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Clenbuterol hydrochloride

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Clenbuterol hydrochloride Basic information
Selective β2 adrenergic receptor agonist Uses Category toxic Toxicity grading Acute toxicity Flammability and hazard characteristics Storage properties, warehouse Extinguishing media
Product Name:Clenbuterol hydrochloride
Synonyms:NAB 365CL;4-amino-alpha-((tert-butylamino)methyl)-3,5-dichlorobenzylalcoholhydrochlor;4-amino-alpha-((tert-butylamino)methyl)-3,5-dichloro-benzylalcohomonohydr;4-amino-alpha-((tert-butylamino)methyl)-3,5-dichlorobenzylalkohol-hydrochlor;clenbuterolclorhidrato;nab365;planiparthydrochloride;spiropent
CAS:21898-19-1
MF:C12H19Cl3N2O
MW:313.65
EINECS:244-643-7
Product Categories:Active Pharmaceutical Ingredients;Intermediates & Fine Chemicals;Pharmaceuticals;Adrenoceptor;Amines;Aromatics;bulk drug material
Mol File:21898-19-1.mol
Clenbuterol hydrochloride Structure
Clenbuterol hydrochloride Chemical Properties
mp 174-175.5°C
storage temp. 2-8°C
CAS DataBase Reference21898-19-1(CAS DataBase Reference)
Safety Information
Hazard Codes T,F
Risk Statements 25-39/23/24/25-23/24/25-11
Safety Statements 22-36/37/39-45-36/37-16
RIDADR UN 2811 6.1/PG 3
WGK Germany 3
RTECS DN3180000
HazardClass 6.1(b)
PackingGroup III
MSDS Information
ProviderLanguage
SigmaAldrich English
Clenbuterol hydrochloride Usage And Synthesis
Selective β2 adrenergic receptor agonistClenbuterol-hydrochloride exhibits as white crystalline powder. Its chemical name is hydroxymethyl tert-butanol adrenaline or 2-[(tert-butylamino) methyl] -4-amino-3, 5-dichlorobenzene methoxide salt. It is a kind of potent, selectively β2 adrenergic receptor agonists and can be used for relaxing bronchial smooth muscle for the treatment of bronchial asthma, asthmatic bronchitis and bronchitis with emphysema.
The main component of "Shouroujing" is clenbuterol. Because of its certain effects on animals such as promoting the protein synthesis of muscle, promoting lipid decomposition and reducing fat accumulation, it can cause the relative increase of lean meat content of the animal and thus improving livestock quality. Owing to this property, we also referred it as "growth promoters" and "nutrition re-dispersing agent."
In the early 1960s, it was found that it can promote the animal growth; In the 1970s, the United States had introduced it into poultry production and it has become the world's most widely used β- stimulants. However, as the substance has a strong thermal stability and biochemical stability, after animal consumption, it is capable of forming residue in organs and tissues. Upon eating pork containing clenbuterol, people can get poisoning symptoms. Thus, many countries in the world had sooner or later banned the application of β-agonists in animal husbandry. Many countries have developed detection method for monitoring β-agonists residues and clenbuterol of the feed. In 1997, our government had also banned clenbuterol for being used as feed additives.
Precautions: a minority of patients may get adverse reactions such as mild heart palpitations, tremor, and dizziness with the symptoms gradually disappear in general after the medication. Patients of hyperthyroidism, tachycardia or hypertension should be taken with caution.
Preparation: ordinary tablets, aerosols, suppositories, films agent and patches.
The above information is edited by the Chemicalbook of Dai Xiongfeng
The above information is edited by the Chemicalbook of Dai Xiongfeng.
UsesIt can be used for the prevention and treatment of bronchial asthma, chronic bronchitis, emphysema-accompanied bronchial spasms caused by bronchitis.
It is a kind of β2- adrenergic receptor agonists and can be used as bronchodilators.
Category toxicsubstances
Toxicity gradinghighly toxic
Acute toxicityintraperitoneal-mouse TDL0: 2 mg / kg
Flammability and hazard characteristicsflammable with combustion cause its decomposition into toxic chloride and nitrogen oxide gases
Storage properties, warehousecold, ventilated and dry; store it separately from food raw materials
Extinguishing mediaWater, carbon dioxide, dry, sandy soil.
Chemical PropertiesColourless Microcyrstalline Powder
UsageBronchodilatator;Beta adrenergic agonist
UsageSubstituted phenylethanolamine with β2 sympathomimetic activity. Bronchodilator. A β-Agonist which can be used as a growth promoter in farm animals.
Usagedecongestant bronchodilator
UsageAntiasthmatic
UsageSubstituted phenylethanolamine with 2 sympathomimetic activity. Bronchodilator
Clenbuterol hydrochloride Preparation Products And Raw materials
Tag:Clenbuterol hydrochloride(21898-19-1) Related Product Information
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