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| | Ethyl dimethylphosphonoacetate Basic information |
| Product Name: | Ethyl dimethylphosphonoacetate | | Synonyms: | DIMETHYL(ETHOXYCARBONYLMETHYL)PHOSPHONATE;ETHOXYCARBONYLMETHYLPHOSPHONIC ACID DIMETHYL ESTER;ETHYL DIMETHYLPHOSPHONOACETATE;PHOSPHONOACETIC ACID P,P-DIMETHYL ETHYL ESTER;ethyl (dimethoxyphosphinoyl)acetate;ETHYL DIMETHYLPHOSPHONOACETATE 98%;Ethyl dimethyl phosphonoacetate, 98 %;Ethoxycarbonylmethylphosphonic acid dimethylester, Phosphonoacetic acid P,P-dimethyl ethylester | | CAS: | 311-46-6 | | MF: | C6H13O5P | | MW: | 196.14 | | EINECS: | 206-222-6 | | Product Categories: | | | Mol File: | 311-46-6.mol |  |
| | Ethyl dimethylphosphonoacetate Chemical Properties |
| Boiling point | 134 °C10 mm Hg(lit.) | | density | 1.188 g/mL at 25 °C(lit.) | | refractive index | n20/D 1.435(lit.) | | Fp | 99 °C | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | form | clear liquid | | color | Colorless to Almost colorless | | BRN | 1777603 | | InChI | InChI=1S/C6H13O5P/c1-4-11-6(7)5-12(8,9-2)10-3/h4-5H2,1-3H3 | | InChIKey | HUNISAHOCCASGM-UHFFFAOYSA-N | | SMILES | C(OCC)(=O)CP(OC)(OC)=O |
| Hazard Codes | Xi | | Safety Statements | 23-24/25 | | WGK Germany | 3 | | HS Code | 2920907090 |
| | Ethyl dimethylphosphonoacetate Usage And Synthesis |
| Uses | Reactant for synthesis of:
- Non-nucleoside inhibitors of HCV polymerase NS5B
- Neuropeptide Y1 receptor antagonists
- Alkenylcarboxylates from Horner-Wadsworth-Emmons reactions
Reactant for:
- Enantioselective transfer hydrogenation for preparation of the C7-C14 fragment of ulapualide A
- Intramolecular Michael reactions
- Olefination of peptidyl aldehydes with stabilized ylides
| | Application |
Ethyl dimethylphosphonoacetate could prepare a temporary plugging agent with hydroxyethylpyrrolidone and ethyl perfluorobutyl ether. The temporary plugging agent is useful for oil-water wells.
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| | Ethyl dimethylphosphonoacetate Preparation Products And Raw materials |
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