| Identification | Back Directory | [Name]
alpha, oMega-Dipropionic acid hexaethylene glycol | [CAS]
94376-75-7 | [Synonyms]
94376-75-7
Bis-PEG7-COOH
Bis-PEG7-acid
Bis-PEG8-acid
HOOC-PEG6-COOH
COOH-PEG6-COOH
COOH-PEG7-COOH
Bis(3-PEG6)propionic acid
HOOCCH2CH2O-PEG6-CH2CH2COOH
α,ω-Dipropionic acid hexaethylene glycol
4,7,10,13,16,19,22-Heptaoxapentacosanedioic acid
alpha, oMega-Dipropionic acid hexaethylene glycol
3-(2-{2-[2-(2-{2-[2-(2-Carboxyethoxy)ethoxy]ethoxy}ethoxy)ethoxy]ethoxy}-ethoxy)propionic acid | [Molecular Formula]
C18H34O11 | [MDL Number]
MFCD11041125 | [MOL File]
94376-75-7.mol | [Molecular Weight]
426.46 |
| Hazard Information | Back Directory | [Description]
Bis-PEG7-acid is a PEG linker containing two terminal carboxylic acid groups. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acids can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. | [Uses]
Bis-PEG7-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG6-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. | [Biological Activity]
Bis-PEG7-acid is a PROTAC linker belonging to the PEG class. It can be used to synthesize a series of PROTAC molecules. It is a cleavable ADC linker for the synthesis of antibody-drug conjugates (ADCs). | [target]
| PEGs | Cleavable | [IC 50]
PEGs; Cleavable Linker | [References]
[1] Marc Stefan ROBILLARD, et al. Tetrazines for high click conjugation yield in vivo and high click release yield. WO2019212356A1 |
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T&W GROUP
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| Company Name: |
Nextpeptide Inc
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+86-0571-81612335 +8613336028439 |
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http://www.nextpeptide.com/ |
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Tags:94376-75-7
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