| Identification | Back Directory | [Name]
Bis-PEG6-acid | [CAS]
119189-70-7 | [Synonyms]
Bis-PEG6-COOH
HOOCCH2CH2O-PEG5-CH2CH2COOH
4,7,10,13,16,19-Hexaoxadocosanedioic acid
α,ω-dipropionic acid pentaethylene glycol
α,ω-dipropionic acid pentaethylene glycol
3,6,9,12,15,18-hexaoxaeicosanedicarboxylicacid | [Molecular Formula]
C16H30O10 | [MDL Number]
MFCD20926399 | [MOL File]
119189-70-7.mol | [Molecular Weight]
382.4 |
| Chemical Properties | Back Directory | [Boiling point ]
543.4±50.0 °C(Predicted) | [density ]
1.194±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
3.97±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Description]
Bis-PEG6-acid is a PEG linker containing two terminal carboxylic acid groups. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acids can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. | [Uses]
Bis-PEG6-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs | [IC 50]
PEGs |
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