A first-in-class potent 5-HT2A antagonist: Lumateperone
Lumateperone, also known as ITI-007, is a first-in-class potent 5-HT2A antagonist, postsynaptic D2 antagonist, and inhibitor of serotonin transport developed by Intra-Cellular Therapies under a licens
Jan 8，2024 API
The synthesis method of Lemborexant
Lemborexant is an orally administered dual orexin receptor (OXR) antagonist developed by Eisai for the treatment of adults with insomnia.
Jan 8，2024 API
How Lasmiditan works in treating migraine
Lasmiditan, or COL-144, is an orally bioavailable selective serotonin receptor agonist (SSRA) discovered by Eli Lilly and Company and licensed to CoLucid Pharmaceuticals before Eli Lilly acquired CoLu
Jan 8，2024 API
The introduction of Cenobamate (SQ 109)
Cenobamate is the latest approved antiepileptic drug in focal epilepsy, and its mode of action is thought to be mediated by blocking voltage-gated sodium channels and interacting with the GABAergic sy
Jan 8，2024 Biochemical Engineering
Candesartan cilexetil in cardiovascular disease
Candesartan cilexetil is an oral angiotensin II receptor blocker. Candesartan is approved by the FDA for the treatment of hypertension in adults.
Jan 8，2024 Drugs
How to synthesize Brexanolone？
Developed by Sage Therapeutics, brexanolone was approved by the USFDA as a first-in-class treatment for PPD in adult women.
Jan 8，2024 API
What are the side effects of Valsartan?
ommon side effects of Valsartan include: shortness of breath, cough , dizziness and light-headedness on waking, nausea, fatigue, diarrhoea, skin irritation , postural hypotension, hyperkalaemia, and r
Jan 8，2024 Drugs
What is D-Xylose Absorption Test？
This test is done to help diagnose problems that prevent the small intestine from absorbing nutrients in food and evaluate the person’s ability to absorb carbohydrates in general.
Jan 8，2024 Biochemical Engineering
D-Biotin: Application; Side effects and Benefits
D-Biotin is a water-soluble enzyme cofactor that is present in trace amounts in every living cell. It binds primarily to proteins or peptides and is abundant in liver, kidney, pancreas, yeast and milk
Jan 8，2024 Vitamins and Minerals medicines
The role of Lithium bis(oxalate) borate as electrolyte additives
Lithium bis(oxalate) borate is one of the most widely used electrolyte additives in Li-ion batteries and has the potential to be an alternative for the commercially used lithium hexafluorophosphate (L
Jan 8，2024 Inorganic chemistry