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Fenbendazole

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CAS:43210-67-9
Purity:98%(Min,HPLC) Package:100g;1kg;5kg,10kg,25kg,50kg
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CAS:43210-67-9
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Products Intro:Product Name:Fenbendazole
CAS:43210-67-9
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Products Intro:Product Name:Fenbendazole
CAS:43210-67-9
Purity:98.0%(LC&N) Package:25G
Fenbendazole Basic information
Benzimidazole anthelmintics Aofendazuo Chemical Properties Uses Production method
Product Name:Fenbendazole
Synonyms:hoe881;Fenbedazole;Fenbendazole CPV2000 EP2000;FENBENDAZOLE VETRANAL;FENBENDAZOLE EP STANDARD;FENBENDAZOLE BP STANDARD;FENBENDAZOLE IMPURITY BMETHYL[5(6)-CHLOROBENZIMIDAZOL-2-YL]CARBAMATE EP STANDARD;FENBENDAZOLE USP STANDARD
CAS:43210-67-9
MF:C15H13N3O2S
MW:299.35
EINECS:256-145-7
Product Categories:PHARMACEUTICALS;Active Pharmaceutical Ingredients;API;Intermediates & Fine Chemicals;Veterinaries;Amines;Aromatics;Heterocycles;Sulfur & Selenium Compounds;ProteasomeInhibitors;PANACUR;Other APIs;vermifuge
Mol File:43210-67-9.mol
Fenbendazole Structure
Fenbendazole Chemical Properties
Melting point 233°C
storage temp. 0-6°C
Merck 14,3960
CAS DataBase Reference43210-67-9(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-24/25
WGK Germany 2
RTECS DD6520500
MSDS Information
Fenbendazole Usage And Synthesis
Benzimidazole anthelminticsFenbendazole is a benzimidazole anthelmintic with a broad spectrum,high efficiency and low toxicity ,in the structure,it has a strong affinity with the parasite tubulin ,by influencing cell transport and energy metabolism,it plays a role in preventing the polymerization of micro tubes, which ultimately destroys the integrity of parasite cells and energy transmission.
Fenbendazole is used to drive and to kill the animal gastrointestinal parasites, it not only has a highly anthelmintic activity on animal gastrointestinal roundworms, hookworms, whipworms, some tapeworms and nematodes , but also has a preferred effect on the part of the bronchial tree and lung parasites (Aelurostrongylus abstrutus and lung fluke) .
AofendazuoAofendazuo is a benzimidazole anthelmintic, also known as the Austrian phenol metronidazole, oxfendazole, benzene etomidate sulfoxide, benzene sulfur oxygen imidazole ,it is the sulfoxide form of Fenbendazole , white or off-white powder at room temperature, slight special smell, it can damage the microtubules of the worms epithelial cells of the gastrointestinal tract, and inhibit the worms uptake of glucose from the intestine.
Aofendazuo is used for the treatment and control of gastrointestinal adults and larvae, it has a good effect on the treatment of in vivo roundworms and lung worms in pigs and sheep , including Oster nematodes (Ostertagia), Haemonchus , Trichostrongylus, Nematodirus , Cooper nematode (Cooperia), capillary nematodes (Capillaria), toothed Oesophagostomum (Oesophagostomum), Chabertia, Trichuris nematodes form (Trichuris) and dictyocaulasis ( Dictyocaulus) and so on.
The above information is edited by the chemicalbook of Tian Ye.
Chemical PropertiesGray light brown crystalline powder. Melting point 233 ℃ (decomposition). Soluble in dimethyl sulfoxide (DMSO), slightly soluble in common organic solvents, insoluble in water. Odorless, tasteless.
UsesAnthelmintic. Broad-spectrum, high efficiency, low toxicity, antiparasitic. It has a strong killing effect on Roundworm, nematodes, tapeworms, cysticercosis , Fasciola and other parasites, not only killing worms, especially having a great effect on Transitional larvae ehich are hazardous to the liver, lungs and intestines .Fenbendazole is a benzimidazole anthelmintic, not only having a highly anthelmintic activity for gastrointestinal nematodes adults and larvae , but also having a good effect on dictyocaulasis, flukes and tapeworms, in addition,it has a strong killing eggs effect.
Production method5-chloro-2-nitroaniline reacts with benzene thiol, to thereby obtain 5-phenylthio-2-nitroaniline in 91% yield.Generate 3-phenylthio-o-phenylenediamine by ferrous sulfate-iron reduction in 90% yield. Finally, cyclize it with the S-methyl-melamine Methyl to obtain fenbendazole.
Chemical PropertiesOff-White Solid
UsesAn anthelmintic (Nematodes)
DefinitionChEBI: A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted at positons 2 and 5 by (methoxycarbonyl)amino and phenylsulfanediyl groups, respectively. A broad-spectrum anthelmintic, it is used, particularly in v terinary medicine, for the treatment of nematodal infections.
Fenbendazole Preparation Products And Raw materials
Preparation ProductsOxfendazole
Raw materialsChloroform-->Acetonitrile-->Iron-->o-Phenylenediamine-->3-Chloroaniline-->Thiophenol-->5-Chloro-2-nitroaniline-->5-PHENYLTHIO-2-NITROANILINE
Tag:Fenbendazole(43210-67-9) Related Product Information
Albendazole Parathion-methyl Imidocarb dipropionate Thiophanate-methyl Methyl acetate Methylparaben FENBENDAZOLE SULFOXIDE Thiabendazole Imidazole Benzimidazole Methimazole benzimidazolone Bensulfuron methyl Imidocarb Alkyl benzimidazole Methyl bromide Methyl acrylate Methyl