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Amlodipine besilate

CAS No.111470-99-6
Chemical Name:Amlodipine besilate
Synonyms:Amlor;Amcard;Lowrac;Norvas;Vazkor;NORVASC;Amdepin;Amdipin;Amlodin;Amlopin
CBNumber:CB4127875
Molecular Formula:C26H31ClN2O8S
Formula Weight:567.05
MOL File:111470-99-6.mol
Amlodipine besilate Property
mp : 199-201°C
storage temp. : Store at RT
solubility : DMSO: 20 mg/mL
form : solid
color : white
CAS DataBase Reference: 111470-99-6(CAS DataBase Reference)
Safety
Hazard Codes : Xn
Risk Statements : 22-36/37/38-20/21/22
Safety Statements : 26-36
WGK Germany : 3
RTECS : US7967700
Hazardous Substances Data: 111470-99-6(Hazardous Substances Data)

Amlodipine besilate Chemical Properties,Usage,Production

Chemical Properties
White Crystalline Solid
Usage
A dihydropyridine calcium channel blocker. Used as an antianginal and antihypertensive
Usage
Angiotensin II inhibitor prodrug, antihypertensive
Usage
Amlodipine besylate is a L-type calcium channel blocker which may be used for the treatment of angina pectoris and hypertension. Amlodipine also inhibits growth of human epidermoid carcinoma A431 cells and has antireproductive effects in male rats.
Biological Activity
L-type calcium channel blocker that displays antihypertensive properties. Inhibits Ca 2+ -induced contractions in depolarized rat aorta (IC 50 = 1.9 nM) and displays vasoprotective effects in cardiovascular disease. Inhibits proliferation of human vascular smooth muscle cells and epidermoid carcinoma A431 cells (IC 50 = 25 μ M).
Amlodipine besilate Preparation Products And Raw materials
Raw materials
Preparation Products
Amlodipine besilate Suppliers      Global( 182)Suppliers     
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Shanghai Boyle Chemical Co., Ltd. Mr Qiu:021-50182298;Ms Xu:+86-21-50180596;Miss Zhang:021-50185988+86-21-57758967sales@boylechem.comCHINA 10052 55
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111470-99-6(Amlodipine besilate)Related Search:
Azabenzene Benzenesulfonic acid AMLODIPINE BESILATE IMP.D (EP): 3-ETHYL-5-METHYL 2-[(2-AMINOETHOXY)METHYL]-4-(2-CHLOROPHENYL)-6-METHYLPYRIDINE-3,5-DICARBOXYLATE Amlodipine (S)-Amlodipine Amlodipine mesylate Amlodipine besilate
2-[(2-AMINOETHOXY)-METHYL]-4-(2-CHLOROPHENYL)-1,4-DIHYDRO-6-METHYL-3,5-PYRIDINEDICARBOXYLIC ACID 3-ETHYL 5-METHYL ESTER BENZENE SULFONATE 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine benzenesulfonate 111470-99-6 Cell Signaling and Neuroscience Calcium Channel Modulators Cell Biology BioChemical AMLODIPINE BENZENESULFONATE AMLODIPINE BESILATE AMLODIPINE BESYLATE NORVASC Ion Channels Inhibitors and Activators Voltage-gated Ion Channels 3,5-pyridinedicarboxylicacid,2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-1, 4-dihydro-6-methyl-,3-ethyl-5-methylester,monobenzenesulfonate AMLODIPINE BESILATE MM(CRM STANDARD) AMLODIPINE BESYLATE EPY(CRM STANDARD) C20H25ClN2O5C6H6O3S 11470-99-6 2-[(2-aminoethoxy)-methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl ester benzene sulfonate AMLODIPINEBESYLATE(SUBJECTTOPATENTFREE) (+-)-3-Ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate monobenzenesulfonate 3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester, monobenzenesulfonate Amcard Amdepin Amdipin Amlodin Amlopin Amlor Amlosyn Antacal Benzenesulfonic acid, compd. with 3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate (1:1) Calchek Lowrac Monopina Norvas Norvask Tensivask UK 48340-26 C26H31ClN2O8S Active Pharmaceutical Ingredients 2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine benzenesulfonate Ethyl 2-[(2-aminoethoxy)methyl]-4-(2-chloropohenyl)-1,4-dihydro-5-(methoxycarbonyl)-6-methylpyridine-3-carboxylate benzenesulphonate Dihydropyridine Class Chemicals Intermediates & Fine Chemicals Pharmaceuticals Amlodipine 2-(2-Aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylic acid 3-ethyl=5-methyl·benzenesulfonic acid C20H25ClN2O5C6H5SO3H Aromatics Dihydropyridine Heterocycles 111470-99-6 Amlodipine Besylate (350 mg) Vazkor 3-Ethyl 5-Methyl 2-(2-Aminoethoxy)methyl-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate Benzenesulfonate 2-(2-Aminoethoxy)methyl-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylic Acid 3-Ethyl 5-Methyl Ester Benzenesulfona 3-ethyl 5-Methyl 2-((2-aMinoethoxy)Methyl)-4-(2-chlorophenyl)-6-Methyl-1,4-dihydropyridine-3,5-dicarboxylate benzenesulfonate
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