ChemicalBook--->CAS DataBase List--->13466-38-1

13466-38-1

13466-38-1 Structure

13466-38-1 Structure
IdentificationMore
[Name]

2-Hydroxy-5-bromopyridine
[CAS]

13466-38-1
[Synonyms]

2-HYDROXY-5-BROMOPYRIDINE
5-BROMO-2(1H)-PYRIDINONE
5-BROMO-2(1H)-PYRIDONE
5-BROMO-2-HYDROXYPYRIDINE
5-BROMO-2-PYRIDINOL
5-BROMO-2-PYRIDONE
5-BROMOPYRIDIN-2-OL
3-Bromo-6-hydroxypyridine
5-Bromo-2-pyridinol~5-Bromo-2-pyridone
5-BROMO-2-HYDROXYPYRIDINE, 97%%
5-Bromo-2-hydroxypyrdine
[EINECS(EC#)]

629-311-5
[Molecular Formula]

C5H4BrNO
[MDL Number]

MFCD00234042
[Molecular Weight]

174
[MOL File]

13466-38-1.mol
Questions And AnswerBack Directory
[Synthesis]

Starting with pyridine, 5-bromo-2-chloropyridine was synthesized via a halogenation reaction. Then, after hydrolysis with potassium alkoxide in a high-boiling alcohol solvent, the target compound 2-hydroxy-5-bromopyridine was obtained. The synthetic reaction formula is shown in the figure below:

Synthesis of 13466-38-1

Chemical PropertiesBack Directory
[Appearance]

off-white to yellow-brown crystalline powder
[Melting point ]

180-183 °C(lit.)
[Boiling point ]

305.9±42.0 °C(Predicted)
[density ]

1.776±0.06 g/cm3(Predicted)
[storage temp. ]

Keep in dark place,Inert atmosphere,Room temperature
[form ]

Crystalline Powder
[pka]

9.96±0.10(Predicted)
[color ]

Off-white to yellow-brown
[BRN ]

108751
[InChI]

InChI=1S/C5H4BrNO/c6-4-1-2-5(8)7-3-4/h1-3H,(H,7,8)
[InChIKey]

NDMZZQRNZFWMEZ-UHFFFAOYSA-N
[SMILES]

C1(=O)NC=C(Br)C=C1
[CAS DataBase Reference]

13466-38-1(CAS DataBase Reference)
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P264-P270-P301+P312-P302+P352-P305+P351+P338
[Hazard Codes ]

Xi,Xn
[Risk Statements ]

R36/37/38:Irritating to eyes, respiratory system and skin .
R36:Irritating to the eyes.
R22:Harmful if swallowed.
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S37/39:Wear suitable gloves and eye/face protection .
S36:Wear suitable protective clothing .
[WGK Germany ]

3
[Hazard Note ]

Irritant
[HazardClass ]

IRRITANT
[HS Code ]

29333990
[Storage Class]

11 - Combustible Solids
[Hazard Classifications]

Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Sodium nitrite-->Acetonitrile-->N-Bromosuccinimide-->Copper(II) sulfate pentahydrate-->2-Amino-5-bromopyridine-->2-Hydroxypyridine-->3-Bromo-2-hydroxypyridine
[Preparation Products]

5-Bromo-2-chloro-3-nitropyridine-->5-Bromo-2-chloropyridine-->3-Bromo-6-mercaptopyridine-->2(1H)-Pyridinone, 1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)--->2-Methoxy-3,5-dibromo-pyridine-->(E)-Tert-Butyl 3-(6-(Difluoromethoxy)Pyridin-3-Yl)Acrylate-->5-Bromo-1-(cyclopropylmethyl)pyridin-2(1H)-one
Hazard InformationBack Directory
[Chemical Properties]

off-white to yellow-brown crystalline powder
[Uses]

5-Bromopyridin-2-ol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
[General Description]

5-Bromo-2(1H)-pyridone undergoes difluormethylation in the presence of sodium chlorodifluoroacetate (ClCF2COONa) and methyl cyanide.
Spectrum DetailBack Directory
[Spectrum Detail]

2-Hydroxy-5-bromopyridine(13466-38-1)MS
2-Hydroxy-5-bromopyridine(13466-38-1)1HNMR
2-Hydroxy-5-bromopyridine(13466-38-1)IR1
2-Hydroxy-5-bromopyridine(13466-38-1)IR2
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

2-Hydroxy-5-bromopyridine, 99%(13466-38-1)
[Alfa Aesar]

5-Bromo-2-hydroxypyridine, 97%(13466-38-1)
[Sigma Aldrich]

13466-38-1(sigmaaldrich)
[TCI AMERICA]

5-Bromo-2-hydroxypyridine,>98.0%(GC)(T)(13466-38-1)
13466-38-1 suppliers list
Company Name: Changzhou Helios Biomedical Science and Technology Co.,LTD.  Gold
Telephone: 18961213068
Website: www.chemicalbook.com/ShowSupplierProductsList894733/0_EN.htm
Company Name: Taizhou Wealsun Biotech Co., Ltd  Gold
Telephone: 18351140886; 18351140886
Website:
Company Name: Nanjing Habo Medical Technology Co., Ltd.  Gold
Telephone: 13376080562 13376090521
Website: http://www.habotech.com
Company Name: Shanghai Taijilin Industrial Co., Ltd.  Gold
Telephone: 02150630626 17717886015
Website: http://www.tajilin.com/
Company Name: J & K SCIENTIFIC LTD.  
Telephone: 18210857532 18210857532
Website: https://www.jkchemical.com
Company Name: Meryer (Shanghai) Chemical Technology Co., Ltd.  
Telephone: 4006356688 18621169109
Website: www.x-labseek.com/
Company Name: future industrial shanghai co., ltd  
Telephone: 400-0066400 13621662912
Website: http://www.jonln.com
Company Name: Alfa Aesar  
Telephone: 400-6106006
Website: http://chemicals.thermofisher.cn
Company Name: TCI (Shanghai) Development Co., Ltd.  
Telephone: 021-67121386
Website: https://www.tcichemicals.com/CN/zh/
Company Name: ChangShu Haitian Fine Chemicals Co.,Ltd  
Telephone: 13913622609
Website: http://www.haitianchem.cn/
Company Name: BeiJing Hwrk Chemicals Limted  
Telephone: 0757-86329057 18934348241
Website: www.hwrkchemical.com/
Company Name: Energy Chemical  
Telephone: 400-0056266
Website: www.energy-chemical.com
Company Name: Shijiazhuang Sdyano Fine Chemical Co., Ltd.  
Telephone: 0311-89250318 13582355795
Website: www.sdynchem.com
Company Name: Wuhan Chemwish Technology Co., Ltd  
Telephone: 86-027-67849912
Website: www.chemwish.com
Company Name: Capot Chemical Co., Ltd  
Telephone: +86 (0) 571 85 58 67 18
Website: www.capotchem.com
Company Name: Beijing Ouhe Technology Co., Ltd  
Telephone: 13552068683 13522913783
Website: www.ouhetech.cn/
Company Name: JinYan Chemicals(ShangHai) Co.,Ltd.  
Telephone: 13817811078
Website: www.jingyan-chemical.com
Company Name: Accela ChemBio Co.,Ltd.  
Telephone: 021-50795510 4000665055
Website: http://www.shao-yuan.com/
Tags:13466-38-1 Related Product Information
140-72-7 51173-05-8 586-98-1 610-02-6 70258-18-3 137234-87-8 589-93-5 142-08-5 1914-99-4 126717-59-7 15862-34-7 13472-85-0 13472-81-6 55849-30-4 74115-13-2 55717-45-8 13466-43-8 6602-32-0