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Amlodipine Besylate

Description References
Amlodipine Besylate
Amlodipine Besylate
Chemical Name:
Amlodipine Besylate
Molecular Formula:
Formula Weight:
MOL File:

Amlodipine Besylate Properties

Melting point:
storage temp. 
Store at RT
DMSO: 20 mg/mL
Water Solubility 
Soluble in DMSO (20 mg/mL), water (10 mM), chloroform, ethanol (14 mg/mL), and methanol.
CAS DataBase Reference
111470-99-6(CAS DataBase Reference)
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xn
Risk Statements  22-36/37/38-20/21/22
Safety Statements  26-36
WGK Germany  3
RTECS  US7967700
Hazardous Substances Data 111470-99-6(Hazardous Substances Data)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.
P501 Dispose of contents/container to..…

Amlodipine Besylate price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich A5605 Amlodipine besylate ≥98% (HPLC) 111470-99-6 10mg $134 2017-11-08 Buy
Sigma-Aldrich 1029501 Amlodipine besylate United States Pharmacopeia (USP) Reference Standard 111470-99-6 350mg $348.4 2017-11-08 Buy
TCI Chemical A2353 Amlodipine Besylate >98.0%(HPLC)(N) 111470-99-6 1g $71 2017-11-08 Buy
TCI Chemical A2353 Amlodipine Besylate >98.0%(HPLC)(N) 111470-99-6 5g $239 2017-11-08 Buy
Alfa Aesar J62164 Amlodipine besylate, 98+% 111470-99-6 1g $113 2017-11-08 Buy

Amlodipine Besylate Chemical Properties,Uses,Production


Amlodipine (generic name Amlodipine Besylate) is a class of calcium channel blockers. One of the amlodipine product on the market is Norvasc®.
Amlodipine functionalizes by the dilation of blood vessels and the improvement of blood flow, which lead to lowered blood pressure. Thereby, it is used to treat high bold pressure (hypertension). Lowering high blood pressure also reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions, and kidney problems. Amlodipine is also used to prevent certain types of chest pains (angina), which may help to increase the ability to exercise and decrease the frequency of angina attacks. Amlodipine can be used to treat coronary artery disease (CAD) including chronic stable angina, vasospastic angina, and angiographically documented CAD.



Chemical Properties

White Crystalline Solid


A dihydropyridine calcium channel blocker. Used as an antianginal and antihypertensive


Angiotensin II inhibitor prodrug, antihypertensive


Amlodipine besylate is a L-type calcium channel blocker which may be used for the treatment of angina pectoris and hypertension. Amlodipine also inhibits growth of human epidermoid carcinoma A431 cells and has antireproductive effects in male rats.


ChEBI: The benzenesulfonate salt of amlodipine.

Biological Activity

L-type calcium channel blocker that displays antihypertensive properties. Inhibits Ca 2+ -induced contractions in depolarized rat aorta (IC 50 = 1.9 nM) and displays vasoprotective effects in cardiovascular disease. Inhibits proliferation of human vascular smooth muscle cells and epidermoid carcinoma A431 cells (IC 50 = 25 μ M).

Amlodipine Besylate Preparation Products And Raw materials

Raw materials

Preparation Products

Amlodipine Besylate Suppliers

Global( 289)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 CHINA 3229 55
Rixing Chemical CO.,LTD
- CHINA 233 55
Henan Tianfu Chemical Co.,Ltd.
0371-55170693 CHINA 20811 55
Shanghai Time Chemicals CO., Ltd.
+86-021-57951555 CHINA 1374 55
Boen pharm 86 512-62572107 62962707
86 512-62922078 China 803 58
Shenzhen Simeiquan Biotechnology Co. Ltd 18126413629 0755-23311925 QQ2355327053
0755-23311925 China 5255 58
Wuhan HongxinKang Fine Chemical Co., Ltd. 18672345876
027-59721024 China 1883 58
Foshan DaoQi Biological Co., Ltd. 18038709069
0757-38709069 China 4175 58
Foshan DaoQi Biological Co., Ltd. 0757-86287544 18038709356
0757-86287544 CHINA 3020 58
Shanghai Boyle Chemical Co., Ltd. 86-15221043597
86-21-57758967 China 2861 55

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