Dihydrocoumarin: An HDAC Inhibitor with Implications for DNA Repair, Aging, and One - Pot Synthesis
Dihydrocoumarin is a compound in Melilotus officinalis and a flavoring agent that inhibits the NAD-dependent histone deacetylase Sir2 in yeast.
Apr 17，2025 API
Novel Synthetic Strategies for Ethyl 6,8 - Dichlorooctanoate
Ethyl 6,8-dichlorooctanoate is a vital intermediate for preparing lipoic acid from adipic acid and with lipoic acid having strong antioxidant capacity.
Apr 17，2025 Chemical Materials
Trimagnesium dicitrate: Pharmacodynamics, Mechanism and Function,etc
Trimagnesium dicitrate is a laxative used in bowel preparation for colonoscopy or as a magnesium supplement.
Apr 17，2025 Drugs
Dehydroepiandrosterone acetate: a natural hormone
Dehydroepiandrosterone acetate (DHEA)is involved in various physiological functions and has been studied in diseases and clinical applications.
Apr 17，2025 API
In-Depth Exploration of 3-Bromoanisole and Its Deuterated Analogue
3-Bromoanisole, a useful brominating agent from HOBr and anisole reaction, is synthesized from 3/4 - bromophenol (87% yield).
Apr 16，2025 Chemical Reagents
Advances in Synthetic Methodologies of 2-chloro-5-cyanopyridine
2-chloro-5-cyanopyridine is a crucial compound in pharmaceutical and agrochemical synthesis due to its reactivity and versatility.
Apr 16，2025 Chemical Materials
Unraveling the Catalytic Potential of L - Prolinamide in Aldol and Related Reactions
L-Prolinamide, as a component of thyrotropin-releasing hormone, has significant functions in the endocrine system like promoting of TSH and prolactin.
Apr 16，2025 Catalyst and Auxiliary
Mesosulfuron - Methyl: Unraveling Resistance Mechanisms in Weeds and Its Impact on Soil Ecology
Mesosulfuron-methyl is applied in experiments as a systemic herbicide for cereals inhibiting plant amino acid synthesis.
Apr 16，2025 Organic Chemistry
Pemetrexed Disodium: From Clinical Trials to Purity Control and Synthesis
Pemetrexed disodium is a new multitargeted antifolate and the first chemotherapy agent approved in combination with cisplatin.
Apr 16，2025 API
Eltrombopag: Synthesis and Mechanism
Eltrombopag is a thrombopoietin receptor agonist used to treat thrombocytopenia or aplastic anemia associated with various etiologies.
Apr 16，2025 Drugs