| Identification | More | [Name]
Thiodiglycolic acid | [CAS]
123-93-3 | [Synonyms]
2,2'-DITHIODIACETIC ACID
2,2'-THIO-BIS(ACETIC ACID)
2,2'-THIODIACETIC ACID
2,2'-THIODIGLYCOLIC ACID
ACETIC ACID, 2,2'-THIOBIS-
BIS(CARBOXYMETHYL)-SULFIDE
CARBOXYMETHYL DISULFIDE
DICARBOXYDIMETHYL SULFIDE
DIMETHYL SULFIDE-ALPHA,ALPHA'-DICARBOXYLIC ACID
DITHIODIACETIC ACID
DITHIODIGLYCOLIC ACID
DITHIOGLYCOLIC ACID
MERCAPTODIACETIC ACID
RARECHEM AL BO 1549
SYM-DICARBOXY DIMETHYL DISULFIDE
THIODIACETIC ACID
THIODIGLYCOLIC ACID
THIODIGLYCOLLIC ACID
(carboxymethylthio)aceticacid
2,2’-thiobis-aceticaci | [EINECS(EC#)]
204-663-9 | [Molecular Formula]
C4H6O6S | [MDL Number]
MFCD00004359 | [Molecular Weight]
182.15 | [MOL File]
123-93-3.mol |
| Chemical Properties | Back Directory | [Appearance]
GREYISH CRYSTALLINE POWDER | [Melting point ]
128-131 °C(lit.) | [Boiling point ]
241.69°C (rough estimate) | [density ]
1.352 (estimate) | [refractive index ]
1.5500 (estimate) | [storage temp. ]
−20°C
| [solubility ]
400g/l | [form ]
Crystalline Powder | [pka]
pK1:3.32;pK2:4.29 (25°C) | [color ]
White to grayish | [PH]
2.2 (10g/l, H2O, 20℃) | [Water Solubility ]
soluble | [Sensitive ]
Stench | [Merck ]
14,9331 | [BRN ]
1764392 | [Henry's Law Constant]
2.2×108 mol/(m3Pa) at 25℃, HSDB (2015) | [Cosmetics Ingredients Functions]
REDUCING
ANTIOXIDANT | [InChI]
1S/C4H6O4S/c5-3(6)1-9-2-4(7)8/h1-2H2,(H,5,6)(H,7,8) | [InChIKey]
UVZICZIVKIMRNE-UHFFFAOYSA-N | [SMILES]
OC(=O)CSCC(O)=O | [LogP]
-0.780 (est) | [CAS DataBase Reference]
123-93-3(CAS DataBase Reference) | [EPA Substance Registry System]
123-93-3(EPA Substance) |
| Questions And Answer | Back Directory | [Synthesis]
Preparation of 2,2'-Thiodiacetic acid: 540 g (3.6 mol) of DL-methionine, 408 g (4.32 mol) of chloroacetic acid, and 3 L of water were added to a 5 L four-necked flask. The mixture was stirred until homogeneous and then slowly heated to 80 °C for 8 h. After the reaction was completed, the solvent water was recovered by cooling and reducing the pressure, yielding a total of 936 g of a mixture of DL-homoserine lactone hydrochloride, methionylacetic acid, and 2,2'-Thiodiacetic acid. |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H315-H319-H335 | [Precautionary statements ]
P302+P352-P305+P351+P338 | [Hazard Codes ]
C | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R34:Causes burns. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
UN 3261 8/PG 2
| [WGK Germany ]
3
| [RTECS ]
AJ6475000
| [F ]
13 | [Autoignition Temperature]
350 °C | [Hazard Note ]
Corrosive/Stench | [TSCA ]
Yes | [REACH Registrations]
Active | [HazardClass ]
8 | [PackingGroup ]
III | [HS Code ]
29309070 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 | [Safety Profile]
Poison by
intraperitoneal route. When heated to
decomposition or on contact with acid or
acid fumes it emits toxic fumes of SOx. See
also MERCAPTOACETIC ACID. | [Hazardous Substances Data]
123-93-3(Hazardous Substances Data) | [Toxicity]
LD50 orally in Rabbit: > 2000 mg/kg |
| Hazard Information | Back Directory | [Chemical Properties]
GREYISH CRYSTALLINE POWDER | [Uses]
Detection of copper, lead, mercury, silver: Dubsky et al., C.A. 34, 6185 (1940). | [Uses]
It finds it applications in the production of [1,4]oxathiane-2,6-dione by heating. It is employed as an anti-oxidant and reducing agent in cosmetics industry. | [Definition]
ChEBI: Thiodiacetic acid is a dicarboxylic acid. | [Purification Methods]
Crystallise the acid from water. [Beilstein 3 IV 612.] |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
|
| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
|