| Identification | More | [Name]
Amidosulfuron | [CAS]
120923-37-7 | [Synonyms]
AMIDOSULFURON
GRATIL
n-(((((4,6-dimethoxy-2-pyrimidinyl)amino)carbonyl)amino)sulfonyl)-n-methylmethanesulfonamide
Amidosulfuron PESTANAL
METHYLMETHANESULFONAMIDE
1-(4,6-Dimethoxypyrimidin-2-yl)-3-(N-mesyl-N-methylsulfamoyl)urea | [EINECS(EC#)]
407-380-0 | [Molecular Formula]
C9H15N5O7S2 | [MDL Number]
MFCD01310639 | [Molecular Weight]
369.37 | [MOL File]
120923-37-7.mol |
| Questions And Answer | Back Directory | [Description]
Amidosulfuron is a broad spectrum herbicide that is used to control broad-leaved weeds. It is volatile, highly soluble in water and, based on its chemical properties, has a high potential for leaching to groundwater. It is not persistent in soil systems but may be persistent in water under certain conditions. | [Toxicity]
Amidosulfuron has a low mammalian toxicity and would not be expected to bioaccumulate. Amidosulfuron is moderately toxic to most terrestrial and aquatic species. |
| Chemical Properties | Back Directory | [Melting point ]
160-163°C | [density ]
1.594±0.06 g/cm3(Predicted) | [storage temp. ]
under inert gas (nitrogen or Argon) at 2-8°C | [solubility ]
DMSO (Slightly), Methanol (Slightly, Heated) | [form ]
neat | [pka]
0.12±0.40(Predicted) | [color ]
White to Off-White | [Henry's Law Constant]
6.4×105 mol/(m3Pa) at 25℃, Maniere et al. (2011) | [Stability:]
Hygroscopic, Unstable in Solution | [Major Application]
agriculture
environmental | [InChI]
1S/C9H15N5O7S2/c1-14(22(4,16)17)23(18,19)13-9(15)12-8-10-6(20-2)5-7(11-8)21-3/h5H,1-4H3,(H2,10,11,12,13,15) | [InChIKey]
CTTHWASMBLQOFR-UHFFFAOYSA-N | [SMILES]
COc1cc(OC)nc(NC(=O)NS(=O)(=O)N(C)S(C)(=O)=O)n1 | [LogP]
1.630 | [CAS DataBase Reference]
120923-37-7(CAS DataBase Reference) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS09 | [Signal word ]
Warning | [Hazard statements ]
H410 | [Precautionary statements ]
P273 | [Risk Statements ]
R52/53:Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment . | [Safety Statements ]
S61:Avoid release to the environment. Refer to special instructions safety data sheet . | [WGK Germany ]
1 | [REACH Registrations]
Inactive | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Aquatic Acute 1
Aquatic Chronic 1 |
| Hazard Information | Back Directory | [Uses]
Herbicide. | [Definition]
ChEBI: Amidosulfuron is an aromatic ether. | [Production Methods]
The production of amidosulfuron involves a multi-step chemical synthesis. The key step includes reacting (N-methylsulfonyl-N-methylamino)sulfonamide with phenyl 4,6-dimethoxy-2-pyrimidylcarbamate in acetonitrile at room temperature for 18 hours. After partial solvent removal, water is added at 0 DegC, and the mixture is acidified to pH 2–3 using hydrochloric acid, prompting precipitation of the product. The solid is then filtered and washed, yielding amidosulfuron with high purity. | [Mechanism of action]
Selective, systemic absorbed through leaves and roots. Inhibits plant amino acid synthesis - acetohydroxyacid synthase AHAS | [Metabolic pathway]
The hydrolysis of 14C-amidosulfuron in buffer aqueous
solutions under various conditions results in 2-amino-
4,6-dimethoxypyrimidine as the major hydrolyzed
product. In soils, O-demethylated amidosulfuron is the
major degradation product. In mammals and plants,
primary hydroxylation at the pyrimidine ring is a
characteristic degradation reaction yielding
5-hydroxyamidosulfuron. | [Pesticide Type]
Herbicide |
|
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J & K SCIENTIFIC LTD.
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https://www.jkchemical.com |
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Struchem Co., Ltd.
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