| Identification | More | [Name]
2-Amino-4-(trifluoromethyl)pyridine | [CAS]
106447-97-6 | [Synonyms]
2-AMINO-4-(TRIFLUOROMETHYL)PYRIDINE
4-(TRIFLUOROMETHYL)PYRIDIN-2-AMINE
4-Trifluoromethyl-2-pyridinamine
4-Trifluoromethyl-pyridin-2-ylamine | [EINECS(EC#)]
634-596-4 | [Molecular Formula]
C6H5F3N2 | [MDL Number]
MFCD00077455 | [Molecular Weight]
162.11 | [MOL File]
106447-97-6.mol |
| Chemical Properties | Back Directory | [Melting point ]
70-74 °C
| [Boiling point ]
221.3±40.0 °C(Predicted) | [density ]
1.368±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [form ]
Powder, Solid or Crystalline | [pka]
4.55±0.11(Predicted) | [color ]
White to pale brown | [BRN ]
7869677 | [InChI]
InChI=1S/C6H5F3N2/c7-6(8,9)4-1-2-11-5(10)3-4/h1-3H,(H2,10,11) | [InChIKey]
RWGBXAQMUBGGKQ-UHFFFAOYSA-N | [SMILES]
C1(N)=NC=CC(C(F)(F)F)=C1 | [CAS DataBase Reference]
106447-97-6(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
T,Xi,C | [Risk Statements ]
R25:Toxic if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin .
R43:May cause sensitization by skin contact.
R34:Causes burns.
R22:Harmful if swallowed. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37:Wear suitable protective clothing and gloves .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [RIDADR ]
UN 2811 6.1/PG 3
| [WGK Germany ]
3
| [Hazard Note ]
Toxic | [HazardClass ]
6.1 | [HazardClass ]
IRRITANT | [PackingGroup ]
II | [HS Code ]
29333990 |
| Hazard Information | Back Directory | [Uses]
2-Amino-4-trifluoromethylpyridine is a 2-amino-substituted nitrogen-containing six-membered heterocyclic compound, which is used as an important pharmaceutical intermediate. | [Synthesis]
2-Amino-4-(trifluoromethyl)pyridine can be synthesized by chemical reaction of 2-fluoro-4-trifluoromethyl-pyridine, acetamidine hydrochloride, NaOH, H2O and dimethyl sulfoxide under certain conditions. | [References]
[1] Patent: US2010/234607, 2010, A1. Location in patent: Page/Page column 4 |
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