shanghai Boyle Chemical Co., Ltd. Ms Xu:+86-21-50180596;Miss Zhang:021-50185988;Mr Qiu:021-50182298+86-21-57758967sales@boylechem.comCHINA 10038 55
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833+86-10-82849933jkinfo@jkchemical.com;market3@jkchemical.comCHINA 96863 76
Meryer (Shanghai) Chemical Technology Co., Ltd. +86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-62670440(Beijing)+86-(0)21-61259102(Shanghai) +86-(0)755-86170066(ShenZhen) +86-(0)10-62670790(Beijing)sh@meryer.com; sz@meryer.comCHINA 40414 62
INTATRADE GmbH +49 3493/605464+49 3493/605470sales@intatrade.deGERMANY 3701 66
3B Pharmachem (Wuhan) International Co.,Ltd. 86-21-50328103 * 801、803、804、807 Mobile:1893055203786-21-503281093bsc@sina.comCHINA 15991 69
TCI (Shanghai) Development Co., Ltd. 800-988-0390021-67121385sales@tcishanghai.com.cnCHINA 22161 81
BeiJing Hwrk Chemicals Limted 4006990298 010-57411839 020-31335234 021-51691807010-87653215 0757-86311057 021-55236763sales@hwrkchemical.comCHINA 13318 55
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Development of Beijing Chemical Technology Co.,Ltd. 010-69755668; 57131961 ; 62507480010-69755668ZKTZFDC168@hotmail.comCHINA 3540 54
400-600-9262021-51701678mc@titansci.comCHINA 13102 59
 
111470-99-6(Amlodipine besilate)Related Search:
Azabenzene Benzenesulfonic acid AMLODIPINE BESILATE IMP.D (EP): 3-ETHYL-5-METHYL 2-[(2-AMINOETHOXY)METHYL]-4-(2-CHLOROPHENYL)-6-METHYLPYRIDINE-3,5-DICARBOXYLATE Amlodipine (S)-Amlodipine Amlodipine mesylate Amlodipine besilate
2-[(2-AMINOETHOXY)-METHYL]-4-(2-CHLOROPHENYL)-1,4-DIHYDRO-6-METHYL-3,5-PYRIDINEDICARBOXYLIC ACID 3-ETHYL 5-METHYL ESTER BENZENE SULFONATE 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine benzenesulfonate 111470-99-6 Cell Signaling and Neuroscience Calcium Channel Modulators Cell Biology BioChemical AMLODIPINE BENZENESULFONATE AMLODIPINE BESILATE AMLODIPINE BESYLATE NORVASC Ion Channels Inhibitors and Activators Voltage-gated Ion Channels 3,5-pyridinedicarboxylicacid,2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-1, 4-dihydro-6-methyl-,3-ethyl-5-methylester,monobenzenesulfonate AMLODIPINE BESILATE MM(CRM STANDARD) AMLODIPINE BESYLATE EPY(CRM STANDARD) C20H25ClN2O5C6H6O3S 11470-99-6 2-[(2-aminoethoxy)-methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl ester benzene sulfonate AMLODIPINEBESYLATE(SUBJECTTOPATENTFREE) (+-)-3-Ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate monobenzenesulfonate 3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester, monobenzenesulfonate Amcard Amdepin Amdipin Amlodin Amlopin Amlor Amlosyn Antacal Benzenesulfonic acid, compd. with 3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate (1:1) Calchek Lowrac Monopina Norvas Norvask Tensivask UK 48340-26 C26H31ClN2O8S Active Pharmaceutical Ingredients 2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine benzenesulfonate Ethyl 2-[(2-aminoethoxy)methyl]-4-(2-chloropohenyl)-1,4-dihydro-5-(methoxycarbonyl)-6-methylpyridine-3-carboxylate benzenesulphonate Dihydropyridine Class Chemicals Intermediates & Fine Chemicals Pharmaceuticals Amlodipine 2-(2-Aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylic acid 3-ethyl=5-methyl·benzenesulfonic acid C20H25ClN2O5C6H5SO3H Aromatics Dihydropyridine Heterocycles 111470-99-6 Amlodipine Besylate (350 mg) Vazkor 3-Ethyl 5-Methyl 2-(2-Aminoethoxy)methyl-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate Benzenesulfonate 2-(2-Aminoethoxy)methyl-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylic Acid 3-Ethyl 5-Methyl Ester Benzenesulfona 3-ethyl 5-Methyl 2-((2-aMinoethoxy)Methyl)-4-(2-chlorophenyl)-6-Methyl-1,4-dihydropyridine-3,5-dicarboxylate benzenesulfonate
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