1,2,4-Triazole: Overview, Antioxidant Activities and Toxicity
1,2,4-Triazole offers diverse pharmacological benefits, including antioxidant properties, but warrants caution due to toxicity concerns, notably as an eye irritant and reproductive toxin.
Nov 12，2024 API
Mertansine: Origin, Pharmacokinetics and Antitumor Activity
Mertansine, a potent antileukemic ansa macrolide from Maytenus ovatus, disrupts microtubules, offering significant potential for targeted cancer therapy.
Nov 12，2024 Natural Products
2-chloro-6-methyl aniline: uses and synthesis
2-chloro-6-methylaniline is a clear yellow to red-brown liquid. This compound is an important organic synthesis intermediate widely applied to chemical pharmacy, pesticides and organic synthesis.
Nov 12，2024 Organic Chemistry
Perampanel: A Promising AMPA Receptor Antagonist for Epilepsy Treatment
Perampanel is used alone or together with other medicines to treat certain types of epilepsy, such as partial onset seizures and generalized tonic-clonic seizures.
Nov 12，2024 API
Estradiol Valerate: Pharmacodynamic Effects, Pharmacokinetics and Dosage and Administration
Estradiol valerate (EV), sold for use by mouth under the brand name Progynova , is an estrogen medication.
Nov 12，2024 API
Btk Kinase Inhibitor: Pharmacodynamics, Pharmacokinetics and Adverse Events
Btk Kinase Inhibitor, a potent and selective Bruton's tyrosine kinase (BTK) inhibitor, exerts its pharmacodynamics through irreversible covalent binding to BTK Cys-481.
Nov 12，2024 API
Bovine serum albumin: A generalist in Biochemistry
BSA is described as a globular non-glycoprotein with a molecular weight close to 66 430. It is made of 583 amino acid residues and has 17 cystine residues (8 disulphides bridges and 1 free thiol group
Nov 11，2024 Biochemical Engineering
Disodium Phosphate: A Comprehensive Overview
Disodium phosphate is a widely used derivative product of phosphoric acid. Disodium phosphate is used directly in water treatment for corrosion control or blended with polyphosphates for corrosion con
Nov 11，2024 API
Ginkgolide B: Origin, Pharmacokinetics and Neuroprotective Effects
Ginkgolide B from Ginkgo biloba offers neuroprotection by reducing infarct size, enhancing survival, and modulating cellular pathways in ischemic strokes.
Nov 11，2024 Natural Products
3-Butenenitrile: Occurrence, Metabolism and Health Effects
3-Butenenitrile plays a key role in industry and surgery, with potential health impacts. Subtoxic exposure may enhance enzyme activities, offering protective effects.
Nov 11，2024 API