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2,4'-Dibromoacetophenone

2,4'-Dibromoacetophenone Structure
2,4'-Dibromoacetophenone structure
CAS No.
99-73-0
Chemical Name:
2,4'-Dibromoacetophenone
Synonyms
99-73-0;2-BROMO-1-(4-BROMOPHENYL)ETHAN-1-ONE;PBPB;2-BROMO-1-(4-BROMOPHENYL)ETHANONE;P-BROMOPHENACYL BROMIDE;4-BROMOPHENACYL BROMIDE;p-bromophenacyl-8;AKOS BBS-00000865;GSK-3β Inhibitor VII;BromophenacylBromide
CBNumber:
CB4239093
Molecular Formula:
C8H6Br2O
Molecular Weight:
277.94
MDL Number:
MFCD00000200
MOL File:
99-73-0.mol
MSDS File:
SDS
Last updated:2023-08-31 16:33:09
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2,4'-Dibromoacetophenone Properties

Melting point 108-110 °C(lit.)
Boiling point 1415°C/760mm
Density 1.7855 (rough estimate)
refractive index 1.5560 (estimate)
storage temp. Store below +30°C.
solubility DMF: 5 mg/ml; DMSO: 2 mg/ml; Ethanol: 1 mg/ml; PBS (pH 7.2): insol
form Crystalline Solid
color Slightly yellow to beige
Water Solubility Soluble in dimethyl sulfoxide (5 mg/ml), methanol (20 mg/ml), toluene and ethanol. Insoluble in water.
Sensitive Lachrymatory
Merck 14,1427
BRN 607604
Stability Stable. Incompatible with strong bases, strong reducing agents, strong oxidizing agents.
InChIKey FKJSFKCZZIXQIP-UHFFFAOYSA-N
CAS DataBase Reference 99-73-0(CAS DataBase Reference)
FDA UNII PN0FRW1G4Z
EPA Substance Registry System Ethanone, 2-bromo-1-(4-bromophenyl)- (99-73-0)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS05
Signal word  Danger
Hazard statements  H314
Precautionary statements  P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363
Hazard Codes  C
Risk Statements  34
Safety Statements  26-36/37/39-45
RIDADR  UN 3261 8/PG 2
WGK Germany  2
RTECS  AM6950000
F  19-21
Hazard Note  Corrosive/Lachrymatory
TSCA  T
HazardClass  8
PackingGroup  III
HS Code  29147090
NFPA 704
0
3 0

2,4'-Dibromoacetophenone price More Price(38)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 68082 2,4′-Dibromoacetophenone for HPLC derivatization, ≥99.0% (HPLC) 99-73-0 5g $78.3 2024-03-01 Buy
Sigma-Aldrich 361548 GSK-3β Inhibitor VII 99-73-0 5mg $172 2024-03-01 Buy
TCI Chemical A5501 4-Bromophenacyl Bromide [for HPLC Labeling] >99.0%(T) 99-73-0 5g $115 2024-03-01 Buy
TCI Chemical D0164 4-Bromophenacyl Bromide >98.0%(GC) 99-73-0 25g $35 2024-03-01 Buy
Alfa Aesar A13687 2,4'-Dibromoacetophenone, 98+% 99-73-0 25g $62.65 2024-03-01 Buy
Product number Packaging Price Buy
68082 5g $78.3 Buy
361548 5mg $172 Buy
A5501 5g $115 Buy
D0164 25g $35 Buy
A13687 25g $62.65 Buy

2,4'-Dibromoacetophenone Chemical Properties,Uses,Production

Chemical Properties

2,4'-Dibromoacetophenone is off-white crystals or powder

Uses

Identification of carboxylic acids.

Uses

Undergoes condensation reactions with aldehydes in the presence of SnCl21 or SmI32 to afford α,β-unsaturated ketones. Also useful in the esterification of carboxylic acids.3

Uses

2,4'-Dibromoacetophenone is used as a reagent for analysis of fatty acids by HPLC as 4-bromophenacyl esters, for use in the protection of phenols and carboxylic acids. It undergoes condensation reactions with aldehydes in the presence of SnCl2 or SmI3 to afford α,β-unsaturated ketones. It is also useful in the esterification of carboxylic acids.

General Description

A phenyl α-bromomethyl ketone compound that acts as a cell-permeable, and non-ATP competitive inhibitor of GSK-3β (IC50 = 0.5 μM). This reactive alkylating agent is selective towards GSK-3β and does not affect PKA activity even at concentrations as high as 100 μM.

Biochem/physiol Actions

Cell permeable: yes

Purification Methods

Crystallise the bromide from EtOH (ca 8mL/g). [Beilstein 7 IV 652.]

2,4'-Dibromoacetophenone synthesis

13195-79-4
99-73-0
Synthesis of 2,4'-Dibromoacetophenone from ALPHA,ALPHA,4-TRIBROMOACETOPHENONE

2,4'-Dibromoacetophenone Preparation Products And Raw materials

Raw materials

4'-Bromoacetophenone

Preparation Products

2-(4-BROMOBENZOYL)-1-BENZOFURAN-5-CARBALDEHYDE 4-(4-BROMO-PHENYL)-1H-IMIDAZOLE 3-(4-BROMOPHENYL)ISOXAZOL-5-AMINE 2-(4-bromophenyl)morpholine 2-Amino-4'-bromoacetophenone
1-(4-bromophenyl)-2-chloroethan-1-one 2-Thiazolecarboxylic acid,4-(4-bromophenyl)-,ethyl ester 1-(4-Bromophenyl)-2-(4-methylpiperazin-1-yl)ethanone 6-(4-BROMOPHENYL)-3-PHENYL-7H-[1,2,4]TRIAZOLO[3,4-B][1,3,4]THIADIAZINE 4-(4-BROMOPHENYL)-2(3H)-THIAZOLONE HYDRAZONE

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2,4'-Dibromoacetophenone Suppliers

Global( 271)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Mojin Biotechnology Co., Ltd 		+8613288715578 sales@hbmojin.com China 12456 58
Shaanxi Haibo Biotechnology Co., Ltd 		+undefined18602966907 qinhe02@xaltbio.com China 1000 58
Anhui Ruihan Technology Co., Ltd 		+8617756083858 daisy@anhuiruihan.com China 994 58
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Shanghai Daken Advanced Materials Co.,Ltd 		+86-371-66670886 info@dakenam.com China 15928 58
Shanghai Bojing Chemical Co.,Ltd. 		+86-86-02137122233 +8613795318958 bj1@bj-chem.com China 298 55
Shanxi Naipu Import and Export Co.,Ltd 		+86-13734021967 +8613734021967 kaia@neputrading.com China 1011 58
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29914 58
Zhejiang ZETian Fine Chemicals Co. LTD 		18957127338 stella@zetchem.com China 2141 58
SHANDONG ZHI SHANG CHEMICAL CO.LTD 		+86 18953170293 sales@sdzschem.com China 2931 58
Supplier Advantage
Hebei Mojin Biotechnology Co., Ltd 		58
Shaanxi Haibo Biotechnology Co., Ltd 		58
Anhui Ruihan Technology Co., Ltd 		58
Capot Chemical Co.,Ltd. 		60
Shanghai Daken Advanced Materials Co.,Ltd 		58
Shanghai Bojing Chemical Co.,Ltd. 		55
Shanxi Naipu Import and Export Co.,Ltd 		58
career henan chemical co 		58
Zhejiang ZETian Fine Chemicals Co. LTD 		58
SHANDONG ZHI SHANG CHEMICAL CO.LTD 		58

View Lastest Price from 2,4'-Dibromoacetophenone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,4′-dibromoacetophenone 2 pictures 2024-04-15 2,4′-dibromoacetophenone 2
99-73-0
 US $1.00-100.00 / mg 100mg 0.99 5ton/month ANHUI SHENGZHIKAI BIOTECHNOLOGY CO.,LTD
2,4'-Dibromoacetophenone pictures 2024-04-12 2,4'-Dibromoacetophenone
99-73-0
 US $0.00 / kg 1kg 99% 2000ton Shaanxi Haibo Biotechnology Co., Ltd
2,4'-Dibromoacetophenone pictures 2023-08-31 2,4'-Dibromoacetophenone
99-73-0
 US $0.00 / KG 1KG 99% 50000KG/month Hebei Mojin Biotechnology Co., Ltd

2,4'-Dibromoacetophenone Spectrum

2,4'-Dibromoacetophenone(99-73-0)MS2,4'-Dibromoacetophenone(99-73-0)1HNMR2,4'-Dibromoacetophenone(99-73-0)13CNMR2,4'-Dibromoacetophenone(99-73-0)IR12,4'-Dibromoacetophenone(99-73-0)IR22,4'-Dibromoacetophenone(99-73-0)IR3

99-73-0(2,4'-Dibromoacetophenone)Related Search:

3-Nitroacetophenone 4-Bromophenethyl alcohol Bromoacetyl bromide 4-Nitroacetophenone 4-Bromoanisole
L-PICEIN Ethidium bromide Clidinium bromide 4'-Methoxyacetophenone Sodium bromate
Acetophenone 4-Bromobenzotrifluoride 4-Bromotoluene 4-Bromobenzaldehyde 2',4'-Difluoroacetophenone
1,4-Dibromobenzene Acetyl bromide 3-Aminoacetophenone

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OMEGA-BROMOACETOPHENONE bromomethyl4-bromophenylketone bromomethylp-bromophenylketone omega,4-dibromoacetophenone p,alpha-dibromoacetophenone p-Dibromoacetophenone 2,4’-dibromo-acetophenon 2-bromo-1-(4-bromophenyl)-ethanon 4,alpha-dibromoacetophenone 4-bromo(bromoacetyl)benzene -4-Dibromoacetophenone 4-BROMOPHENACYL BROMIDE [FOR HPLC LABELING] 4-BROMOPHENACYL BROMIDE (2,4''-DIBROMOACETOPHENONE) 2,4'-Dibromoacetophenone, 98+% PARA-BROMOPHENACYLBROMIDE Acetophenone, 2,4'-dibromo 2,4'-Dibromoacetophenone GSK-3β Inhibitor VII 2,4′-Dibromoacetophenone,4′-Bromophenacyl bromide 2-Bromo-4'-bromoacetophenone 4-Bromophenacyl Bromide 99% Ar a,4-Dibromoacetophenone 4-BROMOPHENACYL BROMIDE, FOR FLUOR-ESCEN CE BromophenacylBromide 4-BromophenacylBromide98% 4-Bromophenacyl Bromide 98% Ethanone, 2-bromo-1-(4-bromophenyl)- à-4-dibromoacetophenone 2,4'-DibroMo-acetophenone > 2,4- twobroMoacetophenone 2,4'-DibroMoacetophenone, 97+% 2,4'-Dibromoacetophenone puriss., >=98.5% (HPLC) ALPHA,4'-DIBROMOACETOPHENONE ALPHA-4-DIBROMOACETOPHENONE ALPHA,P-DIBROMOACETOPHENONE AKOS BBS-00000865 4'-BROMOPHENACYL BROMIDE 4,OMEGA-DIBROMOACETOPHENONE A,P-DIBROMOACETOPHENONE GSK-3BETA INHIBITOR VII DIBROMOACETOPHENONE-2,4 GSK-3β Inhibitor VII - CAS 99-73-0 - Calbiochem Platinum oxide monohydrate (IV) 4-Bromophenacyl Bromide > 4-Bromophenacyl Bromide [for HPLC Labeling]> 2,4'-DIBROMOACETOPHENONE FOR SYNTHESIS 2,4′-dibromoacetophenone 2 P-BROMOPHENACYL BROMIDE PBPB p-bromophenacyl-8 99-73-0 4-BROMOPHENACYL BROMIDE 2-BROMO-1-(4-BROMOPHENYL)ETHANONE 2-BROMO-1-(4-BROMOPHENYL)ETHAN-1-ONE ω.ρ-Dibromoacetoplenone 2,4'-Dibromoacetophenone 99-73-0 BrCH2COC6H4Br