ChemicalBook--->CAS DataBase List--->111373-03-6

111373-03-6

111373-03-6 Structure

111373-03-6 Structure
IdentificationMore
[Name]

1-(2-CYANOPHENYL)PIPERAZINE
[CAS]

111373-03-6
[Synonyms]

1-(2-CYANOPHENYL)PIPERAZINE
1-(2-CYANPHENYL)-PIPERAZINE
RARECHEM AH CK 0076
2-(1-Piperazino)benzonitrile
Cyanophenylpiperazine
2-piperazin-1-ylbenzonitrile
Benzonitrile, 2-(1-piperazinyl)-(9CI)
1-(2-Cyanophenyl)piperazine 97%
1-(2-CYANOPHENYL)-PIPERAZINE >98%
[Molecular Formula]

C11H13N3
[MDL Number]

MFCD00040793
[Molecular Weight]

187.24
[MOL File]

111373-03-6.mol
Chemical PropertiesBack Directory
[Melting point ]

113-115
[Boiling point ]

314-315 °C (lit.)
[density ]

1.115 g/mL
[refractive index ]

n20/D 1.5890(lit.)
[Fp ]

118 °F
[pka]

8.77±0.10(Predicted)
[Specific Gravity]

1.115
[Sensitive ]

Moisture Sensitive
[BRN ]

785973
[CAS DataBase Reference]

111373-03-6(CAS DataBase Reference)
[Storage Precautions]

Store under inert gas;Air sensitive
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

R10:Flammable.
R36:Irritating to the eyes.
[Safety Statements ]

S16:Keep away from sources of ignition-No smoking .
S24/25:Avoid contact with skin and eyes .
S36:Wear suitable protective clothing .
[RIDADR ]

UN 1993 3/PG 3
[WGK Germany ]

3
[Hazard Note ]

Irritant
[HazardClass ]

8
[PackingGroup ]

II
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Ethyl acetate-->Diethyl ether-->Dichloromethane-->Toluene-->Potassium carbonate-->Dimethyl sulfoxide-->Di-tert-butyl dicarbonate-->Piperazine-->2-Bromobenzonitrile-->2-Fluorobenzonitrile-->2-methylpentane-->1-(2-iodophenyl)piperazine-->1-(2-BROMOPHENYL)PIPERAZINE-->TERT-BUTYL 4-(2-CYANOPHENYL)PIPERAZINE-1-CARBOXYLATE-->Nornitrogen mustard-->Bis(2-chloroethyl)amine hydrochloride-->2-Aminobenzonitrile
Hazard InformationBack Directory
[Uses]

1-(2-cyanophenyl)piperazine is used in the synthesis of melanocortin subtype-4 receptor (MC4R) agonists. MC4R is located in the hypothalamus and helps to regulate metabolism, feeding and reproductive behavior. Agonists to these receptors have shown to decrease feeding behaviors.
Spectrum DetailBack Directory
[Spectrum Detail]

1-(2-CYANOPHENYL)PIPERAZINE(111373-03-6)IR
Well-known Reagent Company Product InformationBack Directory
[Alfa Aesar]

1-(2-Cyanophenyl)piperazine, 97%(111373-03-6)
[Sigma Aldrich]

111373-03-6(sigmaaldrich)
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