| Identification | Back Directory | [Name]
Bis-PEG10-acid | [CAS]
1268488-70-5 | [Synonyms]
1268488-70-5
Bis-PEG9-COOH
HOOC-PEG8-COOH
Bis-PEG10-acid
Bis-PEG25-acid
COOH-PEG8-COOH
HOOCCH2CH2O-PEG8-CH2CH2COOH
HOOCCH2CH2-PEG24-CH2CH2COOH
Bis-PEGn-CH2CH2COOH (n=9,25)
α,ω-dipropionic acid octaethylene glycol
4,7,10,13,16,19,22,25,28-Nonaoxahentriacontanedioic acid | [Molecular Formula]
C22H42O13 | [MDL Number]
MFCD28334514 | [MOL File]
1268488-70-5.mol | [Molecular Weight]
514.56 |
| Chemical Properties | Back Directory | [Boiling point ]
630.0±55.0 °C(Predicted) | [density ]
1.174±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,2-8°C | [form ]
Solid | [pka]
3.97±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Description]
Bis-PEG9-acid is a PEG linker containing two terminal carboxylic acid groups. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acids can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. | [Uses]
Bis-??PEG9-??acid is used in the preparation of plasma-stable dimeric inhibitors of PSD-95-NMDA receptor interaction. | [Biological Activity]
Bis-PEG10-acid is a PROTAC linker belonging to the PEG class. It can be used to synthesize a series of PROTAC molecules. It is a cleavable ADC linker for the synthesis of antibody-drug conjugates (ADCs). | [target]
| PEGs | Cleavable | [IC 50]
PEGs; Cleavable Linker |
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| Company Name: |
T&W GROUP
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| Telephone: |
021-61551611 13296011611 |
| Website: |
www.trustwe.com/ |
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Tags:1268488-70-5
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