N-(3-Trifluoromethylphenyl)piperazine

N-(3-Trifluoromethylphenyl)piperazine Basic information
Product Name:N-(3-Trifluoromethylphenyl)piperazine
Synonyms:LABOTEST-BB LT00044462;3-(PIPERAZIN-1-YL)TRIFLUOROMETHYLBENZENE;3-(TRIFLUOROMETHYL)-N-PHENYLPIPERAZINE;AKOS BBS-00003586;1-(ALPHA,ALPHA,ALPHA-TRIFLUORO-M-TOLYL)PIPERAZINE;1-[3-(TRIFLUOROMETHYL)PHENYL]PIPERAZINE;1-(3-TRIFLUOROMETHYL)-PIPERAZINE;RARECHEM AH CK 0203
CAS:15532-75-9
MF:C11H13F3N2
MW:230.23
EINECS:239-574-4
Product Categories:Piperazines;pharmacetical;Piperidines, Piperidones, Piperazines
Mol File:15532-75-9.mol
N-(3-Trifluoromethylphenyl)piperazine Structure
N-(3-Trifluoromethylphenyl)piperazine Chemical Properties
Boiling point 100-102°C 0,1mm
density 1.226 g/mL at 25 °C(lit.)
refractive index n20/D 1.521(lit.)
Fp >230 °F
storage temp. -20°C
pka8.88±0.10(Predicted)
Sensitive Air Sensitive
BRN 614217
CAS DataBase Reference15532-75-9(CAS DataBase Reference)
NIST Chemistry ReferencePiperazine, 1-[3-(trifluoromethyl)phenyl]-(15532-75-9)
Safety Information
Hazard Codes Xi,C
Risk Statements 36/37/38
Safety Statements 26-36
RIDADR 2735
WGK Germany 3
RTECS TM2820000
Hazard Note Corrosive
HazardClass 8
PackingGroup II
HS Code 29335995
MSDS Information
ProviderLanguage
3-(1-Piperazino)benzotrifluoride English
SigmaAldrich English
ALFA English
N-(3-Trifluoromethylphenyl)piperazine Usage And Synthesis
Chemical Propertiesclear colourless to yellow slightly viscous liquid
Uses1-[3-(Trifluoromethyl)phenyl]piperazine is used in preparation of (Piperazinylethyl)cyclohexanamide derivatives and used as treatment or prevention of D3 and/or 5HT-2 receptor diseases.
DefinitionChEBI: A N-arylpiperazine that is piperazine substituted by a 3-(trifluoromethyl)phenyl group at position 1. A serotonergic agonist used as a recreational drug.
Synthesis Reference(s)Tetrahedron Letters, 37, p. 319, 1996 DOI: 10.1016/0040-4039(95)02162-0
Tag:N-(3-Trifluoromethylphenyl)piperazine(15532-75-9) Related Product Information
Lithium trifluoromethanesulfonate Benzotrifluoride Trifluoromethanesulfonic acid Diphenyl ether Dichloromethylphenylsilane Methyltriphenylphosphonium bromide 1-Methylpiperazine (Trifluoromethyl)trimethylsilane 1,2-Dimethylhydrazine Dihydrochloride Piperazine 4-Aminobenzotrifluoride 1-BENZHYDRYLPIPERAZINE PHENYL VALERATE PHENYL RESIN 1-(4-CHLORO-3-TRIFLUOROMETHYLPHENYL)PIPERAZINE 1-(3-Trifluoromethylphenyl)piperazine hydrochloride N-(3-Trifluoromethylphenyl)piperazine 1-(4-TRIFLUOROMETHYLPHENYL)PIPERAZINE