The Biological function of Aviptadil
Aviptadil is a synthetic Vasoactive Intestinal Peptide (VIP) that has been studied in respiratory disease conditions.
Jan 2，2024 Biochemical Engineering
The Pharmacokinetics and uses of Teriparatide acetate
The anabolic drug teriparatide acetate has been introduced as a novel therapeutic agent for osteoporosis.
Jan 2，2024 Biochemical Engineering
Synthesis of Ripretinib
Ripretinib was synthesized by construction of a 1,6-naphtholide involving the junction of an α-aryl ester and appropriately functionalized 4-aminopyridine.
Jan 2，2024 Inhibitors
Pralsetinib: Synthesis and Introduction
Pralsetinib (BLU-667) is synthesised using bromopyridine as a raw material by chemical reaction.
Jan 2，2024 Inhibitors
How is Pemigatinib Synthesised?
Pemigatinib is synthesised using pyrrolopyridine as a raw material, firstly by synthesis of Pemigatinib Morpholine Intermediate and then by reduction, cyclisation and other reactions.
Jan 2，2024 Inhibitors
How is Lurbinectedin synthesised?
Lurbinectedin is synthesised using tyrosine derivative as the raw material, firstly the intermediate Lurbinectedin Bridged Azocane is synthesised, and then through esterification and cyclisation.
Jan 2，2024 Drugs
Synthesis of Ensartinib Dihydrochloride
Ensartinib Dihydrochloride is synthesised by a three-step reaction using piperazine as a raw material and the addition of the intermediate compounds Ensartinib Amino Pyridazine and Ensartinib Carboxyl
Jan 2，2024 Inhibitors
Sitagliptin: Pharmacological Profile and Therapeutic Efficacy in Type 2 Diabetes
Sitagliptin, a DPP-4 inhibitor, effectively improves glycaemic control in T2D. Rapid absorption, renal elimination, and proven efficacy as monotherapy therapy demonstrate its clinical benefits.
Jan 2，2024 API
Urolithin A: A Natural Gut Microbiome-Derived Metabolite
Urolithin A, derived from foods like pomegranates, shows potential in promoting health, mitigating diseases, and enhancing longevity.
Jan 2，2024 Natural Products
Allopurinol: the treatment of elevated uric acid levels
Allopurinol, a key gout treatment, inhibits uric acid, explored for cardiovascular benefits, with optimized safety in synthesis.
Jan 2，2024 Drugs