ChemicalBook--->CAS DataBase List--->109806-71-5

109806-71-5

109806-71-5 Structure

109806-71-5 Structure
IdentificationMore
[Name]

4-[(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINEETHANOL DIHYDROCHLORIDE
[CAS]

109806-71-5
[Synonyms]

Cetirizine -EP-Imp-G
Levocetirizine Impurity G
Levocetirizine Impurity 6
(R)-2-(4-((4-chlorophenyl)
2-[4-{Chlorophenyl}Phenylmethyl]-1-
Cetirizine EP Impurity G Hydrochloride
4-(p-Chloro-α-phenylbenzyl)-1-piperazineethanol
1-Piperazineethanol, 4-[(4- chlorophenyl)phenylMethyl]-
2-[4-{4-Chlorophenyl} Phenylmethyl]-1-Piperazinylethanol
2-{4-[(4-CHLORO-PHENYL)-PHENYL-METHYL]-PIPERAZIN-1-YL}-ETHANOL
Cetirizine Impurity 15 Monomer (Cetirizine EP Impurity G Monomer )
4-[(4-Chlorophenyl)phenylMethyl]-(4-hydroxy-1-piperidinyl)-1-butanone
[Molecular Formula]

C19H25Cl3N2O
[MDL Number]

MFCD00035326
[Molecular Weight]

403.77
[MOL File]

109806-71-5.mol
Chemical PropertiesBack Directory
[Boiling point ]

205-208 °C(Press: 0.1 Torr)
[density ]

1.191±0.06 g/cm3(Predicted)
[storage temp. ]

Hygroscopic, -20°C Freezer, Under inert atmosphere
[solubility ]

Ethyl Acetate (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

14.96±0.10(Predicted)
[color ]

White to Off-White
[Stability:]

Very Hygroscopic
[InChI]

InChI=1S/C19H23ClN2O/c20-18-8-6-17(7-9-18)19(16-4-2-1-3-5-16)22-12-10-21(11-13-22)14-15-23/h1-9,19,23H,10-15H2
[InChIKey]

ZJQSBXXYLQGZBR-UHFFFAOYSA-N
[SMILES]

N1(CCO)CCN(C(C2=CC=C(Cl)C=C2)C2=CC=CC=C2)CC1
[CAS DataBase Reference]

109806-71-5(CAS DataBase Reference)
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Tetrahydrofuran-->Dichloromethane-->Thionyl chloride-->Toluene-->Triethylamine-->Benzene-->1,4-Dioxane-->Sodium borohydride-->Isopropyl alcohol-->Piperazine-->Calcium chloride-->2-Bromoethanol-->4-Chlorobenzophenone-->1-(4-Chlorobenzhydryl)piperazine
[Preparation Products]

1-Piperazineacetaldehyde-->Cetirizine
Hazard InformationBack Directory
[Chemical Properties]

Off-White Solid
[Uses]

2-[4-[(4-Chlorophenyl)phenylmethyl]-1-piperazinyl]ethanol is an impurity of (R)-Cetirizine (C281106).
[Uses]

4-(p-Chloro-α-phenylbenzyl)-1-piperazineethanol is used in the synthesis of antifungal triazole and imidazole derivatives. Impurity of an intermediate in the formation of Cetrizine.
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