Selpercatinib: Synthesis and Description
Selpercatinib (LOXO-292) is synthesised using sulfonyl chloride as a raw material by chemical reaction.
Jan 5，2024 Inhibitors
A brief introduction to triclabendazole
Triclabendazole, also known as CGA 89317 or CGP 23030, is an orally bioavailable anthelmintic against infections caused by Fasciola species.
Jan 5，2024 API
How is Sacituzumab Govitecan Synthesised?
The overall synthetic strategy for the preparation of sacituzumab govitecan inherently consists of three separate sequential components, construction of the payload (SN-38) followed by appendage with
Jan 5，2024 Drugs
β-Carotene: Dietary Sources and Benefits
β-Carotene is found in richer sources, mostly in brightly coloured fruits and vegetables such as carrots, spinach, kale, tomatoes, sweet potatoes, broccoli, onions, peppers, cantaloupe and apricots.
Jan 5，2024 Vitamins and Minerals medicines
How to synthesize Relebactam?
Relebactam, formerly MK-7655, is a DBO that promises to contribute to the renaissance in antimicrobial chemotherapy.
Jan 5，2024 API
The Synthesis method and Pharmacokinetics of Pretomanid (PA 824)
Pretomanid (also known as PA 824) is a nitroimidazooxazine antimycobacterial drug with a complex mechanism of action.
Jan 5，2024 API
A semisynthetic pleuromutilin antibiotic: Lefamulin
Lefamulin, a semisynthetic pleuromutilin antibiotic, has been approved by the FDA for IV and oral treatment of community-acquired bacterial pneumonia (CABP) in adults.
Jan 5，2024 APIThe discussion on the polarity of phenol
The sharing of electrons between O and H is unequal, with the electrons more strongly drawn towards O. This results in an overall polar molecule.
Jan 5，2024 Organic Chemistry
Empagliflozin protects the heart against ischemia/reperfusion-induced sudden cardiac death
Empagliflozin is a selective sodium-glucose cotransporter 2 (SGLT2) inhibitor used to lower blood sugar in adults with type 2 diabetes. Empagliflozin also exerts cardioprotective effects independent f
Jan 5，2024 Drugs
A alternative to fossil fuels: 2,5-Furandicarboxylic acid
2,5-Furandicarboxylic acid can replace petroleum-based terephthalic acid to produce biobased plastic polyethylene furan dicarboxylate (PEF) due to the similarity in its functional group with terephtha
Jan 5，2024 Organic Chemistry