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Masoprocol

Masoprocol structure

CAS No.: 27686-84-6

Chemical Name:: Masoprocol

Synonyms: CHX-100;masoprocol;NORHYDROGUAIARETICACID;Masoprocol(nordihydroguaiaretic);meso-4，4'-(2，3- Dimethyltetramethylene)dipyrocatechol;(R*,S*)-4,4'-(2,3-dimethylbutane-1,4-diyl)bispyrocatechol;4-[4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]benzene-1,2-diol;4,4'-((2R,3S)-2,3-DiMethylbutane-1,4-diyl)bis(benzene-1,2-diol);4-[(2S,3R)-4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]pyrocatechol;rel-4,4'-((2R,3S)-2,3-Dimethylbutane-1,4-diyl)bis(benzene-1,2-diol)

CBNumber:: CB6855231

Molecular Formula:: C18H22O4

Molecular Weight:: 302.36

MDL Number:: MFCD00866548

MOL File:: 27686-84-6.mol

Last updated:2023-05-25 18:01:16

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Masoprocol Properties

Melting point	185.5°C
Boiling point	526.5±45.0 °C(Predicted)
Density	1.241±0.06 g/cm3(Predicted)
storage temp.	2-8°C
pka	9.56±0.10(Predicted)
LogP	3.710 (est)
EWG's Food Scores	4
NCI Dictionary of Cancer Terms	masoprocol
FDA UNII	7BO8G1BYQU
NCI Drug Dictionary	masoprocol
ATC code	L01XX10
EPA Substance Registry System	1,2-Benzenediol, 4,4'-(2,3-dimethyl-1,4-butanediyl)bis-, (R,S)- (27686-84-6)

Masoprocol price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Biosynth Carbosynth	FB151770	1,2-Benzenediol, 4,4'-(2,3-dimethyl-1,4-butanediyl)bis-, (r,s)-	27686-84-6	2mg	$59	2021-12-16	Buy
Biosynth Carbosynth	FB151770	1,2-Benzenediol, 4,4'-(2,3-dimethyl-1,4-butanediyl)bis-, (r,s)-	27686-84-6	5mg	$118	2021-12-16	Buy
Biosynth Carbosynth	FB151770	1,2-Benzenediol, 4,4'-(2,3-dimethyl-1,4-butanediyl)bis-, (r,s)-	27686-84-6	10mg	$205	2021-12-16	Buy
Biosynth Carbosynth	FB151770	1,2-Benzenediol, 4,4'-(2,3-dimethyl-1,4-butanediyl)bis-, (r,s)-	27686-84-6	25mg	$409	2021-12-16	Buy
American Custom Chemicals Corporation	API0001379	MASOPROCOL 95.00%	27686-84-6	500MG	$434	2021-12-16	Buy

Product number	Packaging	Price	Buy
FB151770	2mg	$59	Buy
FB151770	5mg	$118	Buy
FB151770	10mg	$205	Buy
FB151770	25mg	$409	Buy
API0001379	500MG	$434	Buy

Masoprocol Chemical Properties,Uses,Production

Description

Masoprocol is a lipoxygenase inhibitor launched as a topical agent for the treatment of solar or actinic keratoses. It is the first new topical treatment for pre-malignant skin lesions introduced in twenty years. Masoprocol is obtained from the Larrea tridentata plant and is also under investigation for the treatment of lung, breast, colon and ovarian cancers.

Originator

Chemex (U.S.A.)

Uses

Antineoplastic.

Definition

ChEBI: Masoprocol is the meso-form of nordihydroguaiaretic acid. An antioxidant found in the creosote bush, Larrea divaricata, it is a potent lipoxygenase inhibitor that interferes with arachidonic acid metabolism. It also inhibits (though to a lesser extent) formyltetrahydrofolate synthetase, carboxylesterase, and cyclooxygenase. It has a role as an antineoplastic agent, a lipoxygenase inhibitor, a hypoglycemic agent and a metabolite.

brand name

Actinex (University Of Arizonia Cancer Center).

Masoprocol Preparation Products And Raw materials

Raw materials

Palladium(II) oxide Copper Hydrochloric acid Bromide

Preparation Products

Masoprocol Suppliers

Global( 22)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49739	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131981	58
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	14059	65
NCE Biomedical Co.,Ltd.	4000-027-021 \|24 +86-13986109188 \| +86-15623472865 \| +81-08033611988		China	1494	55
LETOPHARM LIMITED	+86-21-5821 5861	sales@letopharm.com	China	2384	58
Aikon International Limited	025-58859352 18068836627	sales01@aikonchem.com	China	15085	58
Changzhou Bojia Biomedical Technology Co., Ltd.	2122619822	czbjpharma@126.com	China	18488	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24131	58
Shaanxi Dideu Newmaterial Co., Ltd.	029-63373950 15353716720	1052@dideu.com	China	10007	58
Shanghai Tachizaki Biomedical Research Center	18014399201	sales@chemlab-tachizaki.com	China	2488	58

Supplier	Advantage
Hangzhou MolCore BioPharmatech Co.,Ltd.	58
Amadis Chemical Company Limited	58
BOC Sciences	65
NCE Biomedical Co.,Ltd.	55
LETOPHARM LIMITED	58
Aikon International Limited	58
Changzhou Bojia Biomedical Technology Co., Ltd.	58
TargetMol Chemicals Inc.	58
Shaanxi Dideu Newmaterial Co., Ltd.	58
Shanghai Tachizaki Biomedical Research Center	58

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masoprocol 4-[4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]benzene-1,2-diol (R*,S*)-4,4'-(2,3-dimethylbutane-1,4-diyl)bispyrocatechol Masoprocol(nordihydroguaiaretic) NORHYDROGUAIARETICACID CHX-100 meso-4，4'-(2，3- Dimethyltetramethylene)dipyrocatechol 4-[(2S,3R)-4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]benzene-1,2-diol 4-[(2S,3R)-4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol 4-[(2S,3R)-4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]pyrocatechol 4,4'-((2R,3S)-2,3-DiMethylbutane-1,4-diyl)bis(benzene-1,2-diol) rel-4,4'-((2R,3S)-2,3-Dimethylbutane-1,4-diyl)bis(benzene-1,2-diol) 27686-84-6