| Identification | Back Directory | [Name]
Azido-PEG8-NHS ester | [CAS]
1204834-00-3 | [Synonyms]
N3-PEG8-NHS
N3-PEG8-SPA
1204834-00-3
AZIDO-PEG8-NHS
N3-PEG8-CH2CH2COONHS
Azido-PEG8-NHS ester
Azido-dPEG??-NHS ester
Azido-dPEG(R)8-NHS ester
N3-PEG8-CH2CH2COONHS Ester
N3-PEG8-NHS Ester,Azido-PEG8-NHS ester
2,5-dioxopyrrolidin-1-yl 1-azido-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oate | [Molecular Formula]
C23H40N4O12 | [MDL Number]
MFCD13184949 | [MOL File]
1204834-00-3.mol | [Molecular Weight]
564.583 |
| Chemical Properties | Back Directory | [storage temp. ]
-20°C | [solubility ]
Soluble in DMSO, DCM, DMF | [form ]
solid or viscous liquid | [color ]
Colorless to light yellow | [InChIKey]
AZXJVYAMFTUKFC-UHFFFAOYSA-N | [SMILES]
O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-] |
| Hazard Information | Back Directory | [Description]
Azido-PEG8-NHS ester is a popular click chemistry reagent with an azide and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. | [Uses]
Azido-PEG8-NHS ester series of products contain an azide function on one end of a single molecular weight dPEG? spacer and a reactive group on the other end of the spacer. The dPEG? spacer is hydrophilic and non-immunogenic and improves the water solubility of the target molecule while reducing the immunogenicity and increasing the hydrodynamic volume of the target. | [reaction suitability]
reaction type: click chemistry
reagent type: cross-linking reagent
reaction type: click chemistry | [IC 50]
PEGs; Alkyl/ether; Cleavable Linker |
|
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T&W GROUP
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Sigma-Aldrich
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Borenpharm Co., Ltd
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