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Rivaroxaban

Rivaroxaban Suppliers list
Company Name: Nanjing Gold Pharmaceutical Technology Co. Ltd.
Tel: 025-84209270 15906146951
Email: wgp@nanjing-pharmaceutical.com
Products Intro: Product Name:Rivaroxaban
CAS:366789-02-8
Purity:99% Package:50KG;25KG;10KG;5KG;1KG
Company Name: Beijing Cooperate Pharmaceutical Co.,Ltd.
Tel: +86-10-60279497 +86(0)15646567669
Email: sales01@cooperate-pharm.com
Products Intro: Product Name:Rivaroxaban
CAS:366789-02-8
Purity:98% Package:100G;1KG;5KG;10KG;25KG;50KG;100KG
Company Name: Shenzhen Sendi Biotechnology Co.Ltd.
Tel: 0755-23311925 18102838259
Email: Abel@chembj.com
Products Intro: Product Name:Rivaroxaban
CAS:366789-02-8
Purity:99% Package:8470/KG
Company Name: Arromax Pharmatech Co., Ltd.  Gold
Tel:0512-62959601 ,15995748448 ;QQ2063939626
Email:meizhang.sales@arromax.com
Products Intro:Product Name:Rivaroxaban
CAS:366789-02-8
Purity:>99.5% Package:10kg 50kg 100kg
Company Name: Beijing Zhongshuo Pharmaceutical Technology Development Co., Ltd  Gold
Tel:010-64430626/13801208576
Email:maggie@chinazhongshuo.com
Products Intro:Product Name:Rivaroxaban
CAS:366789-02-8
Purity:99%
Rivaroxaban Basic information
Indications and Usage
Product Name:Rivaroxaban
Synonyms:5-Chloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-2-thiophenecarboxamide;BAY 59-7939;Rivaroxaban;5-Chloro-N-(((5S)-2-oxo-3-(4-(3-oxomorpholin-4-yl)phenyl)-1,3-oxazolidin-5-yl)methyl)thiophene-2-carboxamide;2-Thiophenecarboxamide, 5-chloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl];Xarelto;(S)-5-chloro-N-((2-oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)thiophene-2-carboxamide;Rivaroxaban (BAY59-7939)
CAS:366789-02-8
MF:C19H18ClN3O5S
MW:435.88
EINECS:
Product Categories:Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;API;Inhibitor;Rivaroxaban;Pharmaceutical raw materials;Inhibitors
Mol File:366789-02-8.mol
Rivaroxaban Structure
Rivaroxaban Chemical Properties
Melting point 228-229°C
storage temp. Refrigerator
Safety Information
MSDS Information
Rivaroxaban Usage And Synthesis
Indications and UsageRivaroxaban is an antithrombotic drug and was developed in a collaboration between the German Bayer Pharmaceuticals and American Johnson company. It is different from the traditional antithrombotic drug heparin in that Rivaroxaban does not need the participation of antithrombin III and can directly antagonize free and bound Xa factors. Heparin requires the effects of antithrombin III, and has no effect on Xa factors in the prothrombin complex. Rivaroxaban is the first oral direct Xa factor inhibitor in the whole world, and it can selectively and competitively inhibit free and bound Da factors as well as prothrombin activity. It uses a dose-dependent method to extend the partial thromboplastin time (PTT) and activated partial thromboplastin time (aPTT) to extend clotting time and lower thrombin genesis. Rivaroxaban has the characteristics of high bioavailability, wide range of target diseases, stable dose-effect relationship, easy oral intake, and low bleeding risk.
Rivaroxaban can also prevent and treat venous thrombosis. It is mainly used clinically to prevent deep venous thrombosis (DVT) and pulmonary embolism (PE) in adult patients following hip and knee replacement surgery. It is also used to prevent patients with nonvalvular atrial fibrillation from cerebral apoplexy and noncentral nervous system embolism, and it can lower the recurrence risk of coronary syndromes.
Chemical PropertiesWhite Solid
Usesanti-coagulant, Factor X inhibitor
UsesA novel antithrombotic agent. A highly potent and selective, direct FXa inhibitor
DefinitionChEBI: A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-chlorothiophene-2-carboxylic acid with the amino group of 4-{4-[(5S)-5-(aminomethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl}morpholin-3-one. An anticoagulant u ed for prophylaxis of venous thromboembolism in patients with knee or hip replacement surgery.
Rivaroxaban Preparation Products And Raw materials
Tag:Rivaroxaban(366789-02-8) Related Product Information
Bortezomib Selumetinib (+)-JQ1 MK-2206 2HCl Apixaban Dabigatran etexilate Dabigatran 4-(4-AMINOPHENYL)MORPHOLIN-3-ONE