D-Pyroglutamic Acid: A Cause of High Anion Gap Acidosis and Its Clinical Implications
D-Pyroglutamic acid can cause high anion gap acidosis, related to glutathione depletion, and requires consideration in both pediatric and adult patients.
May 28，2025 Chemical Materials
Ethyl 3,4-dihydroxybenzoate: Antibiotic Potentiating and Hypoxia-Attenuating Properties
Ethyl 3,4-dihydroxybenzoate can potentiate antibiotics against drug-resistant E. coli and attenuate hypoxia-induced cerebral injury in rats.
May 28，2025 Antioxidants
Two methods for determination of 1-methylpyrrolidine
1-Methylpyrrolidine is an organic base and inactive to UV absorption. The following are two research reports on the detection method of 1-methylpyrrolidine.
May 26，2025 Pharmaceutical intermediates
Biapenem: Efficacy, Safety and Pharmacokinetics Compared with Meropenem and in Elderly Subjects
Biapenem is a carbapenem antibiotic in which the azetidine and pyrroline rings carry 1-hydroxymethyl and pyrazolo[1,2-a][1,2,4]triazolium-6-ylthio substituents.
May 26，2025 API
Olaparib: Efficacy in Advanced Cancers and Role in Ovarian Cancer Maintenance Therapy
Olaparib is a prescription medicine that targets cancer cells with abnormal BRCA or HRR genes which is used as maintenance or adjuvant therapy.
May 23，2025 API
Cinchonine: Multifaceted Roles in Cancer Treatment and as a GLP - 1R Agonist
Cinchonine is a cinchona alkaloid generally found in the bark of Cinchona officinalis plants and a pseudoenantiomer employed in malaria therapy.
May 23，2025 API
Eleutheroside B: A Promising Compound with Cardiac and Neuroprotective Effects
Eleutheroside B (EB) is the main active constituent derivedthat has been reported to possess cardioprotective effects.
May 22，2025 API
The isotopes of yttrium in Medical Applications and Radioembolization
Yttrium is rare earth mineral found in uranium ores. It is not present in free form. It is considered as the 28th most abundant element in the earth’s crust.
May 22，2025 Chemical Materials
Terbutaline Sulfate: Applications, Pharmacokinetics and Effects
Terbutaline Sulfate, a synthetic beta-2 agonist since the late 1960s, is used for bronchospasm in respiratory diseases and has off-label uses.
May 21，2025 API
Pancuronium bromide: Pharmacology, ADME properties and Side-effects
Pancuronium bromide is a nondepolarizing muscle relaxant used to relax muscles or as an anesthesia to stop pain during surgeries.
May 21，2025 Drugs