Reactions of hexafluorobenzene under different temperature

The principal mode of aromatic substitution in hexafluorobenzene is by attack of a nucleophilic reagent. Here will introduce reactions of hexafluorobenzene.

Jun 23,2025  Organic Synthesis Intermediate

Diltiazem Hydrochloride: Cardiovascular Applications and Liver Safety Profile

Diltiazem hydrochloride treats angina and arrhythmias by relaxing blood vessels, and shows effective rate control in atrial fibrillation.

Jun 23,2025  API

Baricitinib phosphate salt:Uses,Mechanism of action and Crystal forms

Baricitinib phosphate salt is a JAK kinase inhibitor that inhibits the JAK-STAT signaling pathway in cells in vivo.

Jun 23,2025  API

1-Tetralone Derivatives: Anti-Inflammatory, MAO Inhibition, and Asymmetric Synthesis

1-Tetralone derivatives show anti-inflammatory activity via ROS inhibition, and are synthesized asymmetrically with remote quaternary stereocenters.

Jun 23,2025  Chemical Reagents

Ibrexafungerp: Mechanism of Action and Instructions for Use

Ibrexafungerp is the first fourth-generation antifungal drug with a new mechanism of action. It can cover most Candida, Aspergillus, Penicillium multivariate and rare diphasic fungi (such as Histoplas

Jun 20,2025  API

Tropicamide:Class,Uses,Side effects and Administration

Tropicamide is an alkaloid atropine‐derived anticholinergic drug and a non‐selective antagonist of muscarinic acetylcholine (mACh) receptors.

Jun 20,2025  API

Synthesis, Applications, and Toxicological Implications of 9,9-Bis(4-hydroxyphenyl)fluorene

9,9-Bis(4-hydroxyphenyl)fluorene is used in high-performance polymer synthesis but raises concerns as a bisphenol A (BPA) substitute.

Jun 20,2025  Chemical Reagents

LCZ696: A Dual-Action Inhibitor for Hypertension and Heart Failure

LCZ696, an ARNI combining valsartan and AHU377, reduces blood pressure and improves heart function in hypertension and heart failure.

Jun 20,2025  API

Imatinib: Targeted Tyrosine Kinase Inhibitor Transforming Cancer Treatment

Imatinib revolutionizes CML treatment by blocking leukemic cell proliferation, showing durable responses and long-term survival benefits.

Jun 20,2025  API

Deferiprone: Mechanism of action and Preparation method

Deferiprone is used to treat thalassemia that has not responded well to previous chelation therapy and has excessive iron load due to blood transfusion.

Jun 19,2025  Pesticide Intermediates
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