| Identification | More | [Name]
Potassium thioacetate | [CAS]
10387-40-3 | [Synonyms]
Ethanethioic acid potassium salt
KTAA
MERCAPTOACETIC ACID, POTASSIUM SALT
POTASSIUM THIOACETATE
POTASSIUM THIOACETIC ACID
POTASSIUM THIOLACETATE
S-POTASSIUM THIOACETATE
THIOACETIC ACID POTASSIUM
THIOACETIC ACID POTASSIUM SALT
THIOACETIC ACID S-POTASSIUM SALT
thiolacetic acid potassium salt
TIOACETIC ACID POTASSIUM SALT
Potassium thioacetate/Thioacetic acid potassium salt
Potassium Thioacetic
Potassium thioacete
Potassium ethanethioate
Ethanethioic acid potassium salt, Thioacetic acid potassium salt, Thiolacetic acid potassium salt
Acetic acid, thio-, potassium salt
Potassium thioethanoate | [EINECS(EC#)]
233-848-7 | [Molecular Formula]
C2H3KOS | [MDL Number]
MFCD00083065 | [Molecular Weight]
114.21 | [MOL File]
10387-40-3.mol |
| Chemical Properties | Back Directory | [Appearance]
white to light brown crystalline powder, crystals | [Melting point ]
173-176 °C (lit.) | [bulk density]
500kg/m3 | [density ]
1.58 g/cm3 | [storage temp. ]
Refrigerator (+4°C) | [solubility ]
soluble | [form ]
Crystalline Powder, Crystals or Chunks | [pka]
3.6 | [color ]
White to light brown | [Water Solubility ]
soluble | [Hydrolytic Sensitivity]
4: no reaction with water under neutral conditions | [Sensitive ]
Air Sensitive & Hygroscopic | [BRN ]
3595448 | [InChI]
InChI=1S/C2H4OS.K/c1-2(3)4;/h1H3,(H,3,4);/q;+1/p-1 | [InChIKey]
AFNBMGLGYSGFEZ-UHFFFAOYSA-M | [SMILES]
C([S-])(=O)C.[K+] | [CAS DataBase Reference]
10387-40-3(CAS DataBase Reference) | [EPA Substance Registry System]
10387-40-3(EPA Substance) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H315-H319-H335 | [Precautionary statements ]
P261-P280a-P304+P340-P305+P351+P338-P405-P501a | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S37/39:Wear suitable gloves and eye/face protection . | [RIDADR ]
UN 3335 | [WGK Germany ]
3
| [F ]
3-9-13-23 | [TSCA ]
Yes | [REACH Registrations]
Active | [HazardClass ]
9 | [HS Code ]
29309070 | [Storage Class]
11 - Combustible Solids |
| Questions And Answer(Q&A) | Back Directory | [Application]
Potassium thioacetate is an organosulfur compound and a salt with the formula CH3COS−K+. This white, water-soluble solid is used as a reagent for preparing thioacetate esters and other derivatives . It acts as a sulfur source in the synthesis of sulfur-containing organic compounds for the synthesis of heterocycles, polymers, transition-metal ligands, nanoparticles, bioactive compounds and macromolecular inclusion complexes. It is also used for palladium mediated coupling with aryl halides and triflates leading to S-arylthioacetates and derivatives and it is also used as a reagent in the conversion of halides to thiols.
|
| Hazard Information | Back Directory | [Chemical Properties]
white to light brown crystalline powder, crystals | [Uses]
Potassium Thioacetate is the potassium salt of Thioacetic Acid, a commonly used reagent in organic synthesis for the introduction of thiol groups in molecules. | [Reactions]
Thioacetate is also a class of sulfur-containing nucleophiles, of which potassium thioacetate is the most widely used reagent. Potassium thioacetate reacts with organic halides to form thioesters, which are often used as thiol-protecting groups.In the classical reaction, potassium thioacetate replaces the bromine atom to form a thiol in which the thioester formed in the first step is subjected to a nucleophilic addition elimination reaction to obtain a thiol via hydrolysis, alcoholysis or ammonolysis. Unlike the thiol formation from bromine and thiourea, this method is not strictly limited to polystyrenes. It can also be extended to poly(meth)acrylate systems. It is important that there is no observation of ester hydrolysis during the process. |
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J & K SCIENTIFIC LTD.
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Alfa Aesar
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Energy Chemical
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Jia Xing Isenchem Co.,Ltd
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