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Alogliptin benzoate

Alogliptin benzoate Suppliers list
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Products Intro: CAS:850649-62-6
Purity:99% Package:500G;1KG;5KG;25KG
Company Name: Shanghai Orgpharma Chemical Co., Ltd.  Gold
Tel:+86 (21) 22062033
Products Intro:Product Name:ALOGLIPTIN BENZOATE
Purity:99% HPLC Package:1g,5g,10g, 50g,100g, 250g,500g ,1kg , >1kg
Company Name: Beijing Tupsun Technology Co., Ltd.  Gold
Products Intro:CAS:850649-62-6
Company Name: Beijing Zhongshuo Pharmaceutical Technology Development Co., Ltd  Gold
Products Intro:Product Name:Alogliptin Benzoate
Company Name: Jinan Kaypharm Chemical Co.,Ltd.  Gold
Products Intro:Product Name:Alogliptin benzoate
Alogliptin benzoate Basic information
Indications and Usage Mechanisms of Action Adverse reactions
Product Name:Alogliptin benzoate
Synonyms:(R)-2-((6-(3-aMinopiperidin-1-yl)-3-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)Methyl)benzonitrile benzoate;2-[6-[3(R)-AMinopiperidin-1-yl]-3-Methyl-2,4-dioxo-1,2,3,4-tetrahydropyriMidin-1-ylMethyl]benzonitrile benzoate Monobenzoate;Alogliptin benzoate 2-[[6-[(3R)-3-Amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]benzonitrile benzoate;Alogliptin(Alogliptin benzoate;Alogliptin API;(R)-2-((6-(3-Aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benz;ALOGLIPTIN BENZOATE;2-[[6-[(3R)-3-Amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]benzonitrile benzoate
Product Categories:Inhibitors;antidiabetic;Final material;pharmaceutical intermediate
Mol File:850649-62-6.mol
Alogliptin benzoate Structure
Alogliptin benzoate Chemical Properties
Safety Information
MSDS Information
Alogliptin benzoate Usage And Synthesis
Indications and UsageAlogliptin (benzoic acid) is a type-2 diabetes medication, and it is a type of serine protease dipeptidyl peptidase IV (DPP-4) inhibitor developed by the Japanese company Takeda. Alogliptin, used alone or in combination with other blood sugar-lowering medication, is usually well-tolerated in type-2 diabetes patients. This medication has a low risk of hypoglycemia, with Alogliptin treatment groups ≤8.3% and placebo groups ≤10.5%, and shows no difference between young and elderly patients. In addition to effectively lowering blood sugar, this medicine also lowers the risks of hypoglycemia and weight increase, overcoming great obstacles in patient treatment and providing new hope for diabetes treatment.
Mechanisms of ActionAlogliptin selectively inhibits DPP-4 to reduce the inactivation of glucagon-like peptide 1 (GLP-1) and increase the GLP-1 levels in the body, thus lowering blood sugar. Once blood sugar reaches normal levels, it will cease its sugar-lowering effects, thus effectively reducing the risks of hypoglycemia. Additionally, DPP-4 inhibitor also slows gastric emptying, increases the feeling of fullness, and controls appetite, thus helping patients control their weight.
Adverse reactionsCommon side effects of Alogliptin include nasopharyngitis, headaches, and upper respiratory tract infection. Most side effects are light to moderate and are unrelated to dosage.
DefinitionChEBI: A benzoate salt obtained by combining equimolar amounts of alogliptin and benzoic acid. Used for treatment of type 2 diabetes.
Alogliptin benzoate Preparation Products And Raw materials
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