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Ethoxyacetic acid

CAS No.
627-03-2
Chemical Name:
Ethoxyacetic acid
Synonyms
Ethoxyacetic;2-ethoxyacetate;ethoxy-aceticaci;Ethylglycolicacid;ETHOXYACETIC ACID;Ethoxyethanoicacid;Aceticacid,ethoxy-;2-ethoxyaceticacid;2-Ethoxyacetic acid;ethyloglycolic acid
CBNumber:
CB7493230
Molecular Formula:
C4H8O3
Molecular Weight:
104.1
MDL Number:
MFCD00004310
MOL File:
627-03-2.mol
MSDS File:
SDS
Last updated:2023-08-24 17:20:48

Ethoxyacetic acid Properties

Boiling point 97-100 °C/11 mmHg (lit.)
Density 1.102 g/mL at 25 °C (lit.)
refractive index n20/D 1.419(lit.)
Flash point 208 °F
storage temp. 2-8°C
solubility Chloroform (Slightly), Methanol (Slightly)
form Liquid
pka 3.65(at 18℃)
color Clear colorless to light yellow
Water Solubility soluble
BRN 1743037
Stability Stable. Combustible. Incompatible with strong oxidizing agents.
CAS DataBase Reference 627-03-2(CAS DataBase Reference)
FDA UNII 467VW095BX
NIST Chemistry Reference Acetic acid, ethoxy-(627-03-2)
EPA Substance Registry System Ethoxyacetic acid (627-03-2)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS05
Signal word  Danger
Hazard statements  H314
Precautionary statements  P280-P301+P330+P331-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363
Hazard Codes  C,Xi
Risk Statements  34
Safety Statements  26-36/37/39-45
RIDADR  UN 3265 8/PG 2
WGK Germany  3
RTECS  AH3600000
Hazard Note  Irritant
TSCA  Yes
HazardClass  8
PackingGroup  III
HS Code  29189900
NFPA 704
1
3 0

Ethoxyacetic acid price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 137111 Ethoxyacetic acid 98% 627-03-2 25g $53 2023-06-20 Buy
Sigma-Aldrich 137111 Ethoxyacetic acid 98% 627-03-2 100g $201 2023-01-07 Buy
TCI Chemical E0377 Ethoxyacetic Acid >98.0%(GC)(T) 627-03-2 25g $52 2024-03-01 Buy
TCI Chemical E0377 Ethoxyacetic Acid >98.0%(GC)(T) 627-03-2 100g $123 2024-03-01 Buy
Alfa Aesar B24194 Ethoxyacetic acid, 98% 627-03-2 25g $72.65 2024-03-01 Buy
Product number Packaging Price Buy
137111 25g $53 Buy
137111 100g $201 Buy
E0377 25g $52 Buy
E0377 100g $123 Buy
B24194 25g $72.65 Buy

Ethoxyacetic acid Chemical Properties,Uses,Production

Chemical Properties

liquid

Uses

Ethoxyacetic acid is used to evaluate toxicity in embryonic stem cell test in mice. It finds application as a biomarker of exposure to alkyl-substituted ethylene glycols and other aliphatic ethers. It is used as a precursor to prepare ethoxy-acetic acid ethoxymethyl ester.

Definition

ChEBI: Ethoxyacetic acid is a carboxylic acid.

General Description

Liquid.

Air & Water Reactions

Water soluble.

Reactivity Profile

An ether and organic acid. Carboxylic acids donate hydrogen ions if a base is present to accept them. They react in this way with all bases, both organic (for example, the amines) and inorganic. Their reactions with bases, called "neutralizations", are accompanied by the evolution of substantial amounts of heat. Neutralization between an acid and a base produces water plus a salt. Carboxylic acids with six or fewer carbon atoms are freely or moderately soluble in water; those with more than six carbons are slightly soluble in water. Soluble carboxylic acid dissociate to an extent in water to yield hydrogen ions. The pH of solutions of carboxylic acids is therefore less than 7.0. Many insoluble carboxylic acids react rapidly with aqueous solutions containing a chemical base and dissolve as the neutralization generates a soluble salt. Carboxylic acids in aqueous solution and liquid or molten carboxylic acids can react with active metals to form gaseous hydrogen and a metal salt. Carboxylic acids, like other acids, react with cyanide salts to generate gaseous hydrogen cyanide. Flammable and/or toxic gases and heat are generated by the reaction of carboxylic acids with diazo compounds, dithiocarbamates, isocyanates, mercaptans, nitrides, and sulfides. Carboxylic acids, especially in aqueous solution, also react with sulfites, nitrites, thiosulfates (to give H2S and SO3), dithionites (SO2), to generate flammable and/or toxic gases and heat. Their reaction with carbonates and bicarbonates generates a harmless gas (carbon dioxide) but still heat. Like other organic compounds, carboxylic acids can be oxidized by strong oxidizing agents and reduced by strong reducing agents. These reactions generate heat.

Health Hazard

ACUTE/CHRONIC HAZARDS: Ethoxyacetic acid is corrosive.

Fire Hazard

Ethoxyacetic acid is combustible.

Biochem/physiol Actions

Ethoxyacetic acid induces testicular toxicity in rats in vivo .

Safety Profile

Experimental reproductive effects. When heated to decomposition it emits acrid smoke and irritating fumes.

64-17-5
3926-62-3
627-03-2
Synthesis of Ethoxyacetic acid from Ethanol and Sodium chloroacetate
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View Lastest Price from Ethoxyacetic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Ethoxyacetic acid pictures 2023-08-24 Ethoxyacetic acid
627-03-2
US $0.00 / KG 1KG 99% 50000KG/month Hebei Mojin Biotechnology Co., Ltd
Ethoxyacetic acid pictures 2022-02-22 Ethoxyacetic acid
627-03-2
US $0.00 / KG 1KG 99.4% 100 tons Honest Joy Holdings Limited
Ethoxyacetic acid pictures 2021-04-26 Ethoxyacetic acid
627-03-2
US $1.00 / PCS 1KG 99% 10 mt Hebei Guanlang Biotechnology Co., Ltd.
2-Ethoxyacetic acid 2-ethoxyaceticacid Aceticacid,ethoxy- ethoxy-aceticaci Ethoxyethanoicacid Glycolic ethyl ether Ethoxyacetic acid,98% Ethylglycolicacid Ethoxyacetic acid,O-Ethylglycolic acid Ethoxyacetic acid, 98% 25GR Glycollicacidethylether α-Ethylglycollicacid ETHOXYACETIC ACID GLYCOLIC ACID ETHYL ETHER Ethoxyaceticacid,97% Ethoxyacetic O-ETHYLGLYCOLIC ACID ethyloglycolic acid Ethyloxyacetic acid 2-ethoxyacetate EthoxyaceticAcid> Acetic acid, 2-ethoxy- Ethoxyacetic acid 627-03-2 2-Bromo-1-phenyl-1-hexanone inhibit,Inhibitor,Ethoxyacetic acid,Endogenous Metabolite 627-03-2 CH3CH2OCH2CO2H C2H5OCH2COOH CARBOXYLIC ACID Carboxylic Acids Carbonyl Compounds C1 to C5 Building Blocks Organic Building Blocks Building Blocks C1 to C5 Carbonyl Compounds Carboxylic Acids Chemical Synthesis Organic Building Blocks Acetics acid and esters Organic acids