| Identification | More | [Name]
Ethylenediaminetetraacetic acid tetrasodium salt | [CAS]
13235-36-4 | [Synonyms]
EDTA-4NA TETRAHYDRATE
EDTA, TETRA SODIUM SALT, TETRAHYDRATE
ETHYLENEDIAMINETETRAACETIC ACID TETRASODIUM SALT TETRAHYDRATE
ETHYLENEDIAMINE TETRAACETIC ACID TETRASODIUM TETRAHYDRATE
[ETHYLENEDINITRILO]TETRAACETIC ACID TETRASODIUM SALT TETRAHYDRATE
TETRASODIUM ETHYLENEDIAMINETETRAACETATE TETRAHYDRATE
TETRASODIUM SALT OF EDTA TETRA HYDRATE
ETHYLENEDIAMINETETRAACETIC ACID TETRASODIUM SALT HYDRATE PRACTICAL GRADE
ETHYLENEDIAMINETETRAACETIC ACID TETRASODIUM SALT HYDRATE SIGMAULTRA
ETHYLENEDIAMINETETRAACETIC ACID TETRASODIUM SALT HYDRATE PURUM
4Na(Edta4Na) 64-02-8
EDTA.Na.4H2O
Glycine, N,N-1,2-ethanediylbisN-(carboxymethyl)-, tetrasodium salt, tetrahydrate
Ethylenediaminetetraacetic acid tetrasodium salt
Tetrasodium Methylenediamine Tetraacetate | [EINECS(EC#)]
200-573-9 | [Molecular Formula]
C10H12N2Na4O8 | [MDL Number]
MFCD00150027 | [Molecular Weight]
380.17 | [MOL File]
13235-36-4.mol |
| Chemical Properties | Back Directory | [storage temp. ]
Inert atmosphere,Room Temperature | [solubility ]
H2O: 0.1 M at 20 °C, clear, colorless
| [form ]
Solid | [color ]
White crystalline | [Odor]
Odorless | [Water Solubility ]
almost transparency | [InChI]
InChI=1S/C10H16N2O8.Na.H2O.H/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;1H2; | [InChIKey]
LHCZUGDUAQREMU-UHFFFAOYSA-N | [SMILES]
N(CC(=O)O)(CC(=O)O)CCN(CC(=O)O)CC(=O)O.[NaH].O | [CAS DataBase Reference]
13235-36-4(CAS DataBase Reference) | [EPA Substance Registry System]
13235-36-4(EPA Substance) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H315-H319 | [Precautionary statements ]
P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
3
| [HS Code ]
2922.49.8000 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| Questions And Answer | Back Directory | [Description]
Ethylenediaminetetraacetic acid tetrasodium salt (also named as sodium edetate) can be formed by reacting a basic solution of ethylenediamine with formaldehyde and sodium or hydrogen cyanide, followed by hydrolysis to form the salt. It can also be produced by using excess sodium hydroxide in the reaction.1 In medicine, sodium edetate is used a s chelating agent to remove heavy metal, such as lead or mercury, from the blood. It is used to lower blood levels of calcium, to control heart rhythm disturbances cased by a heart medication.2 In food industry, it is used as an additive in flume water for washing fruits and vegetables. In industry, it is used in the formulations of anti-adhesive agents, corrosion inhibitors, anti-scaling agents, lubricant additives, surface active agents, etc.3,4 It is also used in photo-chemicals, textile treatment products and dyes, biocides (e.g. disinfectants, pest control products) and polishes and waxes.5
| [References]
- https://pubchem.ncbi.nlm.nih.gov/compound/16211056#section=Top
- https://www.drugs.com/mtm/edetate-disodium-edta.html
- http://www.efsa.europa.eu
- http://www.speiko.de
https://echa.europa.eu/substance-information/-/substanceinfo/100.000.522
[1] Jae Hyeon Jo. (2019). New Insight into Ethylenediaminetetraacetic Acid Tetrasodium Salt as a Sacrificing Sodium Ion Source for Sodium-Deficient Cathode Materials for Full Cells. ACS Applied Materials & Interfaces, 11 6, 5957–5965. https://doi.org/10.1021/acsami.8b1848
[2] Kate McKey. (2025). Piloting 4% Tetrasodium Ethylenediaminetetraacetic Acid (T-EDTA) Catheter Lock Solution in Renal Hemodialysis: A Quality Improvement Evaluation. Journal of Infusion Nursing, 48 6, 412–421. https://doi.org/10.1097/NAN.0000000000000620
[3] Jocelyn Hill, Rachel G. (2021). Efficacy of 4% tetrasodium ethylenediaminetetraacetic acid (T-EDTA) catheter lock solution in home parenteral nutrition patients: A quality improvement evaluation. Journal of Vascular Access, 22 4, 533–539. https://doi.org/10.1177/1129729820946916
|
| Hazard Information | Back Directory | [Uses]
Ethylenediaminetetraacetic Acid Tetrasodium Salt is a chelator used to eliminate inhibition of enzyme catalyzed reactions. It can be used as reactant/reagent for green preparation of O-allylhydroxylamines via organocatalytic oxidation of tertiary allylic amines followed by a [2,3]-Meisenheimer rearrangement. | [Biological Activity]
Primary Target
H+-ATPase | [Properties and Applications]
|
INDEX/GRADE
|
SPECIFICATION
|
|
Appearance
|
White crystal powder
|
|
Purity
|
99% min
|
|
Chloride (Cl
-
)
|
0.01% max
|
|
Sulfate(SO4
2-
)
|
0.05% max
|
|
Pb
|
0.001% max
|
|
Fe
|
0.001% max
|
|
Chelation value
|
220mg CaCO3/g min
|
|
pH value
|
10.5-11.5
|
|
NTA
|
1% max
|
|
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
Maya High Purity Chemicals
|
| Telephone: |
+86 (573) 82222445 (0)18006601000 452520369 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList15221/0_EN.htm |
| Company Name: |
T&W GROUP
|
| Telephone: |
021-61551611 13296011611 |
| Website: |
www.trustwe.com/ |
|